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Collaboration Agreements (Intella Therapeutics) (Details)
1 Months Ended 6 Months Ended 9 Months Ended
Apr. 30, 2016
USD ($)
target
Jun. 30, 2016
USD ($)
shares
Sep. 30, 2016
USD ($)
Sep. 30, 2015
USD ($)
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Payments to Acquire Marketable Securities     $ 606,153,000 $ 550,142,000
Intella Therapeutics [Member]        
Research and Development Arrangement, Contract to Perform for Others [Line Items]        
Upfront Payment Made $ 75,000,000      
Collaboration Agreement, Number of Targets Company May Have Rights To | target 10      
Collaboration Agreement, Extension Period 2 years      
Investment obligation   $ 50,000,000    
Shares of Common Stock Purchased | shares   2,777,777    
Payments to Acquire Marketable Securities   $ 50,000,000.0