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Stock-Based Compensation (Details Textual) (USD $)
3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 3 Months Ended 9 Months Ended 0 Months Ended 9 Months Ended 0 Months Ended 9 Months Ended 0 Months Ended 3 Months Ended 9 Months Ended
Sep. 30, 2013
Sep. 30, 2012
Sep. 30, 2013
Plans
Sep. 30, 2012
Dec. 31, 2012
Sep. 30, 2012
Board Member [Member]
Sep. 30, 2012
Board Member [Member]
Sep. 30, 2012
Employees [Member]
Sep. 30, 2012
Employees [Member]
May 06, 2013
Stock Options [Member]
Sep. 30, 2013
Stock Options [Member]
Apr. 04, 2013
Warrant [Member]
Dec. 03, 2010
Warrant [Member]
Sep. 30, 2013
Warrant [Member]
Sep. 30, 2013
1998 Non-Officer Stock Option Plan [Member]
Sep. 30, 2013
1998 Non-Officer Stock Option Plan [Member]
Minimum [Member]
Sep. 30, 2013
1998 Non-Officer Stock Option Plan [Member]
Maximum [Member]
Sep. 30, 2013
2006 Equity Incentive Plan [Member]
Sep. 30, 2013
2006 Equity Incentive Plan [Member]
Minimum [Member]
Sep. 30, 2013
2006 Equity Incentive Plan [Member]
Maximum [Member]
Sep. 30, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Sep. 30, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Minimum [Member]
Sep. 30, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Maximum [Member]
Sep. 12, 2011
Three Year Stock Purchase Warrants [Member]
Sep. 30, 2013
Three Year Stock Purchase Warrants [Member]
Sep. 30, 2012
Three Year Stock Purchase Warrants [Member]
Sep. 30, 2013
Three Year Stock Purchase Warrants [Member]
Sep. 30, 2012
Three Year Stock Purchase Warrants [Member]
Stock-Based Compensation (Textual)                                                        
Stock option expiration date                             June 2008           March 2011              
Options outstanding, vested and expected to vest, outstanding, number                     1,644,583                                  
Options outstanding, vested and expected to vest, aggregate intrinsic value $ 524,000   $ 524,000               $ 3,200,000                                  
Additional common stock authorized for issuance as incentive stock options                   2,000,000                                    
Common stock issued upon exercise of warrants, value                     409,000                                  
Common stock issued upon exercise of warrants, Shares                     (182,361)     (3,871,063)                            
Stock option vesting period     7 years 7 years                       1 year 4 years   1 year 4 years   1 year 4 years          
Stock option expiration period                             10 years     10 years       5 years 7 years          
Warrant issued in period                         120,000                     20,000        
Exercise price of warrants per share                         $ 1.63                     $ 3.90        
Fair value of warrants                         198,000 166,000                   75,000        
Amortized period of warrants                         24 months                     24 months        
Compensation expense related to the vesting of stock options 700,000 690,000 1,900,000 2,900,000                   25,000                            
Fair value of warrants granted included in product research and development expenses                                                 6,000 9,000 25,000 28,000
Additional cash exercise price per share                       $ 1.00                                
Proceeds from exercise of warrants     699,000 155,000               40,000                                
Warrants exercised to purchase common stock                       40,000                                
Subscription receivable 286,000   286,000                286,000                                  
Stock options vesting period description     The options have a 7-year life and 1/3 of the options are vested on the one year anniversary date of grant with the remaining to vest monthly over the remaining 24-months The options have a 7-year life and 1/3 of the options are vested on the one year anniversary date of grant with the remaining to vest monthly over the remaining 24-months                                                
Number of equity incentive plans     2                                                  
Number of non-employee director stock option plan     1                                                  
Options granted to purchase of common stock to employee     130,000     0 360,000 45,000 1,145,000                                      
Stock options, grant date fair value     $ 682,500                                                  
Recognition period of unamortized expense related to stock options and warrants     1 year 7 months 6 days                                                  
Stock options exercise 62,350   62,350