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Collaboration Agreements (Intellia Therapeutics) (Details) - USD ($)
1 Months Ended 6 Months Ended 12 Months Ended
Apr. 30, 2016
Jun. 30, 2016
Dec. 31, 2017
Dec. 31, 2016
Dec. 31, 2015
Collaboration Agreements [Line Items]          
Payments to Acquire Marketable Securities     $ 1,277,140,000 $ 809,419,000 $ 557,105,000
Intella Therapeutics [Member]          
Collaboration Agreements [Line Items]          
Upfront Payment Made $ 75,000,000        
Payments to Acquire Marketable Securities   $ 50,000,000.0