Commitments and Contingencies - Facility Leases (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Schedule of Facility Leases [Line Items]
2017	$ 32,117
2018	33,141
2019	33,942
2020	34,763
2021	35,603
Thereafter	278,928
Total	448,494
Facility lease obligations [Abstract]
Interest expense in connection with facility lease obligation	5,400	$ 9,700	$ 14,500
Commitments under facility leases [Abstract]
Facility lease obligation, including reimbursements	353,852	364,708
Facilities - Buildings A and B
Schedule of Facility Leases [Line Items]
2017	13,965
2018	14,242
2019	14,526
2020	14,818
2021	15,116
Thereafter	101,010
Total	$ 173,677
Facility lease obligations [Abstract]
Imputed interest rate applicable to facility lease obligation	12.00%
Commitments under facility leases [Abstract]
Facility lease obligation, including reimbursements	$ 99,323	108,857
Facilities - Building C
Schedule of Facility Leases [Line Items]
2017	4,740
2018	4,873
2019	5,009
2020	5,149
2021	5,292
Thereafter	48,801
Total	$ 73,864
Facility lease obligations [Abstract]
Imputed interest rate applicable to facility lease obligation	11.00%
Commitments under facility leases [Abstract]
Facility lease obligation, including reimbursements	$ 44,338	49,475
Facilities Building D and E
Schedule of Facility Leases [Line Items]
2017	12,922
2018	13,267
2019	13,621
2020	13,983
2021	14,354
Thereafter	121,927
Total	$ 190,074
Facility lease obligations [Abstract]
Imputed interest rate applicable to facility lease obligation	7.00%
Commitments under facility leases [Abstract]
Facility lease obligation, including reimbursements	$ 194,037	206,376
Facilities Building F [Member]
Schedule of Facility Leases [Line Items]
2017	490
2018	759
2019	786
2020	813
2021	841
Thereafter	7,190
Total	$ 10,879
Facility lease obligations [Abstract]
Imputed interest rate applicable to facility lease obligation	10.00%
Commitments under facility leases [Abstract]
Facility lease obligation, including reimbursements	$ 16,154	$ 0