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Net Product Sales (Tables)
 12 Months Ended
Dec. 31, 2015
Revenues [Abstract]  
Sales Related Deductions Activity
The following table summarizes the provisions, and credits/payments, for these sales-related deductions for the years ended December 31, 2015, 2014, and 2013.
 
Rebates &
Chargebacks
 
Distribution-
Related
Fees
 
Other Sales-
Related
Deductions
 
Total
Balance as of December 31, 2012
$
2,983

 
$
15,298

 
$
545

 
$
18,826

Provision related to current period sales
25,936

 
62,984

 
955

 
89,875

Credits/payments
(24,519
)
 
(58,619
)
 
(962
)
 
(84,100
)
Balance as of December 31, 2013
4,400

 
19,663

 
538

 
24,601

Provision related to current period sales
33,117

 
77,160

 
1,578

 
111,855

Credits/payments
(34,434
)
 
(75,657
)
 
(1,584
)
 
(111,675
)
Balance as of December 31, 2014
3,083

 
21,166

 
532

 
24,781

Provision related to current period sales
61,124

 
122,466

 
9,600

 
193,190

Credits/payments
(57,788
)
 
(95,319
)
 
(9,615
)
 
(162,722
)
Balance as of December 31, 2015
$
6,419

 
$
48,313

 
$
517

 
$
55,249