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Collaboration and Contract Research Agreements (Details) (USD $)
3 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended 1 Months Ended 12 Months Ended 3 Months Ended 12 Months Ended
Dec. 31, 2013
Sep. 30, 2013
Dec. 31, 2012
Sep. 30, 2012
Dec. 31, 2013
Dec. 31, 2012
Dec. 31, 2011
Jan. 31, 2006
ZALTRAP Agreement
Jan. 31, 2005
ZALTRAP Agreement
Sep. 30, 2003
ZALTRAP Agreement
Dec. 31, 2013
ZALTRAP Agreement
Dec. 31, 2012
ZALTRAP Agreement
Dec. 31, 2011
ZALTRAP Agreement
Nov. 30, 2007
Antibody Collaboration
Dec. 31, 2013
Antibody Collaboration
family
antibody
Dec. 31, 2012
Antibody Collaboration
Dec. 31, 2011
Antibody Collaboration
Nov. 30, 2009
Antibody Collaboration
Dec. 31, 2013
VelociGene Agreement
Dec. 31, 2013
Collaboration Agreement with Sanofi
Dec. 31, 2012
Collaboration Agreement with Sanofi
Dec. 31, 2011
Collaboration Agreement with Sanofi
Mar. 31, 2014
PDGFR-beta
Jun. 30, 2013
PDGFR-beta
Dec. 31, 2013
PDGFR-beta
Jun. 30, 2013
Ang2
Dec. 31, 2013
Ang2
Aug. 31, 2007
Bayer Collaboration Agreement - EYLEA outside the US
Oct. 31, 2006
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2012
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2011
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2010
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2009
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2007
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
Marketing approval
Dec. 31, 2012
Bayer Collaboration Agreement - EYLEA outside the US
Marketing approval
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
Pricing approval
Dec. 31, 2012
Bayer Collaboration Agreement - EYLEA outside the US
Pricing approval
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
sales achievement - 1st tier
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
sales achievement - 2nd tier
Dec. 31, 2013
Bayer Collaboration Agreement - EYLEA outside the US
sales achievement - 3rd tier
Mar. 31, 2014
Bayer Collaboration Agreement - PDGFR-beta outside the US
Jan. 31, 2014
Bayer Collaboration Agreement - PDGFR-beta outside the US
Dec. 31, 2013
ex US
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2013
Maximum
Bayer Collaboration Agreement - EYLEA outside the US
Dec. 31, 2013
Minimum
Bayer Collaboration Agreement - EYLEA outside the US
Research and Development Arrangement, Contract to Perform for Others [Line Items]                                                                                              
Total number of shares owned by the collaborator                                       15,816,953                                                      
Company-incurred expenses associated with Sanofi collaborations                                       $ 600,100,000 $ 405,800,000 $ 318,200,000                                                  
Amount of non-refundable payment received for collaboration agreement                 25,000,000                                       75,000,000                                    
Number of shares of Common Stock purchased                   2,799,552                                                                          
Cash price of newly issued, unregistered shares of Common Stock purchased                   45,000,000                                                                          
Royalty based on percentage of annual sales in Japan                     35.00%                                                                        
Maximum amount of substantive milestone payments that may be received relating to marketing approvals                     350,000,000                                                               20,000,000        
Percentage of development expenses to be reimbursed due to profitability of collaboration agreement                     50.00%       50.00%                             50.00%                                  
Development expenses incurred to date                     446,000,000       879,000,000                             276,000,000                                  
Minimum advance notice required to terminate collaboration agreement                     12 months       3 months                                                             12 months 6 months
Regeneron's share of losses in connection with commercialization of products by our collaborator                     (30,810,000) (25,634,000) (9,321,000)                                 101,494,000 0 0                              
Milestone payment 25,000,000 45,000,000 10,000,000 65,000,000             0 50,000,000 0                             20,000,000   70,000,000 25,000,000 0 10,000,000 20,000,000   15,000,000 15,000,000 10,000,000 10,000,000 15,000,000 15,000,000 15,000,000          
Percentage of development cost for the territory outside the United States to be reimbursed due to collaboration agreement                                                                                     25.00%        
Number of sales milestones                                                           3                                  
Starting specified levels of annual sales at which sales milestone payments maybe received -1st tier                                                                               200,000,000         200,000,000    
Royalty rate minimum                                                           33.50%                                  
Royalty rate maximum                                                           40.00%                                  
Starting specified levels of annual sales at which sales milestone payments maybe received - 2nd tier                                                                                 300,000,000            
Starting specified levels of annual sales at which sales milestone payments may be received - 3rd tier                                                                                   400,000,000          
Reimbursement of Regeneron research and development and other expenses                     5,639,000 10,702,000 16,871,000   453,489,000 365,245,000 299,281,000                         20,905,000 34,892,000 33,682,000                              
Up-front payments made to acquire full rights to antibodies                             20,000,000 0 0             (10,000,000)   (10,000,000)                                          
Other Research and Development Expense                                             5,000,000                                                
Substantive Milestone Payments                                                 35,000,000   5,000,000                                        
Other collaboration revenue                     9,682,000 13,268,000 9,932,000   12,111,000 10,233,000 9,846,000                         27,890,000 10,207,000 9,390,000                              
Collaboration revenue         430,111,000 423,814,000 326,609,000       (15,489,000) 48,336,000 17,482,000   445,600,000 375,478,000 309,127,000                                                            
Accounts receivable from Sanofi 104,707,000   99,913,000   104,707,000 99,913,000                 106,100,000 102,600,000                                                              
Expenses under the collaboration payable to collaborating party                     1,400,000 2,700,000                                                                      
Deferred revenue                     18,200,000 14,800,000     71,200,000 78,700,000                           36,400,000 36,500,000                                
Other Collaboration Revenue         220,289,000 70,099,000 43,072,000                                             220,289,000 70,099,000 43,072,000                              
Annual funding maximum of research activities per amended agreement                                   160,000,000                                                          
Additional years to extend the agreement                             3 years                                                                
Substantive milestone payment to the Company                             10,000,000                                                                
Number of therapeutic antibodies currently under development                             7                                                                
Percentage of Trial Costs borne by collaborating party                             80.00%                                                                
Percentage of Trial Costs borne by entity                             20.00%                                                                
Percentage of trial costs to be reimbursed due to profitability of agreement                             30.00%                                                                
Excess Share of profit not required to to be applied to reimburse development cost                             10.00%                                                                
Starting share of profits outside the United States, based on sales, for collaborating party                             65.00%                                                                
Starting share of profits outside the United States, based on sales, for Company                             35.00%                                                                
Ending share of profits outside the United States, based on sales, for collaborating party                             55.00%                                                                
Ending share of profits outside the United States, based on sales, for Company                             45.00%                                                                
Share of losses outside the United States, for collaborating party                             55.00%                                                                
Share of losses outside the United States, for Company                             45.00%                                                                
Maximum amount of milestone payments that may be received if certain sales are achieved                             250,000,000                                                                
Amount of funding of agreed-upon cost incurred to expand manufacturing capacity                             30,000,000                                                                
Period of notice to opt-out of further development and/or commercialization                             12 months                                                                
Period of notice to opt-out of further development upon entering of joint development product                             30 days                                                                
Minimum payments expected to be received under the agreement                                     21,500,000                                                        
Proceeds from Collaborators               25,000,000 25,000,000 80,000,000       85,000,000                 2,500,000           75,000,000           20,000,000               25,500,000        
Number of families of novel antibodies                             2                                                                
Maximum amount of sales milestone payments if total sales achieve specific levels                                                           90,000,000                             30,000,000    
Starting specified levels of annual sales at which sales milestone payments may be received                             1,000,000,000                                                                
Period for Achieving Sales Target for Milestone Payment, Rolling Basis                             12 months                             12 months                                  
Maximum levels of annual sales for which sales milestone payments may be received                                                           1,000,000,000                                  
Additional research and development expenses obligated to reimburse                             17,600,000                             15,300,000 21,900,000 47,800,000                              
Account Receivable from Bayer HealthCare                                                           63,200,000 2,800,000                                
Percentage of global development cost to be reimbursed due to collaboration agreement                                                                                     50.00%        
Opt-in payment                                                                                     20,000,000        
Future development milestone payments                                                                                     17,500,000        
Maximum percentage of outstanding shares that may be acquired, under 'standstill' provisions                                                                                       20.00%      
Amount of Milestone payments earned                                                               $ 10,000,000