Accounts Payable and Accrued Expenses (Details) (USD $) In Thousands, unless otherwise specified	Sep. 30, 2014	Dec. 31, 2013
Accounts Payable and Accrued Liabilities, Current [Abstract]
Accounts payable	$ 47,342	$ 61,936
Accrued payroll and related costs	75,159	69,429
Accrued clinical trial expense	45,384	23,654
Accrued sales-related charges, deductions and royalties	114,408	66,855
Other accrued expenses and liabilities	55,683	29,022
Accounts payable and accrued expenses	$ 337,976	$ 250,896