Accounts Payable and Accrued Expenses (Details) (USD $)	Sep. 30, 2013	Dec. 31, 2012	Sep. 30, 2012	Dec. 31, 2011
Accounts Payable and Accrued Liabilities, Current [Abstract]
Accounts payable	$ 31,194,000	$ 38,934,000
Accrued payroll and related costs	68,928,000	19,987,000
Accrued clinical trial expense	24,407,000	10,985,000
Accrued sales-related charges, deductions, and royalties	56,290,000	21,870,000
Other accrued expenses and liabilities	38,319,000	19,569,000
Accounts payable and accrued expenses	219,138,000	111,345,000
Accrued Capital Expenditures	$ 18,400,000	$ 8,600,000	$ 7,000,000	$ 6,200,000