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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 MuaZJ+C8gWoH+X1k6gkF+nExDTnIWWo7w6HxrbzIfRtKiZ1cKueTaOvd9YGFmTJ/
 UZRaDgbWQN/iktyggGUzLQ==

<SEC-DOCUMENT>0000086115-05-000007.txt : 20050802
<SEC-HEADER>0000086115-05-000007.hdr.sgml : 20050802
<ACCEPTANCE-DATETIME>20050802165838
ACCESSION NUMBER:		0000086115-05-000007
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20050801
FILED AS OF DATE:		20050802
DATE AS OF CHANGE:		20050802

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CHROMAVISION MEDICAL SYSTEMS INC
		CENTRAL INDEX KEY:			0001038223
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				752649072
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		33171 PASEO CORVEZA
		CITY:			SAN JUAN CAPISTRANO
		STATE:			CA
		ZIP:			92675
		BUSINESS PHONE:		9494433355

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			SAFEGUARD SCIENTIFICS INC
		CENTRAL INDEX KEY:			0000086115
		STANDARD INDUSTRIAL CLASSIFICATION:	SERVICES-BUSINESS SERVICES, NEC [7389]
		STATE OF INCORPORATION:			PA
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-22677
		FILM NUMBER:		05992688

	BUSINESS ADDRESS:	
		STREET 1:		435 DEVON PARK DR
		STREET 2:		800 THE SAFEGUARD BLDG
		CITY:			WAYNE
		STATE:			PA
		ZIP:			19087
		BUSINESS PHONE:		6102930600

	MAIL ADDRESS:	
		STREET 1:		435 DEVON PARK DR
		STREET 2:		BLDG 800
		CITY:			WAYNE
		STATE:			PA
		ZIP:			19087

	FORMER NAME:	
		FORMER CONFORMED NAME:	SAFEGUARD INDUSTRIES INC
		DATE OF NAME CHANGE:	19810525

	FORMER NAME:	
		FORMER CONFORMED NAME:	SAFEGUARD CORP
		DATE OF NAME CHANGE:	19690521
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>edgardoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2005-08-01</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001038223</issuerCik>
        <issuerName>CHROMAVISION MEDICAL SYSTEMS INC</issuerName>
        <issuerTradingSymbol>CLRT</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000086115</rptOwnerCik>
            <rptOwnerName>SAFEGUARD SCIENTIFICS INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>800 THE SAFEGUARD BUILDING</rptOwnerStreet1>
            <rptOwnerStreet2>435 DEVON PARK DRIVE</rptOwnerStreet2>
            <rptOwnerCity>WAYNE</rptOwnerCity>
            <rptOwnerState>PA</rptOwnerState>
            <rptOwnerZipCode>19087-1945</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeTransaction>
            <securityTitle>
                <value>Warrant (right to buy)</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <value>2</value>
            </conversionOrExercisePrice>
            <transactionDate>
                <value>2005-08-01</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>J</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>50000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0</value>
                    <footnoteId id="F1"/>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <exerciseDate>
                <value>2005-08-01</value>
            </exerciseDate>
            <expirationDate>
                <value>2009-08-01</value>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>50000</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>50000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>SSI Delaware</value>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </derivativeTransaction>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The warrant was issued to Safeguard Delaware, Inc. by Issuer as partial consideration for Safeguard's guaranty of the Issuer's payment obligations under  its loan agreement with Comerica Bank.</footnote>
        <footnote id="F2">Safeguard Delaware, Inc., a wholly owned subsidiary of reporting person, is the record holder of the securities reported herein.</footnote>
    </footnotes>

    <remarks>Additional Reporting Persons:

Safeguard Scientifics (Delaware), Inc.
Safeguard Delaware, Inc.
103 Springer Building
3411 Silverside Road
P. O. Box 7048
Wilmington, DE 19803</remarks>

    <ownerSignature>
        <signatureName>STEVEN J. FEDER</signatureName>
        <signatureDate>2005-08-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
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