Property, Plant, and Equipment

12 Months Ended

Dec. 31, 2013

Property, Plant and Equipment [Abstract]

Property, Plant and Equipment

Property, Plant, and Equipment

Property, plant, and equipment consist of the following:

	As of December 31,
	2013			2012
Land	$	2,768		$	2,117
Building and improvements	343,363			328,173
Leasehold improvements	26,370			10,576
Construction-in-progress	142,370			25,076
Laboratory and other equipment	189,543			159,026
Furniture, computer and office equipment, and other	44,186			35,485
	748,600			560,453
Less, accumulated depreciation and amortization	(221,617		)	(180,513		)
	$	526,983		$	379,940

Depreciation and amortization expense on property, plant, and equipment amounted to $41.2 million, $36.9 million, and $31.1 million for the years ended December 31, 2013, 2012, and 2011, respectively. In addition, during 2013 and 2012, the Company incurred non-cash charges of $0.5 million and $2.8 million, respectively, in connection with disposals and retirements of fixed assets. There were no material non-cash charges in connection with disposals and retirements of fixed assets in 2011.

Included in property, plant, and equipment at December 31, 2013 and December 31, 2012 were $0.7 million and $3.6 million of leased equipment under capital leases, respectively, and related accumulated amortization was $0.2 million and $1.1 million at December 31, 2013 and December 31, 2012, respectively.

Property, plant, and equipment at December 31, 2013 and 2012 included $111.1 million and $86.2 million, respectively, of costs incurred by the Company's landlord to construct laboratory and office facilities in Tarrytown, New York. See Note 13a.