Income Taxes (Tables)

12 Months Ended

Dec. 31, 2016

Schedule of Income before Income Tax, Domestic and Foreign [Table Text Block]

Components of income before income taxes consist of the following:



	Year Ended December 31,
	2016			2015			2014
United States	$	1,650,959		$	1,665,087		$	1,101,446
Foreign	(321,144		)	(439,990		)	(340,211		)
	$	1,329,815		$	1,225,097		$	761,235

Schedule of Components of Income Tax Expense (Benefit)

Components of income tax expense consist of the following:



		Year Ended December 31,
		2016			2015			2014
Current:
	Federal	$	786,964		$	686,561		$	437,038
	State	8,769			28,568			28,718
	Foreign	(1,362		)	4,004			2,879
	Total current tax expense	794,371			719,133			468,635
Deferred:
	Federal	(377,368		)	(119,849		)	(62,932		)
	State	13,431			(3,768		)	18,891
	Foreign	3,859			(6,475		)	(1,485		)
	Total deferred tax (benefit) expense	(360,078		)	(130,092		)	(45,526		)
		$	434,293		$	589,041		$	423,109

Schedule of Effective Income Tax Rate Reconciliation

A reconciliation of the U.S. statutory income tax rate to the Company's effective income tax rate is as follows:



	Year Ended December 31,
	2016		2015		2014
U.S. federal statutory tax rate	35.0	%	35.0	%	35.0	%
Stock-based compensation	(10.9	)	—		—
State and local income taxes	0.3		1.0		2.4
Change in state effective rate	1.0		(0.1	)	2.9
Foreign income tax rate differential	8.8		12.2		15.8
Income tax credits	(1.2	)	(1.6	)	(5.1	)
Non-deductible Branded Prescription Drug Fee	1.9		2.0		2.8
Domestic production activities deduction	(2.8	)	(3.2	)	—
Other permanent differences	0.6		2.8		1.8
Effective income tax rate	32.7	%	48.1	%	55.6	%

Schedule of Deferred Tax Assets and Liabilities

Significant components of the Company's deferred tax assets and liabilities are as follows:



	As of December 31,
	2016			2015
Deferred tax assets:
Net operating loss carryforward	$	137		$	140
Fixed and intangible assets	21,139			—
Deferred revenue	214,587			51,766
Deferred compensation	515,984			349,508
Capitalized research and development costs	2,492			7,725
Accrued expenses	37,188			47,520
Other	46,471			26,580
	837,998			483,239
Valuation allowance	(3,420		)	—
Total deferred tax assets	834,578			483,239

Deferred tax liabilities:
Unrealized gains/losses on marketable securities	—			(3,280		)
Fixed assets and intangible assets	—			(5,559		)
Other	(9,275		)	(12,455		)
Total deferred tax liabilities	(9,275		)	(21,294		)
Net deferred tax assets	$	825,303		$	461,945

Schedule Of Unrecognized Tax Benefits Roll Forward

The following table summarizes the gross amounts of unrecognized tax benefits. The amount of unrecognized tax benefits that, if settled, would impact the effective tax rate is $107.2 million, $102.1 million, and $51.2 million as of December 31, 2016, 2015, and 2014, respectively.



	2016			2015			2014
Balance as of January 1	$	116,572		$	57,615		$	26,627
Gross increases related to current year tax positions	45,575			59,909			27,538
Gross (decreases) increases related to prior year tax positions	(42,284		)	(952		)	6,464
Gross decrease due to settlements, recapture, filed returns, and lapse of statutes of limitation	(2,697		)	—			(3,014		)
Balance as of December 31	$	117,166		$	116,572		$	57,615