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Interim Financial Statements - Schedule of Balance Sheet Data (Details) - USD ($)
$ in Thousands
Sep. 30, 2018
Dec. 31, 2017
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Inventories $ 1,039,679 $ 726,138
Deferred tax assets 562,818 506,291
Total assets 10,805,613 8,764,286
Accrued expenses and other current liabilities 781,924 637,162
Total current liabilities 1,417,230 1,135,483
Total liabilities 2,937,313 2,620,208
Retained earnings 4,433,904 2,946,733
Total stockholders' equity 7,868,300 6,144,078
Total liabilities and stockholders' equity 10,805,613 8,764,286
Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Inventories 1,057,197  
Deferred tax assets 547,791  
Total assets 10,808,104  
Accrued expenses and other current liabilities 780,749  
Total current liabilities 1,277,038  
Total liabilities 2,801,995  
Retained earnings 4,571,713  
Total stockholders' equity 8,006,109  
Total liabilities and stockholders' equity 10,808,104  
Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Inventories 17,518  
Deferred tax assets (15,027)  
Total assets 2,491  
Accrued expenses and other current liabilities (1,175)  
Total current liabilities (140,192)  
Total liabilities (135,318)  
Retained earnings 137,809  
Total stockholders' equity 137,809  
Total liabilities and stockholders' equity 2,491  
Sanofi    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 246,812 177,746
Deferred revenue, noncurrent 421,196 379,936
Sanofi | Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 186,406  
Deferred revenue, noncurrent 393,118  
Sanofi | Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current (60,406)  
Deferred revenue, noncurrent (28,078)  
Other    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 216,133 142,392
Deferred revenue, noncurrent 197,651 $ 249,263
Other | Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 137,522  
Deferred revenue, noncurrent 230,603  
Other | Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current (78,611)  
Deferred revenue, noncurrent $ 32,952