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Interim Financial Statements Schedule of Statements of Operations Data (Details) - USD ($)
$ in Thousands
3 Months Ended 6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Jun. 30, 2018
Jun. 30, 2017
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ 1,608,022 $ 1,470,116 $ 3,119,507 $ 2,789,107
Income from operations 622,188 550,312 1,189,419 980,854
Income before income taxes 656,074 525,850 1,241,472 958,139
Income tax expense (104,662) (138,106) (212,080) (321,464)
Net income 551,412 387,744 1,029,392 636,675
Balance Without Adoption of ASC 606        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 1,569,219   3,054,987  
Income from operations 583,385   1,124,899  
Income before income taxes 617,271   1,176,952  
Income tax expense (102,748)   (208,378)  
Net income 514,523   968,574  
Accounting Standards Update 2014-09 | Adjustments        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues (38,803)   (64,520)  
Income from operations (38,803)   (64,520)  
Income before income taxes (38,803)   (64,520)  
Income tax expense 1,914   3,702  
Net income (36,889)   (60,818)  
Sanofi | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 237,753 222,128 427,243 432,495
Sanofi | Balance Without Adoption of ASC 606 | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 228,829   409,912  
Sanofi | Accounting Standards Update 2014-09 | Adjustments | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues (8,924)   (17,331)  
Other | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 111,024 $ 113,500 197,182 $ 169,940
Other | Balance Without Adoption of ASC 606 | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues 81,145   149,993  
Other | Accounting Standards Update 2014-09 | Adjustments | Product and service, other        
New Accounting Pronouncements or Change in Accounting Principle [Line Items]        
Revenues $ (29,879)   $ (47,189)