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Collaboration Agreements (Tables)
12 Months Ended
Dec. 31, 2014
Collaboration Agreement [Abstract]  
Schedule of Related Party Transactions [Table Text Block]
The collaboration revenue the Company earned from Sanofi is detailed below:
 
 
Year Ended December 31,
Sanofi Collaboration Revenue
 
2014
 
2013
 
2012
ZALTRAP:
 
 
 
 
 
 
Regeneron's share of losses in connection with commercialization of ZALTRAP
 
$
(4,715
)
 
$
(30,810
)
 
$
(25,634
)
Substantive milestone
 

 

 
50,000

Reimbursement of Regeneron research and development expenses
 
4,806

 
5,639

 
10,702

Other
 
5,102

 
9,682

 
13,268

Total ZALTRAP
 
5,193

 
(15,489
)
 
48,336

Antibody:
 
 
 
 
 
 
Reimbursement of Regeneron research and development expenses
 
547,761

 
453,489

 
365,245

Reimbursement of Regeneron commercialization-related expenses
 
19,480

 
1,868

 

Regeneron's share of losses in connection with commercialization of antibodies
 
(41,378
)
 

 

Up-front payments to Sanofi for acquisition of rights related to two antibodies
 

 
(20,000
)
 

Other
 
10,243

 
10,243

 
10,233

Total Antibody
 
536,106

 
445,600

 
375,478

 
 
$
541,299

 
$
430,111

 
$
423,814

Collaboration revenue
The collaboration revenue the Company earned from Bayer HealthCare is detailed below:
 
 
Year Ended December 31,
Bayer HealthCare Collaboration Revenue
 
2014
 
2013
 
2012
EYLEA:
 
 
 
 
 
 
Regeneron's net profit in connection with commercialization of EYLEA outside the United States
 
$
301,302

 
$
101,494

 

Sales and substantive development milestones
 
105,000

 
70,000

 
$
25,000

Cost-sharing of Regeneron EYLEA development expenses
 
23,383

 
20,905

 
34,892

Other
 
52,390

 
27,890

 
10,207

Total EYLEA
 
482,075

 
220,289

 
70,099

PDGFR-beta antibody:
 
 
 
 
 
 
Cost-sharing of REGN2176-3 development expenses
 
2,848

 

 

Other
 
10,632

 

 

Total PDGFR-beta
 
13,480

 

 

 
 
$
495,555

 
$
220,289

 
$
70,099