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Stock-Based Compensation (Details Textual) (USD $)
0 Months Ended 3 Months Ended 0 Months Ended 3 Months Ended 0 Months Ended 3 Months Ended 0 Months Ended 3 Months Ended
Mar. 16, 2012
Mar. 31, 2013
Plan
Mar. 31, 2012
Mar. 11, 2013
Stock Options [Member]
Mar. 31, 2013
Stock Options [Member]
Mar. 19, 2013
Stock Options [Member]
Dec. 03, 2010
Warrant [Member]
Mar. 31, 2013
Warrant [Member]
Mar. 31, 2012
Warrant [Member]
Mar. 31, 2013
1998 Non-Officer Stock Option Plan [Member]
Mar. 31, 2013
1998 Non-Officer Stock Option Plan [Member]
Minimum [Member]
Mar. 31, 2013
1998 Non-Officer Stock Option Plan [Member]
Maximum [Member]
Mar. 31, 2013
2006 Equity Incentive Plan [Member]
Mar. 31, 2013
2006 Equity Incentive Plan [Member]
Minimum [Member]
Mar. 31, 2013
2006 Equity Incentive Plan [Member]
Maximum [Member]
Mar. 31, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Mar. 31, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Minimum [Member]
Mar. 31, 2013
2001 Non-Employee Director Stock Option Plan [Member]
Maximum [Member]
Sep. 12, 2011
Three Year Stock Purchase Warrants [Member]
Mar. 31, 2013
Three Year Stock Purchase Warrants [Member]
Mar. 31, 2012
Three Year Stock Purchase Warrants [Member]
Stock-Based Compensation (Textual)                                          
Stock option expiration date                   June 2008           March 2011          
Options outstanding, vested and expected to vest, outstanding, number         1,691,544                                
Options outstanding, vested and expected to vest, aggregate intrinsic value         $ 2,400,000                                
Additional common stock authorized for issuance as incentive stock options       2,000,000                                  
Common stock issued upon exercise of warrants, value       167,000                                  
Common stock issued upon exercise of warrants, Shares       38,456 (38,456)     (590,094)                          
Intrinsic value related to options exercised           58,000,000                              
Stock option vesting period                     1 year 4 years   1 year 4 years   1 year 4 years      
Stock option expiration period                   10 years     10 years       5 years 7 years      
Warrant issued in period             120,000                       20,000    
Exercise price of warrants per share             $ 1.63                       $ 3.90    
Fair value of warrants             198,000                       75,000    
Amortized period of warrants             24 months                            
Compensation expense related to the vesting of stock options   576,000 0           25,000                        
Fair value of warrants granted included in product research and development expenses                                       $ 10,000 $ 9,000
Number of equity incentive plans   2                                      
Number of non-employee director stock option plan   1                                      
Options granted to purchase of common stock to employee   15,000                                       
Stock options, grant date fair value   $ 80,000                                      
Recognition period of unamortized expense related to stock options and warrants   3 years                                      
Common stock purchase due to exercise of warrant by warrant holders excluding CFO     270,094                                    
Common stock received due to net exercise provision of warrant 266,228   198,512                                    
Common stock purchase due to exercise of warrant by CFO 320,000