Collaboration Agreements Schedule of Accounts Receivable and Deferred Revenue Information - IO Collaboration (Details) - USD ($) $ in Thousands	Jun. 30, 2018	Dec. 31, 2017
Disaggregation of Revenue [Line Items]
Accounts receivable, net	$ 243,238	$ 193,684
Sanofi Collaboration Agreement, Immuno-oncology
Disaggregation of Revenue [Line Items]
Accounts receivable, net	76,522	59,274
Deferred revenue	$ 476,312	$ 440,000

Amount of receivables arising from transactions with related parties due within one year or the normal operating cycle, if longer.

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