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Interim Financial Statements Schedule of Balance Sheet Data (Details) - USD ($)
$ in Thousands
Jun. 30, 2018
Dec. 31, 2017
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred tax assets $ 545,077 $ 506,291
Total assets 9,951,980 8,764,286
Accrued expenses and other current liabilities 670,709 637,162
Total current liabilities 1,331,190 1,135,483
Total liabilities 2,765,554 2,620,208
Retained earnings 3,839,179 2,946,733
Total stockholders' equity 7,186,426 6,144,078
Total liabilities and stockholders' equity 9,951,980 8,764,286
Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred tax assets 528,784  
Total assets 9,935,687  
Accrued expenses and other current liabilities 669,196  
Total current liabilities 1,196,875  
Total liabilities 2,666,644  
Retained earnings 3,921,796  
Total stockholders' equity 7,269,043  
Total liabilities and stockholders' equity 9,935,687  
Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred tax assets (16,293)  
Total assets (16,293)  
Accrued expenses and other current liabilities (1,513)  
Total current liabilities (134,315)  
Total liabilities (98,910)  
Retained earnings 82,617  
Total stockholders' equity 82,617  
Total liabilities and stockholders' equity (16,293)  
Sanofi    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 308,179 177,746
Deferred revenue, noncurrent 339,040 379,936
Sanofi | Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 225,196  
Deferred revenue, noncurrent 345,711  
Sanofi | Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current (82,983)  
Deferred revenue, noncurrent 6,671  
Other    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 180,396 142,392
Deferred revenue, noncurrent 199,401 $ 249,263
Other | Balance Without Adoption of ASC 606    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current 130,577  
Deferred revenue, noncurrent 228,135  
Other | Adjustments | Accounting Standards Update 2014-09    
New Accounting Pronouncements or Change in Accounting Principle [Line Items]    
Deferred revenue, current (49,819)  
Deferred revenue, noncurrent $ 28,734