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Collaboration Agreements (Bayer) (Details) - USD ($)
$ in Thousands
3 Months Ended 9 Months Ended
Sep. 30, 2017
Sep. 30, 2016
Sep. 30, 2017
Sep. 30, 2016
Collaboration Agreement [Line Items]        
Other Collaboration Revenue $ 236,625 $ 191,298 $ 640,919 $ 562,786
EYLEA        
Collaboration Agreement [Line Items]        
Net profit (loss) from commercialization of products under collaboration agreement 205,367 170,854 571,126 484,181
Reimbursement of Regeneron research and development expenses 6,053 2,219 10,833 7,186
Contracts Revenue 15,714 6,077 36,910 45,924
Other Collaboration Revenue 227,134 179,150 618,869 537,291
Ang2 antibody and PDGFR-beta antibody        
Collaboration Agreement [Line Items]        
Reimbursement of Regeneron research and development expenses 7,325 7,433 15,614 14,165
Contracts Revenue 2,166 4,715 6,436 11,330
Other Collaboration Revenue $ 9,491 $ 12,148 $ 22,050 $ 25,495