Property, Plant, and Equipment (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015	Dec. 31, 2014
Property, Plant and Equipment [Line Items]
Land, Gross	$ 103,906	$ 77,826
Buildings and Improvements, Gross	1,278,283	760,517
Leasehold Improvements, Gross	101,101	95,226
Construction in Progress, Gross	318,929	579,834
Costs incurred by the landlord to construct new laboratory and office facilities	554,181	330,432
Furniture and Fixtures, Gross	152,525	81,381
Property, plant, and equipment, gross	2,508,925	1,925,216
Less: accumulated depreciation and amortization	(425,504)	(331,096)
Property, plant, and equipment, net	2,083,421	1,594,120
Depreciation and amortization expense	104,745	74,909	$ 52,686
Capital Lease Obligations, Current	127,274	0
Building and improvements
Property, Plant and Equipment [Line Items]
Buildings and Improvements, Gross	269,000	254,600
UNITED STATES
Property, Plant and Equipment [Line Items]
Property, plant, and equipment, net	1,441,200	1,118,400
Foreign
Property, Plant and Equipment [Line Items]
Property, plant, and equipment, net	642,200	475,700
Tarrytown, New York | Land [Member]
Property, Plant and Equipment [Line Items]
Property, Plant and Equipment, Additions		$ 73,000
Tarrytown, New York
Property, Plant and Equipment [Line Items]
Capital Lease Obligations, Current	$ 138,100