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Collaboration Agreements (Avalanche Biotechnologies, Inc.) (Details) (USD $)
9 Months Ended 1 Months Ended 7 Months Ended 9 Months Ended
Sep. 30, 2014
Sep. 30, 2013
Jul. 31, 2014
Collaboration Agreement with Avalanche Biotechnologies, inc.
Jul. 31, 2014
Collaboration Agreement with Avalanche Biotechnologies, inc.
Sep. 30, 2014
Collaboration Agreement with Avalanche Biotechnologies, inc.
Sep. 30, 2014
Per Product
Collaboration Agreement with Avalanche Biotechnologies, inc.
Collaboration Agreement [Line Items]            
Research and Development Asset Acquired Other than Through Business Combination, Written-off         $ 2,000,000  
Pre-payment of collaboration research costs         6,000,000  
Potential future milestone payments         640,000,000 80,000,000
Number of therapeutic targets         8  
Payment to acquire preferred share of non-public entity         5,000,000  
Number of therapeutic targets of Avalanche's choice         2  
Payments to Acquire Marketable Securities $ 478,436,000 $ 477,312,000   $ 10,000,000    
Number of shares of Common Stock to be purchased     588,235