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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0001237899-05-000011.txt : 20050107
<SEC-HEADER>0001237899-05-000011.hdr.sgml : 20050107
<ACCEPTANCE-DATETIME>20050107151456
ACCESSION NUMBER:		0001237899-05-000011
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050105
FILED AS OF DATE:		20050107
DATE AS OF CHANGE:		20050107

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			KOLINSKI STUART
		CENTRAL INDEX KEY:			0001226686

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-19034
		FILM NUMBER:		05518142

	BUSINESS ADDRESS:	
		STREET 1:		REGENERON PHARMACEUTICALS INC
		STREET 2:		777 OLD SAW MILL RIVER
		CITY:			TARRYTOWN
		STATE:			NY
		ZIP:			10591

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			REGENERON PHARMACEUTICALS INC
		CENTRAL INDEX KEY:			0000872589
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				133444607
		STATE OF INCORPORATION:			NY
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		777 OLD SAW MILL RIVER RD
		CITY:			TARRYTOWN
		STATE:			NY
		ZIP:			10591-6707
		BUSINESS PHONE:		9143477000
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

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    <periodOfReport>2005-01-05</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000872589</issuerCik>
        <issuerName>REGENERON PHARMACEUTICALS INC</issuerName>
        <issuerTradingSymbol>REGN</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001226686</rptOwnerCik>
            <rptOwnerName>KOLINSKI STUART</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>777 OLD SAW MILL RIVER ROAD</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>TARRYTOWN</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10591</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>VP, Gen Counsel &amp; Secretary</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
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            <securityTitle>
                <value>Incentive Stock Option (right to buy)</value>
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            <conversionOrExercisePrice>
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            <transactionDate>
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        <derivativeTransaction>
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        <derivativeTransaction>
            <securityTitle>
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            <conversionOrExercisePrice>
                <value>37.78</value>
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            <transactionDate>
                <value>2005-01-05</value>
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            <transactionCoding>
                <transactionFormType>4</transactionFormType>
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            <transactionAmounts>
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                <transactionPricePerShare>
                    <value>0</value>
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            <exerciseDate>
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            <expirationDate>
                <value>2010-12-21</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>5000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>0</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The stock option award (combined incentive stock option and non-qualified stock option) vests in four equal annual installments, commencing one year after the date of grant.</footnote>
        <footnote id="F2">The stock option award (combined incentive stock option and non-qualified stock option) was originally granted on December 20, 2002 and vests in four equal annual installments, commencing one year after the date of grant.</footnote>
        <footnote id="F3">The stock option award (combined incentive stock option and non-qualified stock option) was originally granted on September 18, 2000 and vests in five equal annual installments, commencing one year after the date of grant.</footnote>
        <footnote id="F4">The stock option award (combined incentive stock option and non-qualified stock option) was originally granted on December 18, 2001 and vests in four equal annual installments, commencing one year after the date of grant.</footnote>
        <footnote id="F5">The stock option award (combined incentive stock option and non-qualified stock option) was originally granted on December 21, 2000 and vests in five equal annual installments, commencing one year after the date of grant.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/**Stuart Kolinski</signatureName>
        <signatureDate>2005-01-07</signatureDate>
    </ownerSignature>
</ownershipDocument>

</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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