XML 66 R47.htm IDEA: XBRL DOCUMENT v3.6.0.2
Collaboration Agreements (EYLEA) (Details) - USD ($)
$ in Thousands
1 Months Ended 3 Months Ended 9 Months Ended 12 Months Ended
Aug. 31, 2007
Oct. 31, 2006
Mar. 31, 2014
Sep. 30, 2016
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Collaboration Agreements [Line Items]              
Period for Achieving Sales Target for Milestone Payment, Rolling Basis             12 months
Levels of twelve month sales at which sales milestone payments were received             $ 500,000
level of twelve months sales at which sales milestone payments maybe received - 100 million             100,000
Accounts receivable from Bayer HealthCare         $ 175,263 $ 162,152  
Collaboration Agreement with Bayer HealthCare LLC              
Collaboration Agreements [Line Items]              
Percentage of repayment of development balance out of profits         50.00%    
Contingent reimbursement obligation         $ 256,000    
Revenue Recognition, Milestone Method, Revenue Recognized         0 15,000 105,000
Levels of twelve months sales at which sales milestone payments were received - 200 million           200,000  
Research and Development Arrangement, Contract to Perform for Others, Compensation Earned         $ 9,010 8,887 23,383
Minimum advance notice required to terminate collaboration agreement         6 months    
Proceeds from Collaborators $ 20,000 $ 75,000          
Other Research and Development Expense         $ 1,400 $ 13,700 18,600
Deferred Revenue, Additions $ 20,000 $ 75,000          
maximum advance notice required to terminate collaboration agreement         12 months    
BRVO              
Collaboration Agreements [Line Items]              
Research and Development Arrangement, Contract to Perform for Others, Compensation Earned     $ 15,700        
starting at sales achievement - $200 million              
Collaboration Agreements [Line Items]              
Period for Achieving Sales Target for Milestone Payment, Rolling Basis           12 months  
starting at sales achievement - $500 million              
Collaboration Agreements [Line Items]              
Revenue Recognition, Milestone Method, Revenue Recognized             90,000
sales achievement - 200 million              
Collaboration Agreements [Line Items]              
Maximum amount of sales milestone payments if total sales achieve specific levels             $ 15,000
sales achievement - 100 million              
Collaboration Agreements [Line Items]              
Period for Achieving Sales Target for Milestone Payment, Rolling Basis             12 months
Maximum amount of sales milestone payments if total sales achieve specific levels           $ 15,000  
Minimum | Collaboration Agreement with Bayer HealthCare LLC              
Collaboration Agreements [Line Items]              
Revenue based on percentage of annual sales in Japan       33.50%      
Maximum | Collaboration Agreement with Bayer HealthCare LLC              
Collaboration Agreements [Line Items]              
Revenue based on percentage of annual sales in Japan       40.00%