Property, Plant, and Equipment (Tables)

12 Months Ended

Dec. 31, 2013

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

Property, plant, and equipment consist of the following:

	As of December 31,
	2013			2012
Land	$	2,768		$	2,117
Building and improvements	343,363			328,173
Leasehold improvements	26,370			10,576
Construction-in-progress	142,370			25,076
Laboratory and other equipment	189,543			159,026
Furniture, computer and office equipment, and other	44,186			35,485
	748,600			560,453
Less, accumulated depreciation and amortization	(221,617		)	(180,513		)
	$	526,983		$	379,940