Property, Plant, and Equipment

12 Months Ended

Dec. 31, 2019

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

Property, Plant, and Equipment

Property, plant, and equipment consists of the following:

	As of December 31,
	2019			2018
Land	$	230.8		$	199.0
Building and improvements	1,683.4			1,507.2
Leasehold improvements	97.6			97.0
Construction in progress	644.8			469.6
Laboratory equipment	850.7			773.7
Computer equipment and software	183.7			145.8
Furniture, office equipment, and other	121.8			112.2
	3,812.8			3,304.5
Less, accumulated depreciation and amortization	(922.4		)	(728.7		)
	$	2,890.4		$	2,575.8

Property, plant, and equipment in the table above includes leased property under the Company's finance lease at its Tarrytown, New York facility. See Note 11.

Depreciation and amortization expense (including as it relates to the Company's finance lease) on property, plant, and equipment amounted to $205.2 million, $144.1 million, and $142.2 million for the years ended December 31, 2019, 2018, and 2017, respectively.

As of December 31, 2019 and 2018, $2,117.6 million and $1,813.8 million, respectively, of the Company's net property, plant, and equipment was located in the United States and $772.8 million and $762.0 million, respectively, was located in Europe (primarily in Ireland).