Collaboration and License Agreements- CytomX (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020	Nov. 30, 2022	Jun. 30, 2016
Collaborative Agreements disclosures
Revenue from contract with customer	$ 108,782	$ 69,856	$ 132,299
Contract with customer asset gross				$ 125,000
Research and development support
Collaborative Agreements disclosures
Revenue from contract with customer	940	398	28
License and milestone fees
Collaborative Agreements disclosures
Revenue from contract with customer	76,027	$ 22,650	$ 63,742
License and milestone fees | CytomX
Collaborative Agreements disclosures
Revenue from contract with customer	4,000
License and milestone fees | CytomX | Maximum
Collaborative Agreements disclosures
Contract with customer asset gross	$ 355,000
License and milestone fees | CytomX | Sales milestones
Collaborative Agreements disclosures
Contract with customer asset gross					$ 160,000