Property, Plant, and Equipment (Tables)

12 Months Ended

Dec. 31, 2015

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

Property, plant, and equipment consist of the following:

	As of December 31,
	2015			2014
Land	$	77,826		$	2,768
Building and improvements	760,517			398,981
Leasehold improvements	95,226			42,600
Construction-in-progress	579,834			472,231
Laboratory and other equipment	330,432			253,058
Furniture, computer and office equipment, and other	81,381			58,655
	1,925,216			1,228,293
Less, accumulated depreciation and amortization	(331,096		)	(253,984		)
	$	1,594,120		$	974,309