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Net Product Sales (Details) (USD $)
In Thousands, unless otherwise specified
3 Months Ended 6 Months Ended
Jun. 30, 2014
Jun. 30, 2013
Jun. 30, 2014
Jun. 30, 2013
Dec. 31, 2013
Revenue Disclosure [Line Items]          
Net product sales $ 418,022 $ 333,893 $ 780,400 $ 652,633  
Activity of Sales Related Deductions [Roll Forward]          
Balance 25,082   25,082   24,601
Provision related to current period sales     51,841    
Credits/payments     (51,360)    
Rebates and Chargebacks
         
Activity of Sales Related Deductions [Roll Forward]          
Balance 4,140   4,140   4,400
Provision related to current period sales     14,817    
Credits/payments     (15,077)    
Distribution Related Fees
         
Activity of Sales Related Deductions [Roll Forward]          
Balance 20,420   20,420   19,663
Provision related to current period sales     36,206    
Credits/payments     (35,449)    
Other Sales Related Deductions
         
Activity of Sales Related Deductions [Roll Forward]          
Balance 522   522   538
Provision related to current period sales     818    
Credits/payments     (834)    
Customer concentration risk | Gross Sales Revenue
         
Risks and Uncertainties [Abstract]          
Concentration risk, percentage 73.00% 76.00% 76.00% 77.00%  
EYLEA
         
Revenue Disclosure [Line Items]          
Net product sales 414,800 329,800 773,800 643,700  
ARCALYST
         
Revenue Disclosure [Line Items]          
Net product sales $ 3,200 $ 4,100 $ 6,600 $ 8,900