A roll forward is a reconciliation of a concept from the beginning of a period to the end of a period.

No definition available.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

+ Details

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- Definition

Aggregate revenue during the period from the sale of goods in the normal course of business, after deducting returns, allowances and discounts.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 225
-SubTopic 10
-Section S99
-Paragraph 2
-Subparagraph (SX 210.5-03.1(a))
-URI http://asc.fasb.org/extlink&oid=26872669&loc=d3e20235-122688

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- Definition

Total of allowances and reserves, the valuation and qualifying accounts that are either netted against the cost of an asset (in order to value it at its carrying value) or that reflect a liability established to represent expected future costs.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 235
-SubTopic 10
-Section S99
-Paragraph 4
-URI http://asc.fasb.org/extlink&oid=26873400&loc=d3e24092-122690

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Regulation S-X (SX)
-Number 210
-Section 09
-Article 12

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- Definition

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- Definition

Total of the deductions in a given period to allowances and reserves, the valuation and qualifying accounts that are either netted against the cost of an asset (in order to value it at its carrying value) or that reflect a liability established to represent expected future costs, representing receivables written off as uncollectible and portions of the reserves utilized, respectively.

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Net Product Sales (Details) - USD ($) $ in Thousands	3 Months Ended		9 Months Ended
Net Product Sales (Details) - USD ($) $ in Thousands	Sep. 30, 2016	Sep. 30, 2015	Sep. 30, 2016	Sep. 30, 2015	Dec. 31, 2015	Dec. 31, 2014
Revenue Disclosure [Line Items]
Net product sales	$ 857,468	$ 737,562	$ 2,475,869	$ 1,939,954
Activity of Sales Related Deductions [Roll Forward]
Balance	37,753	45,074	37,753	45,074	$ 55,249	$ 24,781
Provision related to current period sales			200,077	135,363
Credits/payments			(217,573)	(115,070)
Rebates and Chargebacks
Activity of Sales Related Deductions [Roll Forward]
Balance	7,426	6,362	7,426	6,362	6,419	3,083
Provision related to current period sales			63,510	41,290
Credits/payments			(62,503)	(38,011)
Distribution Related Fees
Activity of Sales Related Deductions [Roll Forward]
Balance	26,585	38,208	26,585	38,208	48,313	21,166
Provision related to current period sales			113,755	88,049
Credits/payments			(135,483)	(71,007)
Other Sales Related Deductions
Activity of Sales Related Deductions [Roll Forward]
Balance	3,742	504	3,742	504	$ 517	$ 532
Provision related to current period sales			22,812	6,024
Credits/payments			(19,587)	(6,052)
EYLEA
Revenue Disclosure [Line Items]
Net product sales	853,600	734,400	2,465,400	1,930,000
ARCALYST
Revenue Disclosure [Line Items]
Net product sales	$ 3,900	$ 3,200	$ 10,500	$ 9,900