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Inventory
12 Months Ended
Dec. 31, 2015
Inventory Disclosure [Abstract]  
Inventory
Inventories
Inventories consist of the following:
 
As of December 31,
 
2015
 
2014
Raw materials
$
59,151

 
$
10,923

Work-in-process
132,068

 
73,519

Finished goods
11,197

 
10,768

Deferred costs
36,162

 
33,651

 
$
238,578

 
$
128,861


Deferred costs represent the costs of product manufactured and shipped to the Company's collaborators for which recognition of revenue has been deferred (see Note 1). In 2015, 2014, and 2013, cost of goods sold included inventory write-downs and reserves totaling $10.6 million, $6.0 million, and $9.1 million, respectively.