CONDENSED BALANCE SHEETS (Unaudited) (USD $) In Thousands, unless otherwise specified	Jun. 30, 2012	Dec. 31, 2011
Current assets:
Cash and cash equivalents	$ 171,943	$ 483,610
Marketable securities	129,079	43,332
Accounts receivable - trade, net	349,645	28,254
Accounts receivable from Sanofi	85,735	74,781
Prepaid expenses and other current assets	32,791	22,898
Total current assets	769,193	652,875
Restricted cash and marketable securities	8,141	7,721
Marketable securities	288,321	275,887
Property, plant, and equipment, at cost, net of accumulated depreciation and amortization	372,278	367,955
Other assets	19,567	19,145
Total assets	1,457,500	1,323,583
Current liabilities:
Accounts payable and accrued expenses	126,768	95,625
Deferred revenue from Sanofi, current portion	21,790	20,011
Deferred revenue - other, current portion	33,479	31,629
Facility lease obligations, current portion	1,183	1,006
Total current liabilities	183,220	148,271
Deferred revenue from Sanofi	78,281	86,017
Deferred revenue - other	149,031	162,593
Facility lease obligations	159,558	159,508
Convertible senior notes	285,491	275,019
Other long term liabilities	7,262	6,443
Total liabilities	862,843	837,851
Commitments and contingencies
Stockholders' equity:
Preferred stock	0	0
Common Stock	94	91
Additional paid-in capital	1,775,861	1,754,824
Accumulated deficit	(1,178,929)	(1,267,323)
Accumulated other comprehensive loss	(2,371)	(1,862)
Total stockholders' equity	594,657	485,732
Total liabilities and stockholders' equity	1,457,500	1,323,583
Class A Stock [Member]
Stockholders' equity:
Common Stock	$ 2	$ 2