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Note 2 - Liquidity and Uncertainties (Details Textual) - USD ($)
3 Months Ended 6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Jun. 30, 2022
Jun. 30, 2021
Dec. 31, 2021
Retained Earnings (Accumulated Deficit), Total $ (112,464,478)   $ (112,464,478)   $ (107,704,274)
Net Income (Loss) Attributable to Parent, Total $ (2,858,481) $ (2,680,468) $ (4,760,204) $ (3,653,337)