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Property, Plant, and Equipment (Tables)
12 Months Ended
Dec. 31, 2011
Property, Plant, and Equipment [Abstract]  
Property, Plant, and Equipment
Property, plant, and equipment as of December 31, 2011 and 2010 consist of the following:

 
2011
2010
Land
   $2,117
   $2,117
Building and improvements
322,753
242,035
Leasehold improvements
4,479
4,063
Construction-in-progress
10,880
70,356
Laboratory and other equipment
156,397
137,951
Furniture, computer and office equipment, and other
29,468
22,235
 
526,094
478,757
Less, accumulated depreciation and amortization
(158,139)
(131,307)
 
$367,955
$347,450