XML 42 R24.htm IDEA: XBRL DOCUMENT v3.3.0.814
Collaboration Agreements (Tables)
9 Months Ended
Sep. 30, 2015
Collaboration Agreement [Abstract]  
Collaboration revenue with related party
Sanofi collaboration revenue, as detailed below, consisted primarily of reimbursement for research and development and commercialization expenses that the Company incurred, partly offset by sharing of losses in connection with commercialization of antibodies, under the companies' Discovery and Preclinical Development Agreement ("Antibody Discovery Agreement") and License and Collaboration Agreement (each as amended), collectively referred to as the "Antibody Collaboration". In addition, in July 2015, the Company and Sanofi entered into a collaboration to discover, develop, and commercialize antibody-based cancer treatments in the field of immuno-oncology (the "IO Collaboration").
 
 
Three Months Ended
September 30,
Sanofi Collaboration Revenue
 
2015
 
2014
Antibody:
 
 
 
 
Reimbursement of Regeneron research and development expenses
 
$
205,114

 
$
140,497

Reimbursement of Regeneron commercialization-related expenses
 
53,341

 
1,688

Regeneron's share of losses in connection with commercialization of antibodies
 
(74,865
)
 
(12,830
)
Other
 
2,561

 
2,561

Total Antibody
 
186,151

 
131,916

Immuno-oncology:
 
 
 
 
Reimbursement of Regeneron research and development expenses
 
18,584

 

Other
 
20,000

 

Total Immuno-oncology
 
38,584

 

ZALTRAP®:
 
 
 
 
Regeneron's share of losses in connection with commercialization of ZALTRAP
 

 
(1,008
)
Reimbursement of Regeneron research and development expenses
 

 
1,261

Other
 

 
756

Total ZALTRAP
 

 
1,009

 
 
$
224,735

 
$
132,925



 
 
Nine Months Ended
September 30,
Sanofi Collaboration Revenue
 
2015
 
2014
Antibody:
 
 
 
 
Reimbursement of Regeneron research and development expenses
 
$
585,450

 
$
405,212

Reimbursement of Regeneron commercialization-related expenses
 
89,145

 
7,062

Regeneron's share of losses in connection with commercialization of antibodies
 
(143,583
)
 
(17,125
)
Other
 
7,683

 
7,683

Total Antibody
 
538,695

 
402,832

Immuno-oncology:
 
 
 
 
Reimbursement of Regeneron research and development expenses
 
18,584

 

Other
 
20,000

 

Total Immuno-oncology
 
38,584

 

ZALTRAP:
 
 
 
 
Regeneron's share of losses in connection with commercialization of ZALTRAP
 

 
(4,912
)
Reimbursement of Regeneron research and development expenses
 
686

 
3,691

Other
 
15,236

 
4,417

Total ZALTRAP
 
15,922

 
3,196

 
 
$
593,201

 
$
406,028

Collaboration revenue
The collaboration revenue the Company earned from Bayer HealthCare is detailed below:
 
 
Three Months Ended
September 30,
Bayer HealthCare Collaboration Revenue
 
2015
 
2014
EYLEA:
 
 
 
 
Regeneron's net profit in connection with commercialization of EYLEA outside the United States
 
$
130,510

 
$
85,351

Sales milestones
 

 
30,000

Cost-sharing of Regeneron EYLEA development expenses
 
1,827

 
4,394

Other
 
21,155

 
12,745

Total EYLEA
 
153,492

 
132,490

PDGFR-beta antibody:
 
 
 
 
Cost-sharing of REGN2176-3 development expenses
 
1,508

 
518

Other
 
2,596

 
2,845

Total PDGFR-beta
 
4,104

 
3,363

 
 
$
157,596

 
$
135,853


 
 
Nine Months Ended
September 30,
Bayer HealthCare Collaboration Revenue
 
2015
 
2014
EYLEA:
 
 
 
 
Regeneron's net profit in connection with commercialization of EYLEA outside the United States
 
$
326,567

 
$
213,291

Sales milestones
 
15,000

 
75,000

Cost-sharing of Regeneron EYLEA development expenses
 
6,948

 
26,235

Other
 
50,685

 
34,490

Total EYLEA
 
399,200

 
349,016

PDGFR-beta antibody:
 
 
 
 
Cost-sharing of REGN2176-3 development expenses
 
8,688

 
1,657

Other
 
7,791

 
7,787

Total PDGFR-beta
 
16,479

 
9,444

 
 
$
415,679

 
$
358,460