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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 KUe76Mqm4XBbv/IaDM779DGolmipmfeZwmilqARZYYRA4stKNYFj2P2WGFcKsbP6
 /hHCtRDNlwXaNFd3PV1vjw==

<SEC-DOCUMENT>0000086115-09-000042.txt : 20090918
<SEC-HEADER>0000086115-09-000042.hdr.sgml : 20090918
<ACCEPTANCE-DATETIME>20090918134253
ACCESSION NUMBER:		0000086115-09-000042
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20090918
FILED AS OF DATE:		20090918
DATE AS OF CHANGE:		20090918

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CLARIENT, INC
		CENTRAL INDEX KEY:			0001038223
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-MEDICAL LABORATORIES [8071]
		IRS NUMBER:				752649072
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		31 COLUMBIA
		CITY:			ALISO VIEJO
		STATE:			CA
		ZIP:			92656
		BUSINESS PHONE:		949 425-5865

	MAIL ADDRESS:	
		STREET 1:		31 COLUMBIA
		CITY:			ALISO VIEJO
		STATE:			CA
		ZIP:			92656

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	CHROMAVISION MEDICAL SYSTEMS INC
		DATE OF NAME CHANGE:	19970423

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SAFEGUARD SCIENTIFICS INC
		CENTRAL INDEX KEY:			0000086115
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-BUSINESS SERVICES, NEC [7389]
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22677
		FILM NUMBER:		091076397

	BUSINESS ADDRESS:	
		STREET 1:		435 DEVON PARK DR
		STREET 2:		BLDG 800
		CITY:			WAYNE
		STATE:			PA
		ZIP:			19087
		BUSINESS PHONE:		6102930600

	MAIL ADDRESS:	
		STREET 1:		435 DEVON PARK DR
		STREET 2:		BLDG 800
		CITY:			WAYNE
		STATE:			PA
		ZIP:			19087

	FORMER NAME:	
		FORMER CONFORMED NAME:	SAFEGUARD INDUSTRIES INC
		DATE OF NAME CHANGE:	19810525

	FORMER NAME:	
		FORMER CONFORMED NAME:	SAFEGUARD CORP
		DATE OF NAME CHANGE:	19690521
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-09-18</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001038223</issuerCik>
        <issuerName>CLARIENT, INC</issuerName>
        <issuerTradingSymbol>CLRT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000086115</rptOwnerCik>
            <rptOwnerName>SAFEGUARD SCIENTIFICS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>435 DEVON PARK DRIVE</rptOwnerStreet1>
            <rptOwnerStreet2>BUILDING 800</rptOwnerStreet2>
            <rptOwnerCity>WAYNE</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19087-1945</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2009-09-18</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>S</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2400000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>3.5</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>D</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>28133821</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>SSI Delaware</value>
                    <footnoteId id="F1"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Safeguard Delaware, Inc. (&quot;SSI Delaware&quot;) is a wholly owned subsidiary of reporting person and the record holder of the Issuer's securities.</footnote>
    </footnotes>

    <remarks>Additional Reporting Person, which is a wholly owned subsidiary of reporting person:

Safeguard Delaware, Inc.
1105 North Market Street
Wilmington, DE 19801</remarks>

    <ownerSignature>
        <signatureName>By: BRIAN J. SISKO, SVP &amp; GENERAL COUNSEL  For: SAFEGUARD SCIENTIFICS, INC.</signatureName>
        <signatureDate>2009-09-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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