Property, Plant, and Equipment (Tables)

12 Months Ended

Dec. 31, 2016

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

Property, plant, and equipment consist of the following:

	As of December 31,
	2016			2015
Land	$	103,906		$	77,826
Building and improvements	1,278,283			760,517
Leasehold improvements	101,101			95,226
Construction-in-progress	318,929			579,834
Laboratory and other equipment	554,181			330,432
Furniture, computer and office equipment, and other	152,525			81,381
	2,508,925			1,925,216
Less, accumulated depreciation and amortization	(425,504		)	(331,096		)
	$	2,083,421		$	1,594,120