-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Vcau2JK78l4UlASeRPyLQty3wGKOTBoMjYVqSUcH3+lJ9+jW7WTV+V1y1miolo9Z pIaRYPH3HHbynSCroyoAwg== 0000950116-97-000274.txt : 19970222 0000950116-97-000274.hdr.sgml : 19970222 ACCESSION NUMBER: 0000950116-97-000274 CONFORMED SUBMISSION TYPE: SC 13G PUBLIC DOCUMENT COUNT: 1 FILED AS OF DATE: 19970214 SROS: NONE GROUP MEMBERS: HAROLD R. WERNER GROUP MEMBERS: HEALTHCARE PARTNERS II, L.P. GROUP MEMBERS: HEALTHCARE PARTNERS III, L.P. GROUP MEMBERS: HEALTHCARE PARTNERS IV, L.P. GROUP MEMBERS: HEALTHCARE VENTURES II LP GROUP MEMBERS: HEALTHCARE VENTURES III, L.P. GROUP MEMBERS: HEALTHCARE VENTURES IV, L.P. GROUP MEMBERS: JAMES H. CAVANAUGH, PH.D. GROUP MEMBERS: JOHN W. LITTLECHILD GROUP MEMBERS: WILLIAM CROUSE SUBJECT COMPANY: COMPANY DATA: COMPANY CONFORMED NAME: VIRUS RESEARCH INSTITUTE INC CENTRAL INDEX KEY: 0000902010 STANDARD INDUSTRIAL CLASSIFICATION: BIOLOGICAL PRODUCTS (NO DIAGNOSTIC SUBSTANCES) [2836] IRS NUMBER: 223098869 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G SEC ACT: 1934 Act SEC FILE NUMBER: 005-49497 FILM NUMBER: 97532842 BUSINESS ADDRESS: STREET 1: 61 MOULTON ST CITY: CAMBRIDGE STATE: MA ZIP: 02139 BUSINESS PHONE: 6178646232 MAIL ADDRESS: STREET 1: 61 MOULTON ST CITY: CAMBRIDGE STATE: MA ZIP: 02138 FILED BY: COMPANY DATA: COMPANY CONFORMED NAME: HEALTHCARE VENTURES II LP CENTRAL INDEX KEY: 0000859649 STANDARD INDUSTRIAL CLASSIFICATION: UNKNOWN SIC - 0000 [0000] IRS NUMBER: 223015728 STATE OF INCORPORATION: DE FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: SC 13G BUSINESS ADDRESS: STREET 1: TWIN TOWERS AT METRO PARK STREET 2: 379 THORNALL AVENUE CITY: EDISON STATE: NJ ZIP: 08837 BUSINESS PHONE: 9089064613 MAIL ADDRESS: STREET 1: TWIN TOWERS AT METRO PARK STREET 2: 379 THORNALL AVENUE CITY: EDISON STATE: NJ ZIP: 08837 SC 13G 1 SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 SCHEDULE 13G Under the Securities Exchange Act of 1934 (Amendment No. )* Virus Research Institute, Inc. - -------------------------------------------------------------------------------- (Name of Issuer) Common Stock, $.001 par value - -------------------------------------------------------------------------------- (Title of Class of Securities) 927920108 ---------------------------- (CUSIP Number) Check the following box if a fee is being paid with this statement|X|. (A fee is not required only if the filing person: (1) has a previous statement on file reporting beneficial ownership of more than five percent of the class of securities described in Item 1; and (2) has filed no amendment subsequent thereto reporting beneficial ownership of five percent or less of such class.) (See Rule 13d-7.) * The remainder of this cover page shall be filled out for a reporting person's initial filing on this form with respect to the subject class of securities, and for any subsequent amendment containing information which would alter the disclosures provided in a prior cover page. The information required in the remainder of this cover page shall not be deemed to be "filed" for the purpose of Section 18 of the Securities Exchange Act of 1934 ("Act") or otherwise subject to the liabilities of that section of the Act but shall be subject to all other provisions of the Act (however, see the Notes). (Continued on following page(s)) Page 1 of 16 Pages - ---------------------- -------------------- CUSIP No. 927920108 13G Page 2 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Ventures II, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 1,324,975 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 1,324,975 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,324,975 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 15% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 3 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Partners II, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 1,324,975 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 1,324,975 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,324,975 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 15% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 4 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Ventures III, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 1,174,575 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 1,174,575 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,174,575 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 13.3% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 5 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Partners III, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 1,174,575 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 1,174,575 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 1,174,575 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 13.3% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 6 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Ventures IV, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 344,928 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 344,928 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 344,928 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 4.0% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 7 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON HealthCare Partners IV, L.P. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION Delaware - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 344,928 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 344,928 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 344,928 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 4.0% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* PN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 8 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON James H. Cavanaugh, Ph.D. - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 2,844,478 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 2,844,478 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,844,478 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 32.1% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* IN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 9 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON Harold R. Werner - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 2,844,478 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 2,844,478 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,844,478 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 32.1% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* IN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 10 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON William Crouse - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 2,844,478 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 2,844,478 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,844,478 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 32.1% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* IN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! - ---------------------- -------------------- CUSIP No. 927920108 13G Page 11 of 16 Pages - ---------------------- -------------------- - -------------------------------------------------------------------------------- 1 NAME OF REPORTING PERSON S.S. OR I.R.S. IDENTIFICATION NO. OF ABOVE PERSON John W. Littlechild - -------------------------------------------------------------------------------- 2 CHECK THE APPROPRIATE BOX IF A MEMBER OF A GROUP* (a) |_| (b) |_| - -------------------------------------------------------------------------------- 3 SEC USE ONLY - -------------------------------------------------------------------------------- 4 CITIZENSHIP OR PLACE OF ORGANIZATION United States - -------------------------------------------------------------------------------- NUMBER OF SOLE VOTING POWER SHARES 5 ----------------------------------------------------------- BENEFICIALLY 6 SHARED VOTING POWER OWNED BY 2,844,478 ----------------------------------------------------------- EACH 7 SOLE DISPOSITIVE POWER REPORTING ----------------------------------------------------------- PERSON WITH 8 SHARED DISPOSITIVE POWER 2,844,478 - -------------------------------------------------------------------------------- 9 AGGREGATE AMOUNT BENEFICIALLY OWNED BY EACH REPORTING PERSON 2,844,478 - -------------------------------------------------------------------------------- 10 CHECK BOX IF THE AGGREGATE AMOUNT IN ROW (9) EXCLUDES CERTAIN SHARES* |_| - -------------------------------------------------------------------------------- 11 PERCENTAGE CLASS REPRESENTED BY AMOUNT IN ROW 9 32.1% - -------------------------------------------------------------------------------- 12 TYPE OF REPORTING PERSON* IN - -------------------------------------------------------------------------------- *SEE INSTRUCTIONS BEFORE FILLING OUT! Page 12 of 16 Item 1. (a) Name of Issuer: Virus Research Institute, Inc. (b) Address of Issuer's Principal Executive Offices: 61 Moulton Street Cambridge, Massachusetts 02138 Item 2. (a) Name of Person Filing: HealthCare Ventures II, L.P. ("HCV II"), HealthCare Partners II, L.P. ("HCP II"), HealthCare Ventures III, L.P. ("HCV III"), HealthCare Partners III, L.P. ("HCP III"), HealthCare Ventures IV, L.P. ("HCV IV"), HealthCare Partners IV, L.P. ("HCP IV"), Dr. Cavanaugh and Messrs. Werner, Littlechild, and Crouse. See attached Exhibit A which is a copy of their agreement in writing to file this statement on behalf of each of them.1 (b) Address of Principal Business Office or, if none, Residence: The business address for HCV II, HCP II, HCV III, HCP III, HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner and Crouse is Twin Towers at Metro Park, 379 Thornall Street, Edison, New Jersey 08837. The business address for Mr. Littlechild is One Kendall Square, Building 300, Cambridge, Massachusetts 02139. (c) Citizenship: HCV II, HCP II, HCV III, HCP III, HCV IV and HCP IV are limited partnerships organized under the laws of the State of Delaware. Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are each United States citizens. (d) Title of Class of Securities: Common Stock, par value $.001 ("Shares"). - -------- 1 Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse are general partners of each of HCP II, HCP III and HCP IV, which are the general partner of each of HCV II, HCV III and HCV IV, respectively the record holder of Issuer's securities. Page 13 of 16 (e) CUSIP Number: 927920108 Item 3. If this statement is filed pursuant to Rule 13d-1(b), or 13d-2(b), check whether the person filing is a: Inapplicable. Item 4. Ownership. (a) Amount Beneficially Owned: As of December 31, 1996: HCV II and HCP II beneficially owned 1,324,975 Shares of Issuer's Common Stock; HCV III and HCP III beneficially owned 1,174,575 Shares of Issuer's Securities, consisting of 1,131,595 Shares of Issuer's Common Stock and immediately exercisable warrants to purchase 42,980 Shares of Issuer's Common Stock; HCV IV and HCP IV beneficially owned 344,928 Shares of Issuer's Securities, consisting of 332,306 Shares of Issuer's Common Stock and immediately exercisable warrants to purchase 12,622 Shares of Issuer's Common Stock; and Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse beneficially owned 2,844,478 Shares of Issuer's Securities, consisting of 2,788,876 Shares of Issuer's Common Stock and immediately exercisable warrants to purchase 55,602 Shares of Issuer's Common Stock. (b) Percent of Class: As of December 31, 1996: the 1,131,595 Shares of Issuer's Securities beneficially owned by HCV II and HCP II constitute 15% of Issuer's Shares outstanding; the 1,174,575 Shares of Issuer's Securities beneficially owned by HCV III and HCP III constitute 13.3% of the Issuer's Shares outstanding; the 344,928 Shares of Issuer's Securities beneficially owned by HCV IV and HCP IV consisted 4.0% of Issuer's Shares outstanding and the 2,844,478 Shares of Issuer's Securities beneficially owned by Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse constitute 32.1% of Issuer's Shares outstanding. (c) Number of shares as to which such person has: (i) sole power to vote or to direct the vote: Inapplicable (ii) shared power to vote or to direct the vote: HCV II, HCP II, Dr. Cavanaugh and Messrs. Werner, Littlechild, and Crouse share the power to vote or direct the vote of those shares owned by HCV II. Page 14 of 16 HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner, Littlechild, and Crouse share the power to vote or direct the vote of those shares owned by HCV III. HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner, Littlechild, and Crouse share the power to vote or direct the vote of those shares owned by HCV IV. (iii) sole power to dispose or to direct the disposition of: Inapplicable (iv) shared power to dispose of or to direct the disposition of: HCV II, HCP II, Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power to dispose of or direct the disposition of those shares owned by HCV II. HCV III, HCP III, Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power to dispose of or direct the disposition of those shares owned by HCV III. HCV IV, HCP IV, Dr. Cavanaugh and Messrs. Werner, Littlechild and Crouse share the power to dispose of or direct the disposition of those shares owned by HCV IV. Item 5. Ownership of Five Percent or less of a Class: Inapplicable. Item 6. Ownership of More than Five Percent on Behalf of Another Person: Inapplicable. Item 7. Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company: Inapplicable. Item 8. Identification and Classification of Members of the Group: Inapplicable. Item 9. Notice of Dissolution of Group: Inapplicable. Item 10. Certification: Inapplicable. Page 15 of 16 SIGNATURES After reasonable inquiry and to the best of my knowledge and belief, I certify that the information set forth in this statement is true, complete and correct. Dated: February 13, 1997 HealthCare Ventures II, L.P., Edison, New Jersey by its General Partner, HealthCare Partners II, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners II, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Ventures III, L.P., Edison, New Jersey by its General Partner, HealthCare Partners III, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners III, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Ventures IV, L.P., Edison, New Jersey by its General Partner, HealthCare Partners IV, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners IV, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey James H. Cavanaugh, Ph.D. Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey Harold R. Werner Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Cambridge, Massachusetts John W. Littlechild Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey William Crouse
Page 16 of 16 EXHIBIT A AGREEMENT JOINT FILING OF SCHEDULE 13G The undersigned hereby agree to jointly prepare and file with regulatory authorities a Schedule 13G and any future amendments thereto reporting each of the undersigned's ownership of securities of Virus Research Institute, Inc. and hereby affirm that such Schedule 13G is being filed on behalf of each of the undersigned. Dated: February 13, 1997 HealthCare Ventures II, L.P., Edison, New Jersey by its General Partner, HealthCare Partners II, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners II, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Ventures III, L.P., Edison, New Jersey by its General Partner, HealthCare Partners III, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners III, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Ventures IV, L.P., Edison, New Jersey by its General Partner, HealthCare Partners IV, L.P. By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 HealthCare Partners IV, L.P. Edison, New Jersey By: /s/ Jeffrey Steinberg -------------------------------- Administrative Partner Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey James H. Cavanaugh, Ph.D. Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey Harold R. Werner Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Cambridge, Massachusetts John W. Littlechild Dated: February 13, 1997 By: /s/ Jeffrey Steinberg as Attorney-in-Fact -------------------------------- Edison, New Jersey William Crouse
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