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Collaboration Agreements - Schedule of Significant Changes in Deferred Revenue Balances, Antibody Collaboration (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2019
Mar. 31, 2018
Disaggregation of Revenue [Line Items]    
Increase (decrease) in deferred revenue $ 426.5 $ (54.5)
Sanofi Collaboration Agreement, Antibody    
Disaggregation of Revenue [Line Items]    
Increase (decrease) in deferred revenue 86.0  
Revenue recognized that was included in deferred revenue at the beginning of the period $ (20.1)