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Inventory (Notes)
3 Months Ended
Mar. 31, 2017
Inventory Disclosure [Abstract]  
Inventory
Inventories
Inventories consist of the following:
 
March 31,
 
December 31,
 
2017
 
2016
Raw materials
$
127,637

 
$
92,287

Work-in-process
173,469

 
202,301

Finished goods
20,259

 
13,334

Deferred costs
145,211

 
91,434

 
$
466,576

 
$
399,356


Deferred costs represent the costs of product manufactured and shipped to the Company's collaborators for which recognition of revenue has been deferred. For the three months ended March 31, 2017 and 2016, cost of goods sold included inventory write-downs and reserves totaling $6.4 million and $4.3 million, respectively.