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Collaboration and License Agreements - Schedule of Accounts Receivable and Deferred Revenue Information, IO Collaboration (Details) - USD ($)
$ in Millions
Dec. 31, 2018
Dec. 31, 2017
Disaggregation of Revenue [Line Items]    
Accounts receivable $ 226.4 $ 193.7
Sanofi Collaboration Agreement, Immuno-oncology    
Disaggregation of Revenue [Line Items]    
Accounts receivable 77.9 59.3
Deferred revenue $ 289.9 $ 440.0