0001104659-15-074417.txt : 20151030 0001104659-15-074417.hdr.sgml : 20151030 20151030114457 ACCESSION NUMBER: 0001104659-15-074417 CONFORMED SUBMISSION TYPE: 10-Q PUBLIC DOCUMENT COUNT: 10 CONFORMED PERIOD OF REPORT: 20150930 FILED AS OF DATE: 20151030 DATE AS OF CHANGE: 20151030 FILER: COMPANY DATA: COMPANY CONFORMED NAME: IMMUNOGEN INC CENTRAL INDEX KEY: 0000855654 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 042726691 STATE OF INCORPORATION: MA FISCAL YEAR END: 0630 FILING VALUES: FORM TYPE: 10-Q SEC ACT: 1934 Act SEC FILE NUMBER: 000-17999 FILM NUMBER: 151186104 BUSINESS ADDRESS: STREET 1: 830 WINTER ST CITY: WALTHAM STATE: MA ZIP: 02451 BUSINESS PHONE: (781)895-0600 MAIL ADDRESS: STREET 1: 830 WINTER ST CITY: WALTHAM STATE: MA ZIP: 02451 10-Q 1 a15-18859_110q.htm 10-Q

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UNITED STATES

SECURITIES AND EXCHANGE COMMISSION

Washington, D.C. 20549

 

FORM 10-Q

 

x      QUARTERLY REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 

For the quarterly period ended September 30, 2015

 

OR

 

o         TRANSITION REPORT PURSUANT TO SECTION 13 OR 15(d) OF THE SECURITIES EXCHANGE ACT OF 1934

 

For the transition period from            to            

 

Commission file number 0-17999

 

ImmunoGen, Inc.

 

Massachusetts

 

04-2726691

(State or other jurisdiction of incorporation or
organization)

 

(I.R.S. Employer Identification No.)

 

830 Winter Street, Waltham, MA 02451

(Address of principal executive offices, including zip code)

 

(781) 895-0600

(Registrant’s telephone number, including area code)

 

Indicate by check mark whether the registrant (1) has filed all reports required to be filed by Section 13 or 15(d) of the Securities Exchange Act of 1934 during the preceding 12 months (or for such shorter period that the registrant was required to file such reports), and (2) has been subject to such filing requirements for the past 90 days.  xYes o No

 

Indicate by check mark whether the registrant has submitted electronically and posted on its corporate Website, if any, every Interactive Data File required to be submitted and posted pursuant to Rule 405 of Regulation S-T (§232.405 of this chapter) during the preceding 12 months (or for such shorter period that the registrant was required to submit and post such files).  x Yes  o No

 

Indicate by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, or a smaller reporting company. See the definitions of “large accelerated filer,” “accelerated filer” and “smaller reporting company” in Rule 12b-2 of the Exchange Act. (Check one):

 

Large accelerated filer x

 

Accelerated filer o

 

 

 

Non-accelerated filer o
(Do not check if a smaller reporting company)

 

Smaller reporting company o

 

Indicate by check mark whether the registrant is a shell company (as defined in Rule 12b-2 of the Exchange Act).  o Yes  x No

 

Indicate the number of shares outstanding of each of the issuer’s classes of common stock, as of the latest practicable date.

 

Shares of common stock, par value $.01 per share: 86,984,630 shares outstanding as of October 27, 2015.

 

 

 



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IMMUNOGEN, INC.

FORM 10-Q

FOR THE QUARTER ENDED SEPTEMBER 30, 2015

TABLE OF CONTENTS

 

Item

 

 

Page Number

 

 

 

 

Part I

1.

Financial Statements (Unaudited):

 

 

 

 

 

 

1a.

Consolidated Balance Sheets as of September 30, 2015 and June 30, 2015

 

2

 

 

 

 

1b.

Consolidated Statements of Operations and Comprehensive Loss for the three months ended September 30, 2015 and 2014

 

3

 

 

 

 

1c.

Consolidated Statements of Cash Flows for the three months ended September 30, 2015 and 2014

 

4

 

 

 

 

1d.

Notes to Consolidated Financial Statements

 

5

 

 

 

 

2.

Management’s Discussion and Analysis of Financial Condition and Results of Operations

 

17

 

 

 

 

3.

Quantitative and Qualitative Disclosures about Market Risk

 

24

 

 

 

 

4.

Controls and Procedures

 

24

 

 

 

 

Part II

 

 

 

 

1A.

Risk Factors

 

24

 

 

 

 

6.

Exhibits

 

25

 

 

 

 

 

Signatures

 

26

 

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ITEM 1.  Financial Statements

 

IMMUNOGEN, INC.

CONSOLIDATED BALANCE SHEETS

(UNAUDITED)

In thousands, except per share amounts

 

 

 

September 30,
2015

 

June 30,
2015

 

ASSETS

 

 

 

 

 

Cash and cash equivalents

 

$

247,843

 

$

278,109

 

Accounts receivable

 

6,812

 

5,088

 

Unbilled revenue

 

899

 

714

 

Inventory

 

1,246

 

2,935

 

Current portion of deferred financing costs

 

1,136

 

1,159

 

Prepaid and other current assets

 

4,080

 

4,175

 

Total current assets

 

262,016

 

292,180

 

Property and equipment, net of accumulated depreciation

 

18,510

 

16,254

 

Deferred financing costs, net of current portion

 

4,147

 

4,415

 

Other assets

 

911

 

974

 

 

 

 

 

 

 

Total assets

 

$

285,584

 

$

313,823

 

LIABILITIES AND SHAREHOLDERS’ EQUITY

 

 

 

 

 

Accounts payable

 

$

9,689

 

$

8,138

 

Accrued compensation

 

3,262

 

8,346

 

Other accrued liabilities

 

9,631

 

10,441

 

Current portion of deferred lease incentive

 

646

 

646

 

Current portion of liability related to the sale of future royalties

 

11,862

 

7,906

 

Current portion of deferred revenue

 

858

 

333

 

Total current liabilities

 

35,948

 

35,810

 

 

 

 

 

 

 

Deferred lease incentive, net of current portion

 

6,139

 

6,301

 

Deferred revenue, net of current portion

 

40,794

 

40,855

 

Liability related to the sale of future royalties, net of current portion

 

186,967

 

191,756

 

Other long-term liabilities

 

4,127

 

3,997

 

Total liabilities

 

273,975

 

278,719

 

Commitments and contingencies (Note E)

 

 

 

 

 

Shareholders’ equity:

 

 

 

 

 

Preferred stock, $0.01 par value; authorized 5,000 shares; no shares issued and  outstanding

 

 

 

Common stock, $0.01 par value; authorized 150,000 shares; issued and outstanding  86,981 and 86,579 shares as of September 30, 2015 and June 30, 2015, respectively

 

870

 

866

 

Additional paid-in capital

 

753,349

 

743,108

 

Accumulated deficit

 

(742,610

)

(708,870

)

Total shareholders’ equity

 

11,609

 

35,104

 

Total liabilities and shareholders’ equity

 

$

285,584

 

$

313,823

 

 

The accompanying notes are an integral part of the consolidated financial statements.

 

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IMMUNOGEN, INC.

CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS

(UNAUDITED)

In thousands, except per share amounts

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

 

 

 

 

 

 

Revenues:

 

 

 

 

 

License and milestone fees

 

$

6,070

 

$

6,234

 

Royalty revenue

 

 

4,166

 

Non-cash royalty revenue related to the sale of future royalties

 

5,684

 

 

Research and development support

 

772

 

776

 

Clinical materials revenue

 

2,325

 

2,027

 

 

 

 

 

 

 

Total revenues

 

14,851

 

13,203

 

 

 

 

 

 

 

Operating Expenses:

 

 

 

 

 

Research and development

 

35,132

 

28,018

 

General and administrative

 

8,329

 

7,095

 

 

 

 

 

 

 

Total operating expenses

 

43,461

 

35,113

 

 

 

 

 

 

 

Loss from operations

 

(28,610

)

(21, 910

)

 

 

 

 

 

 

Investment income, net

 

51

 

8

 

Non-cash interest expense on liability related to the sale of future royalties

 

(5,143

)

 

Other expense, net

 

(38

)

(380

)

 

 

 

 

 

 

Net loss

 

$

(33,740

)

$

(22,282

)

 

 

 

 

 

 

Basic and diluted net loss per common share

 

$

(0.39

)

$

(0.26

)

 

 

 

 

 

 

Basic and diluted weighted average common shares outstanding

 

86,838

 

85,872

 

Total comprehensive loss

 

$

(33,740

)

$

(22,282

)

 

The accompanying notes are an integral part of the consolidated financial statements.

 

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IMMUNOGEN, INC.

CONSOLIDATED STATEMENTS OF CASH FLOWS

(UNAUDITED)

In thousands, except per share amounts

 

 

 

Three Months ended September 30,

 

 

 

2015

 

2014

 

 

 

 

 

 

 

Cash flows from operating activities:

 

 

 

 

 

Net loss

 

$

(33,740

)

$

(22,282

)

Adjustments to reconcile net loss to net cash used for operating activities:

 

 

 

 

 

Non-cash royalty revenue related to sale of future royalties

 

(5,684

)

 

Non-cash interest expense on liability related to sale of future royalties

 

5,143

 

 

Depreciation and amortization

 

1,127

 

1,389

 

Gain on sale/disposal of fixed assets

 

(6

)

 

Stock and deferred share unit compensation

 

5,783

 

5,410

 

Deferred rent

 

29

 

92

 

Changes in operating assets and liabilities:

 

 

 

 

 

Accounts receivable

 

(1,724

)

58

 

Unbilled revenue

 

(185

)

545

 

Inventory

 

1,689

 

835

 

Prepaid and other current assets

 

95

 

525

 

Other assets

 

62

 

105

 

Accounts payable

 

1,551

 

138

 

Accrued compensation

 

(5,084

)

(3,153

)

Other accrued liabilities

 

(871

)

29

 

Deferred revenue

 

464

 

(2,983

)

Proceeds from landlord for tenant improvements

 

 

393

 

Net cash used for operating activities

 

(31,351

)

(18,899

)

 

 

 

 

 

 

Cash flows from investing activities:

 

 

 

 

 

Purchases of property and equipment

 

(3,377

)

(1,708

)

Net cash used for investing activities

 

(3,377

)

(1,708

)

 

 

 

 

 

 

Cash flows from financing activities:

 

 

 

 

 

Proceeds from stock options exercised

 

4,462

 

144

 

Net cash provided by financing activities

 

4,462

 

144

 

 

 

 

 

 

 

Net change in cash and cash equivalents

 

(30,266

)

(20,463

)

 

 

 

 

 

 

Cash and cash equivalents, beginning balance

 

278,109

 

142,261

 

 

 

 

 

 

 

Cash and cash equivalents, ending balance

 

$

247,843

 

$

121,798

 

 

The accompanying notes are an integral part of the consolidated financial statements.

 

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IMMUNOGEN, INC.

NOTES TO CONSOLIDATED FINANCIAL STATEMENTS

September 30, 2015

 

A.                                    Summary of Significant Accounting Policies

 

Basis of Presentation

 

The accompanying unaudited consolidated financial statements at September 30, 2015 and June 30, 2015 and for the three months ended September 30, 2015 and 2014 include the accounts of ImmunoGen, Inc., or the Company, and its wholly owned subsidiaries, ImmunoGen Securities Corp., ImmunoGen Europe Limited and Hurricane, LLC. The consolidated financial statements include all of the adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation of the Company’s financial position in accordance with accounting principles generally accepted in the U.S. for interim financial information. The June 30, 2015 condensed consolidated balance sheet data presented for comparative purposes was derived from our audited financial statements but certain information and footnote disclosures normally included in the Company’s annual financial statements have been condensed or omitted. The preparation of interim financial statements requires the use of management’s estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim financial statements and the reported amounts of revenues and expenditures during the reported periods. The results of the interim periods are not necessarily indicative of the results for the entire year. Accordingly, the interim financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended June 30, 2015.

 

Subsequent Events

 

The Company has evaluated all events or transactions that occurred after September 30, 2015 up through the date the Company issued these financial statements. In October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The Company did not have any other material recognizable or unrecognizable subsequent events during this period.

 

Revenue Recognition

 

The Company enters into licensing and development agreements with collaborative partners for the development of monoclonal antibody-based anticancer therapeutics. The terms of these agreements contain multiple deliverables which may include (i) licenses, or options to obtain licenses, to the Company’s antibody-drug conjugate, or ADC, technology, (ii) rights to future technological improvements, (iii) research activities to be performed on behalf of the collaborative partner, (iv) delivery of cytotoxic agents and (v) the manufacture of preclinical or clinical materials for the collaborative partner. Payments to the Company under these agreements may include upfront fees, option fees, exercise fees, payments for research activities, payments for the manufacture of preclinical or clinical materials, payments based upon the achievement of certain milestones and royalties on product sales. The Company follows the provisions of the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 605-25, “Revenue Recognition—Multiple-Element Arrangements,” and ASC Topic 605-28, “Revenue Recognition-Milestone Method,” in accounting for these agreements. In order to account for these agreements, the Company must identify the deliverables included within the agreement and evaluate which deliverables represent separate units of accounting based on if certain criteria are met, including whether the delivered element has stand-alone value to the collaborator. The consideration received is allocated among the separate units of accounting, and the applicable revenue recognition criteria are applied to each of the separate units.

 

At September 30, 2015, the Company had the following two types of agreements with the parties identified below:

 

·                  Development and commercialization licenses, which provide the party with the right to use the Company’s ADC technology and/or certain other intellectual property to develop compounds to a specified antigen target:

 

Amgen (four exclusive single-target licenses(1))

 

Bayer HealthCare (one exclusive single-target license)

 

Biotest (one exclusive single-target license)

 

Lilly (three exclusive single-target licenses)

 


(1) Amgen has sublicensed one of its exclusive single-target licenses to Oxford BioTherapeutics Ltd.

 

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Novartis (five exclusive single-target licenses and one license to two related targets: one target on an exclusive basis and the second target on a non-exclusive basis)

 

Roche, through its Genentech unit (five exclusive single-target licenses)

 

Sanofi (one exclusive single-target license and one exclusive license to multiple individual targets)

 

·                  Research license/option agreement for a defined period of time to secure development and commercialization licenses to use the Company’s ADC technology to develop anticancer compounds to specified targets on established terms (referred to herein as right-to-test agreements):

 

Sanofi

 

CytomX

 

Takeda, through its wholly owned subsidiary, Millennium Pharmaceuticals, Inc.

 

There are no performance, cancellation, termination or refund provisions in any of the arrangements that contain material financial consequences to the Company.

 

Development and Commercialization Licenses

 

The deliverables under a development and commercialization license agreement generally include the license to the Company’s ADC technology with respect to a specified antigen target, and may also include deliverables related to rights to future technological improvements, research activities to be performed on behalf of the collaborative partner and the manufacture of preclinical or clinical materials for the collaborative partner.

 

Generally, development and commercialization licenses contain non-refundable terms for payments and, depending on the terms of the agreement, provide that the Company will (i) at the collaborator’s request, provide research services at negotiated prices which are generally consistent with what other third parties would charge, (ii) at the collaborator’s request, manufacture and provide to it preclinical and clinical materials or deliver cytotoxic agents at negotiated prices which are generally consistent with what other third parties would charge, (iii) earn payments upon the achievement of certain milestones and (iv) earn royalty payments, generally until the later of the last applicable patent expiration or 10 to 12 years after product launch. In the case of Kadcyla, however, the minimum royalty term is 10 years and the maximum royalty term is 12 years on a country by country basis, regardless of patent protection.  Royalty rates may vary over the royalty term depending on the Company’s intellectual property rights and/or the presence of comparable competing products. The Company may provide technical assistance and share any technology improvements with its collaborators during the term of the collaboration agreements. The Company does not directly control when or whether any collaborator will request research or manufacturing services, achieve milestones or become liable for royalty payments. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

In determining the units of accounting, management evaluates whether the license has stand-alone value from the undelivered elements to the collaborative partner based on the consideration of the relevant facts and circumstances for each arrangement. Factors considered in this determination include the research capabilities of the partner and the availability of ADC technology research expertise in the general marketplace. If the Company concludes that the license has stand-alone value and therefore will be accounted for as a separate unit of accounting, the Company then determines the estimated selling prices of the license and all other units of accounting based on market conditions, similar arrangements entered into by third parties, and entity-specific factors such as the terms of the Company’s previous collaborative agreements, recent preclinical and clinical testing results of therapeutic products that use the Company’s ADC technology, the Company’s pricing practices and pricing objectives, the likelihood that technological improvements will be made, and, if made, will be used by the Company’s collaborators and the nature of the research services to be performed on behalf of its collaborators and market rates for similar services.

 

Upfront payments on development and commercialization licenses are deferred if facts and circumstances dictate that the license does not have stand-alone value. Prior to the adoption of Accounting Standards Update (ASU) No. 2009-13, “Revenue Arrangements with Multiple Deliverables” on July 1, 2010, the Company determined that its licenses lacked stand-alone value and were combined with other elements of the arrangement and any amounts associated with the license were deferred and amortized over a certain period, which the Company refers to as the Company’s period of substantial involvement. The determination of the length of the period over which to defer revenue is subject to judgment and estimation and can have an impact on the amount of revenue recognized in a given period. Historically the Company’s involvement with the development of a collaborator’s product candidate has been significant at the early stages of development, and lessens as it progresses into clinical trials. Also, as a drug candidate gets closer

 

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to commencing pivotal testing the Company’s collaborators have sought an alternative site to manufacture their products, as the Company’s facility does not produce pivotal or commercial drug product. Accordingly, the Company generally estimates this period of substantial involvement to begin at the inception of the collaboration agreement and conclude at the end of non-pivotal Phase II testing. The Company believes this period of substantial involvement is, depending on the nature of the license, on average six and one-half years. Quarterly, the Company reassesses its periods of substantial involvement over which the Company amortizes its upfront license fees and makes adjustments as appropriate. In the event a collaborator elects to discontinue development of a specific product candidate under a development and commercialization license, but retains its right to use the Company’s technology to develop an alternative product candidate to the same target or a target substitute, the Company would cease amortization of any remaining portion of the upfront fee until there is substantial preclinical activity on another product candidate and its remaining period of substantial involvement can be estimated. In the event that a development and commercialization license were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination.

 

Subsequent to the adoption of ASU No. 2009-13, the Company determined that its research licenses lack stand-alone value and are considered for aggregation with the other elements of the arrangement and accounted for as one unit of accounting.

 

Upfront payments on development and commercialization licenses may be recognized upon delivery of the license if facts and circumstances dictate that the license has stand-alone value from the undelivered elements, which generally include rights to future technological improvements, research services, delivery of cytotoxic agents and the manufacture of preclinical and clinical materials.

 

The Company recognizes revenue related to research services that represent separate units of accounting as they are performed, as long as there is persuasive evidence of an arrangement, the fee is fixed or determinable, and collection of the related receivable is probable. The Company recognizes revenue related to the rights to future technological improvements over the estimated term of the applicable license.

 

The Company may also provide cytotoxic agents to its collaborators or produce preclinical and clinical materials at negotiated prices which are generally consistent with what other third parties would charge. The Company recognizes revenue on cytotoxic agents and on preclinical and clinical materials when the materials have passed all quality testing required for collaborator acceptance and title and risk of loss have transferred to the collaborator. Arrangement consideration allocated to the manufacture of preclinical and clinical materials in a multiple-deliverable arrangement is below the Company’s full cost, and the Company’s full cost is not expected to ever be below its contract selling prices for its existing collaborations. During the three months ended September 30, 2015 and 2014, the difference between the Company’s full cost to manufacture preclinical and clinical materials on behalf of its collaborators as compared to total amounts received from collaborators for the manufacture of preclinical and clinical materials was $7.0 million and $3.1 million, respectively. The majority of the Company’s costs to produce these preclinical and clinical materials are fixed and then allocated to each batch based on the number of batches produced during the period. Therefore, the Company’s costs to produce these materials are significantly impacted by the number of batches produced during the period. The volume of preclinical and clinical materials the Company produces is directly related to the number of clinical trials the Company and its collaborators are preparing for or currently have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period such trials last. Accordingly, the volume of preclinical and clinical materials produced, and therefore the Company’s per-batch costs to manufacture these preclinical and clinical materials, may vary significantly from period to period.

 

The Company may also produce research material for potential collaborators under material transfer agreements. Additionally, the Company performs research activities, including developing antibody specific conjugation processes, on behalf of its collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The Company records amounts received for research materials produced or services performed as a component of research and development support revenue. The Company also develops conjugation processes for materials for later-stage testing and commercialization for certain collaborators. The Company is compensated at negotiated rates and may receive milestone payments for developing these processes which are recorded as a component of research and development support revenue.

 

The Company’s development and commercialization license agreements have milestone payments which for reporting purposes are aggregated into three categories: (i) development milestones, (ii) regulatory milestones, and (iii) sales milestones. Development milestones are typically payable when a product candidate initiates or advances into different clinical trial phases. Regulatory milestones are typically payable upon submission for marketing approval with the U.S. Food and Drug Administration, or FDA, or other countries’ regulatory authorities or on receipt of actual marketing approvals for the compound or for additional indications. Sales milestones are typically payable when annual sales reach certain levels.

 

At the inception of each agreement that includes milestone payments, the Company evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of

 

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whether (a) the consideration is commensurate with either (1) the entity’s performance to achieve the milestone, or (2) the enhancement of the value of the delivered item(s) as a result of a specific outcome resulting from the entity’s performance to achieve the milestone, (b) the consideration relates solely to past performance and (c) the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. The Company evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment.

 

Non-refundable development and regulatory milestones that are expected to be achieved as a result of the Company’s efforts during the period of substantial involvement are considered substantive and are recognized as revenue upon the achievement of the milestone, assuming all other revenue recognition criteria are met. Milestones that are not considered substantive because the Company does not contribute effort to the achievement of such milestones are generally achieved after the period of substantial involvement and are recognized as revenue upon achievement of the milestone, as there are no undelivered elements remaining and no continuing performance obligations, assuming all other revenue recognition criteria are met.

 

Under the Company’s development and commercialization license agreements, the Company receives royalty payments based upon its licensees’ net sales of covered products. Generally, under these agreements the Company is to receive royalty reports and payments from its licensees approximately one quarter in arrears, that is, generally in the third month of the quarter after the licensee has sold the royalty-bearing product or products. The Company recognizes royalty revenues when it can reliably estimate such amounts and collectability is reasonably assured. As such, the Company generally recognizes royalty revenues in the quarter reported to the Company by its licensees, or one quarter following the quarter in which sales by the Company’s licensees occurred.

 

Right-to-Test Agreements

 

The Company’s right-to-test agreements provide collaborators the right to (a) test the Company’s ADC technology for a defined period of time through a research, or right-to-test, license, (b) take options, for a defined period of time, to specified targets and (c) upon exercise of those options, secure or “take” licenses to develop and commercialize products for the specified targets on established terms. Under these agreements, fees may be due to the Company (i) at the inception of the arrangement (referred to as “upfront” fees or payments), (ii) upon taking an option with respect to a specific target (referred to as option fees or payments earned, if any, when the option is “taken”), (iii) upon the exercise of a previously taken option to acquire a development and commercialization license(s) (referred to as exercise fees or payments earned, if any, when the development and commercialization license is “taken”), or (iv) some combination of all of these fees.

 

The accounting for right-to-test agreements is dependent on the nature of the options granted to the collaborative partner. Options are considered substantive if, at the inception of a right-to-test agreement, the Company is at risk as to whether the collaborative partner will choose to exercise the options to secure development and commercialization licenses. Factors that are considered in evaluating whether options are substantive include the overall objective of the arrangement, the benefit the collaborator might obtain from the agreement without exercising the options, the cost to exercise the options relative to the total upfront consideration, and the additional financial commitments or economic penalties imposed on the collaborator as a result of exercising the options.

 

For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are considered substantive, the Company does not consider the development and commercialization licenses to be a deliverable at the inception of the agreement. For those right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 where the options to secure development and commercialization licenses are considered substantive, the Company has deferred the upfront payments received and recognizes this revenue over the period during which the collaborator could elect to take options for development and commercialization licenses. These periods are specific to each collaboration agreement. If a collaborator takes an option to acquire a development and commercialization license under these agreements, any substantive option fee is deferred and recognized over the life of the option, generally 12 to 18 months. If a collaborator exercises an option and takes a development and commercialization license to a specific target, the Company attributes the exercise fee to the development and commercialization license. Upon exercise of an option to acquire a development and commercialization license, the Company would also attribute any remaining deferred option fee to the development and commercialization license and apply the multiple-element revenue recognition criteria to the development and commercialization license and any other deliverables to determine the appropriate revenue recognition, which will be consistent with the Company’s accounting policy for upfront payments on single-target licenses. In the event a right-to-test agreement were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination. None of the Company’s right-to-test agreements entered into subsequent to the adoption of ASU No. 2009-13 has been determined to contain substantive options.

 

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For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are not considered substantive, the Company considers the development and commercialization licenses to be a deliverable at the inception of the agreement and applies the multiple-element revenue recognition criteria to determine the appropriate revenue recognition. None of the Company’s right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 has been determined to contain non-substantive options.

 

The Company does not directly control when or if any collaborator will exercise its options for development and commercialization licenses. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

Financial Instruments and Concentration of Credit Risk

 

Cash and cash equivalents are primarily maintained with three financial institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and, therefore, bear minimal risk. The Company’s cash equivalents consist of money market funds with underlying investments primarily being U.S. Government issued securities and high quality, short term commercial paper. Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash, cash equivalents and marketable securities. The Company held no marketable securities as of September 30, 2015 and June 30, 2015. The Company’s investment policy, approved by the Board of Directors, limits the amount it may invest in any one type of investment, thereby reducing credit risk concentrations.

 

Cash and Cash Equivalents

 

All highly liquid financial instruments with maturities of three months or less when purchased are considered cash equivalents. As of September 30, 2015 and June 30, 2015, the Company held $247.8 million and $278.1 million, respectively, in cash and money market funds consisting principally of U.S. Government-issued securities and high quality, short-term commercial paper which were classified as cash and cash equivalents.

 

Fair Value of Financial Instruments

 

Fair value is defined under ASC Topic 820, “Fair Value Measurements and Disclosures,” as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date.  Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs.  The standard describes a fair value hierarchy to measure fair value which is based on three levels of inputs, of which the first two are considered observable and the last unobservable, as follows:

 

·                            Level 1 - Quoted prices in active markets for identical assets or liabilities.

 

·                            Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

 

·                            Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

 

As of September 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.  The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of September 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at September 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

240,643

 

$

240,643

 

$

 

$

 

 

As of June 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of June 30, 2015 (in thousands):

 

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Fair Value Measurements at June 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

269,304

 

$

269,304

 

$

 

$

 

 

The fair value of the Company’s cash equivalents is based primarily on quoted prices from active markets.

 

Unbilled Revenue

 

The majority of the Company’s unbilled revenue at September 30, 2015 and June 30, 2015 represents research funding earned prior to those dates based on actual resources utilized under the Company’s agreements with various collaborators.

 

Inventory

 

Inventory costs relate to clinical trial materials being manufactured for sale to the Company’s collaborators. Inventory is stated at the lower of cost or market as determined on a first-in, first-out (FIFO) basis.

 

Inventory at September 30, 2015 and June 30, 2015 is summarized below (in thousands):

 

 

 

September 30,
2015

 

June 30,
2015

 

 

 

 

 

 

 

Raw materials

 

$

76

 

$

279

 

Work in process

 

1,170

 

2,656

 

 

 

 

 

 

 

Total

 

$

1,246

 

$

2,935

 

 

Raw materials inventory consists entirely of DM1 and DM4, proprietary cell-killing agents the Company developed as part of its ADC technology. The Company considers more than a twelve month supply of raw materials that is not supported by firm, fixed orders and/or projections from its collaborators to be excess and establishes a reserve to reduce to zero the value of any such excess raw material inventory with a corresponding charge to research and development expense. In accordance with this policy, the Company recorded no expense related to excess inventory during the three-month period ended September 30, 2015 and $337,000 of expense during the three months ended September 30, 2014.

 

Work in process inventory consists of conjugate manufactured for sale to the Company’s collaborators to be used in preclinical and clinical studies.  All conjugate is made to order at the request of the collaborators and subject to the terms and conditions of respective supply agreements.  As such, no reserve for work in process inventory is required.

 

Computation of Net Loss per Common Share

 

Basic and diluted net loss per share is calculated based upon the weighted average number of common shares outstanding during the period. During periods of income, participating securities are allocated a proportional share of income determined by dividing total weighted average participating securities by the sum of the total weighted average common shares and participating securities (the “two-class method”). Shares of the Company’s restricted stock participate in any dividends declared by the Company and are therefore considered to be participating securities. Participating securities have the effect of diluting both basic and diluted earnings per share during periods of income. During periods of loss, no loss is allocated to participating securities since they have no contractual obligation to share in the losses of the Company. Diluted (loss) income per share is computed after giving consideration to the dilutive effect of stock options and restricted stock that are outstanding during the period, except where such non-participating securities would be anti-dilutive.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Options outstanding to purchase common stock and unvested restricted stock (in thousands)

 

11,494

 

10,564

 

 

 

 

 

 

 

Common stock equivalents under treasury stock method

 

1,296

 

1,147

 

 

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The Company’s common stock equivalents have not been included in any net loss per share calculation because their effect is anti-dilutive due to the Company’s net loss position.

 

Stock-Based Compensation

 

As of September 30, 2015, the Company is authorized to grant future awards under one employee share-based compensation plan, which is the ImmunoGen, Inc. 2006 Employee, Director and Consultant Equity Incentive Plan, or the 2006 Plan. At the annual meeting of shareholders on November 11, 2014, an amendment to the 2006 Plan was approved and an additional 5,500,000 shares were authorized for issuance under this plan.  As amended, the 2006 Plan provides for the issuance of Stock Grants, the grant of Options and the grant of Stock-Based Awards for up to 17,500,000 shares of the Company’s common stock, as well as 1,676,599 shares of common stock which represent awards granted under the previous stock option plan, the ImmunoGen, Inc. Restated Stock Option Plan, or the Former Plan, that were forfeited, expired or were cancelled without delivery of shares of common stock or which resulted in the forfeiture of shares of common stock back to the Company between November 11, 2006 and June 30, 2014. Option awards are granted with an exercise price equal to the market price of the Company’s stock at the date of grant. Options vest at various periods of up to four years and may be exercised within ten years of the date of grant.

 

The stock-based awards are accounted for under ASC Topic 718, “Compensation—Stock Compensation.” Pursuant to Topic 718, the estimated grant date fair value of awards is charged to the statement of operations and comprehensive loss over the requisite service period, which is the vesting period. Such amounts have been reduced by an estimate of forfeitures of all unvested awards. The fair value of each stock option is estimated on the date of grant using the Black-Scholes option-pricing model with the assumptions noted in the following table. As the Company has not paid dividends since inception, nor does it expect to pay any dividends for the foreseeable future, the expected dividend yield assumption is zero. Expected volatility is based exclusively on historical volatility data of the Company’s stock. The expected term of stock options granted is based exclusively on historical data and represents the period of time that stock options granted are expected to be outstanding. The expected term is calculated for and applied to one group of stock options as the Company does not expect substantially different exercise or post-vesting termination behavior among its option recipients. The risk-free rate of the stock options is based on the U.S. Treasury rate in effect at the time of grant for the expected term of the stock options.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Dividend

 

None

 

None

 

Volatility

 

67.07

%

60.44

%

Risk-free interest rate

 

1.89

%

1.88

%

Expected life (years)

 

6.3

 

6.3

 

 

Using the Black-Scholes option-pricing model, the weighted average grant date fair values of options granted during the three months ended September 30, 2015 and 2014 were $10.31 and $6.27 per share, respectively.

 

Stock compensation expense related to stock options and restricted stock awards granted under the 2006 Plan was $5.7 million and $5.3 million during the three months ended September 30, 2015 and 2014, respectively. As of September 30, 2015, the estimated fair value of unvested employee awards was $35 million, net of estimated forfeitures. The weighted-average remaining vesting period for these awards is approximately two and a half years.

 

During the three months ended September 30, 2015, holders of options issued under the Company’s equity plans exercised their rights to acquire an aggregate of approximately 402,000 shares of common stock at prices ranging from $3.19 to $17.00 per share.  The total proceeds to the Company from these option exercises were approximately $4.5 million.

 

Segment Information

 

During the three months ended September 30, 2015, the Company continued to operate in one operating segment which is the business of discovery of monoclonal antibody-based anticancer therapeutics.

 

The percentages of revenues recognized from significant customers of the Company in the three months ended September 30, 2015 and 2014 are included in the following table:

 

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Three Months Ended
September 30,

 

Collaborative Partner:

 

2015

 

2014

 

Biotest

 

16

%

11

%

Lilly

 

35

%

3

%

Sanofi

 

 

45

%

Roche

 

38

%

32

%

 

There were no other customers of the Company with significant revenues in the three months ended September 30, 2015 and 2014.

 

Recent Accounting Pronouncements

 

In May 2014, the FASB issued Accounting Standards Update 2014-9, Revenue from Contracts with Customers (Topic 606) (“ASU 2014-09”), to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required the Company to adopt beginning in its first quarter of fiscal 2018. In July 2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.  Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. The Company is currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on its consolidated financial statements and related disclosures.

 

In August 2014, the FASB issued Accounting Standards Update 2014-15, Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern. This new standard gives a company’s management the final responsibilities to decide whether there’s substantial doubt about the company’s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company’s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

In April 2015, the FASB issued Accounting Standards Update 2015-03, Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs. To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.  The recognition and measurement guidance for debt issuance costs are not affected by this update.  This guidance is effective for annual reporting beginning after December 15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2016. The Company’s consolidated balance sheet as of September 30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.

 

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In July 2015, the FASB issued Accounting Standards Update 2015-11, Simplifying the Measurement of Inventory (Topic 330). To simplify the principles for subsequent measurement of inventory, this new standard requires inventory measured using any method other than LIFO or the retail method shall be measured at the lower of cost and net realizable value, rather than lower of cost or market. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, and calls for prospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

B.            Collaborative Agreements

 

Lilly

 

Eli Lilly and Company (Lilly) had the right to take three exclusive development and commercialization licenses under a right-to-test agreement established in December 2011, and took these licenses prior to the expiration of the agreement in December 2014. The Company received a $20 million upfront payment in connection with the execution of the right-to-test agreement in 2011.  Under the terms of this right-to-test agreement, the first license had no associated exercise fee, and the second and third licenses each had a $2 million exercise fee. The first development and commercialization license was taken in August 2013 and the agreement was amended in December 2013 to provide Lilly with an extension provision and retrospectively include a $2 million exercise fee for the first license in lieu of the fee due for either the second or third license. The second and third licenses were taken in December 2014, with one including the $2 million exercise fee and the other not. Under the two licenses with the $2 million exercise fee, the Company is entitled to receive up to a total of $199 million in milestone payments, plus royalties on the commercial sales of any resulting products.  Under the license taken in December 2014 without the exercise fee, the Company is entitled to receive up to a total of $200.5 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$29 million for the two development and commercialization licenses with the $2 million exercise fee, and $30.5 million for the one development and commercialization license with no exercise fee; regulatory milestones—$70 million in all cases; and sales milestones—$100 million in all cases.

 

In September 2015, Lilly initiated Phase I, first-in-human clinical testing of its ADC product candidate, LY3076226, triggering a $5 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September 30, 2015.  The next payment the Company could receive would be either a $9 million milestone for commencement of a Phase II clinical trial under this license or a $5 million development milestone payment with the commencement of a Phase I clinical trial under either of its other two licenses.  At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s expected involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive. The Company also is entitled to receive payments for delivery of cytotoxic agents to Lilly and research and development activities performed on behalf of Lilly. Lilly is responsible for the manufacturing, product development and marketing of any products resulting from this collaboration.

 

Amgen

 

Under a now-expired right-to-test agreement, in September 2009, November 2009 and December 2012, Amgen took three exclusive development and commercialization licenses, for which the Company received an exercise fee of $1 million for each license taken. In May 2013, Amgen took one non-exclusive development and commercialization license, for which the Company received an exercise fee of $500,000. In October 2013, the non-exclusive license was amended and converted to an exclusive license, for which Amgen paid an additional $500,000 fee to the Company. Amgen has sublicensed its rights under this license to Oxford BioTherapeutics Ltd. For each development and commercialization license taken, the Company is entitled to receive up to a total of $34 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones per license are categorized as follows: development milestones—$9 million; regulatory milestones—$20 million; and sales milestones—$5 million. Amgen (or its sublicensee(s)) is responsible for the manufacturing, product development and marketing of any products resulting from these development and commercialization licenses.

 

In September 2015, the IND application for its third ADC product candidate became effective, triggering a $1 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September 30, 2015. In November 2011, the IND applications to the FDA for its product candidates AMG 595 and AMG 172 became effective, which triggered two $1 million milestone payments to the Company. The next potential milestone the Company will be entitled to receive under these three licenses will be a development milestone for the first dosing of a patient in a Phase II clinical trial, which will result in a $3 million payment being due. The next potential milestone the Company will be entitled to receive under the May 2013 license will be a $1 million development milestone for an IND becoming effective. At the time of execution of each of these development and commercialization licenses, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s past involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive.

 

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Sanofi

 

In July 2003, the Company entered into a broad collaboration agreement with Sanofi (formerly Aventis) to discover, develop and commercialize antibody-based products. The collaboration agreement provides Sanofi with worldwide development and commercialization rights to new antibody-based products directed to targets that are included in the collaboration, including the exclusive right to use the Company’s maytansinoid ADC technology in the creation of products developed to these targets. The product candidates (targets) as of September 30, 2015 in the collaboration include SAR650984 (CD38), SAR566658 (CA6), SAR408701 (CEACAM5) and one earlier-stage compound that has yet to be disclosed.

 

We are entitled to receive milestone payments potentially totaling $21.5 million, per target, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$7.5 million; and regulatory milestones—$14 million. Through September 30, 2015, the Company has received and recognized an aggregate of $20.5 million in milestone payments for compounds covered under this agreement now or in the past, including a $3 million development milestone related to initiation of a Phase IIb clinical trial (as defined in the agreement) for SAR650984 and a $1 million development milestone related to initiation of a Phase I clinical trial for SAR408701 which are included in license and milestone fee revenue for the three months ended September 30, 2014.

 

In December 2006, we entered into a right-to-test agreement with Sanofi. The agreement provides Sanofi with the right to (a) test the Company’s maytansinoid ADC technology with Sanofi’s antibodies to targets under a right-to-test, or research, license, (b) take exclusive options, with certain restrictions, to specified targets for specified option periods and (c) upon exercise of those options, take exclusive licenses to use the Company’s maytansinoid ADC technology to develop and commercialize products directed to the specified targets on terms agreed upon at the inception of the right-to-test agreement. Sanofi no longer has the right to take additional options under the agreement, although multiple outstanding options remain in effect for the remainder of their respective option periods. For each development and commercialization license taken, the Company is entitled to receive an exercise fee of $2 million and up to a total of $30 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$10 million; and regulatory milestones—$20 million.

 

In December 2013, Sanofi took its first exclusive development and commercialization license under the right-to-test agreement, for which the Company received an exercise fee of $2 million and was recognizing this amount as revenue ratably over the Company’s estimated period of its substantial involvement. The Company had previously estimated this development period would conclude at the end of non-pivotal Phase II testing.  During the first quarter of fiscal 2015, the Company determined it will not be substantially involved in the development and commercialization of the product based on Sanofi’s current plans to develop and manufacture the product without the Company’s assistance. As a result of this determination, we recognized the balance of the upfront exercise fee during the prior period.  This change in estimate resulted in an increase to license and milestone fees of $1.7 million for the three months ended September 30, 2014 compared to amounts that would have been recognized pursuant to the Company’s previous estimate.

 

Pursuant to the license agreement noted above, in October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The next milestone payment the Company could receive would be a $4 million development milestone for commencement of a Phase IIb clinical trial (as defined in the agreement) under this license. At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s past involvement in the research and manufacturing of Sanofi’s product candidates, these milestones were deemed substantive.

 

For additional information related to these agreements, as well as the Company’s other significant collaborative agreements, please read Note C, Agreements to our consolidated financial statements included within the Company’s 2015 Form 10-K.

 

C.    Liability Related to Sale of Future Royalties

 

In April 2015, Immunity Royalty Holdings, L.P. (IRH) purchased the right to receive 100% of the royalty payments on commercial sales of Kadcyla arising under the Company’s development and commercialization license with Genentech, until IRH has received aggregate royalties equal to $235 million or $260 million, depending on when the aggregate royalties received by IRH reach a specified milestone.  Once the applicable threshold is met, if ever, the Company will thereafter receive 85% and IRH will receive 15% of the Kadcyla royalties for the remaining royalty term.  At consummation of the transaction in April 2015, the Company received cash proceeds of $200 million.  As part of this sale, the Company incurred $5.9 million of transaction costs, which are presented in the accompanying consolidated balance sheet as deferred financing costs and will be amortized to interest expense over the estimated life of the royalty purchase agreement.  Although the Company sold its rights to receive royalties from the sales of Kadcyla, as a result of its ongoing involvement in the cash flows related to these royalties, the Company will continue to account for these royalties as revenue and recorded the $200 million in proceeds from this transaction as a liability related to sale of future

 

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royalties (Royalty Obligation) that will be amortized using the interest method over the estimated life of the royalty purchase agreement.

 

The following table shows the activity within the liability account during the three-month period ended September 30, 2015 (in thousands):

 

 

 

Period from
June 30, 2015 to
September 30,
2015

 

Liability related to sale of future royalties — beginning balance

 

$

199,662

 

Non-cash Kadcyla royalty revenue

 

(5,684

)

Non-cash interest expense recognized

 

4,851

 

 

 

 

 

Liability related to sale of future royalties — ending balance

 

$

198,829

 

 

As royalties are remitted to IRH, the balance of the Royalty Obligation will be effectively repaid over the life of the agreement.  In order to determine the amortization of the Royalty Obligation, the Company is required to estimate the total amount of future royalty payments to be received and remitted to IRH as noted above over the life of the agreement. The sum of these amounts less the $200 million proceeds the Company received will be recorded as interest expense over the life of the Royalty Obligation. Since inception, the Company’s estimate of this total interest expense resulted in an effective annual interest rate of 9.8%. The Company periodically assesses the estimated royalty payments to IRH and to the extent such payments are greater or less than its initial estimates, or the timing of such payments is materially different than its original estimates, the Company will prospectively adjust the amortization of the Royalty Obligation. There are a number of factors that could materially affect the amount and timing of royalty payments from Genentech, most of which are not within the Company’s control. Such factors include, but are not limited to, changing standards of care, the introduction of competing products, manufacturing or other delays, biosimilar competition, patent protection, adverse events that result in governmental health authority imposed restrictions on the use of the drug products, significant changes in foreign exchange rates as the royalties remitted to IRH are made in U.S. dollars (USD) while significant portions of the underlying sales of Kadcyla are made in currencies other than USD, and other events or circumstances that could result in reduced royalty payments from Kadcyla, all of which would result in a reduction of non-cash royalty revenues and the non-cash interest expense over the life of the Royalty Obligation. Conversely, if sales of Kadcyla are more than expected, the non-cash royalty revenues and the non-cash interest expense recorded by the Company would be greater over the term of the Royalty Obligation.

 

In addition, the royalty purchase agreement grants IRH the right to receive certain reports and other information relating to the royalties and contains other representations and warranties, covenants and indemnification obligations that are customary for a transaction of this nature.

 

D.     Capital Stock

 

2001 Non-Employee Director Stock Plan

 

During the three months ended September 30, 2015, the Company recorded approximately ($30,000) in expense reduction, respectively, related to stock units outstanding under the Company’s 2001 Non-Employee Director Stock Plan, or the 2001 Plan, compared to ($8,000) in expense reduction recorded during the three months ended September 30, 2014. The value of the stock units are classified as a liability and adjusted to market value at each reporting period as the redemption amount of stock units for this plan will be paid in cash.  No stock units have been issued under the 2001 Plan subsequent to June 30, 2004.

 

Compensation Policy for Non-Employee Directors

 

On November 12, 2013, the Board amended the Compensation Policy for Non-Employee Directors to make certain changes to the compensation of its non-employee directors, including an increase in the fees paid in cash to the non-employee directors. Under the terms of the amended policy, the redemption amount of deferred share units issued will continue to be paid in shares of common stock of the Company on the date a director ceases to be a member of the Board. Annual retainers vest quarterly over approximately one year from the date of grant, contingent upon the individual remaining a director of ImmunoGen as of each vesting date.  The number of deferred share units awarded is now fixed per the plan on the date of the award and is no longer based on the market price of the Company’s common stock on the date of the award. All unvested deferred stock awards will automatically vest immediately prior to the occurrence of a change of control.

 

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In addition to the deferred share units, the Non-Employee Directors are also entitled to receive a fixed number of stock options determined using the Black-Scholes option pricing model measured on the date of grant, which would be the date of the annual meeting of shareholders.  These options vest quarterly over approximately one year from the date of grant.  Any new directors will receive a pro-rated award, depending on their date of election to the Board.  The directors received a total of 80,000 stock options in each fiscal year 2015 and 2014, and the related compensation expense for the three months ended September 30, 2015 and 2014 is included in the amounts discussed in the “Stock-Based Compensation” section of footnote A above.

 

During the three months ended September 30, 2015, the Company recorded approximately $82,000 in compensation expense, respectively, related to deferred share units issued and outstanding under the Company’s Compensation Policy for Non-Employee Directors, compared to $118,000 in compensation expense recorded during the three months ended September 30, 2014.

 

E.     Commitments and Contingencies

 

Leases

 

Effective July 27, 2007, the Company entered into a lease agreement with Intercontinental Fund III for the rental of approximately 89,000 square feet of laboratory and office space at 830 Winter Street, Waltham, MA through March 2020. The Company uses this space for its corporate headquarters and other operations. In December 2013, the Company modified its lease agreement at 830 Winter Street, Waltham, MA to include approximately 19,000 square feet of additional office space through 2020, concurrent with the remainder of the original lease term. As part of the lease amendment, the Company received a construction allowance of approximately $746,000 to build out office space to the Company’s specifications. The Company obtained physical control of the additional space to begin construction in January 2014. In April, 2014, the Company again modified its lease agreement at this site to extend the lease to 2026. The Company may extend the lease for two additional terms of five years. As part of this lease amendment, the Company received a construction allowance of approximately $1.1 million to build out office space to the Company’s specifications. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.

 

The Company also leases manufacturing and office space at 333 Providence Highway, Norwood, MA under an agreement through 2018 with an option to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.

 

Effective April 2013, the Company entered into a lease agreement with River Ridge Limited Partnership for the rental of 7,507 square feet of additional office space at 100 River Ridge Drive, Norwood, MA. The initial term of the lease is for five years and two months commencing in July 2013 with an option for the Company to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount. The Company entered into a sublease in December 2014 for this space, effective January 2015 through July 2018.

 

The minimum rental commitments for the Company’s facilities, including real estate taxes and other expenses, for the next five fiscal years and thereafter under the non-cancelable operating lease agreements discussed above are as follows (in thousands):

 

2016 (nine months remaining)

 

$

5,519

 

2017

 

7,147

 

2018

 

7,253

 

2019

 

6,441

 

2020

 

6,423

 

Thereafter

 

38,857

 

Total minimum lease payments

 

$

71,640

 

Total minimum rental payments from sublease

 

(340

)

Total minimum lease payments, net

 

$

71,300

 

 

There are no obligations under capital leases as of September 30, 2015, as all of the capital leases were single payment obligations which have all been made.

 

Collaborations

 

The Company is contractually obligated to make potential future success-based development, regulatory or sales milestone payments in conjunction with certain collaborative agreements. These payments are contingent upon the occurrence of certain future

 

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events and, given the nature of these events, it is unclear when, if ever, the Company may be required to pay such amounts. Further, the timing of any future payment is not reasonably estimable. As of September 30, 2015, the maximum amount that may be payable in the future under the Company’s current collaborative agreements is $162 million, $1.4 million of which is reimbursable by a third party under a separate agreement.

 

ITEM 2.  Management’s Discussion and Analysis of Financial Condition and Results of Operations

 

OVERVIEW

 

Since our inception, we have been principally engaged in the development of novel, antibody-drug conjugates, or ADCs, for the treatment of cancer using our expertise in cancer biology, monoclonal antibodies, highly potent cytotoxic, or cell-killing, agents, and the design of linkers that enable these agents to remain stably attached to the antibodies while in the blood stream and released in their fully active form after delivery to a cancer cell. An anticancer compound made using our ADC technology consists of a monoclonal antibody that binds specifically to an antigen target found on the surface of cancer cells with one of our proprietary cell-killing agents attached to the antibody using one of our engineered linkers. Its antibody component enables an ADC compound to bind specifically to cancer cells that express its target antigen, the highly potent cytotoxic agent serves to kill the cancer cell, and the engineered linker controls the release and activation of the cytotoxic agent inside the cancer cell. With some ADC compounds, the antibody component also has anticancer activity of its own. Our ADC technology is designed to enable the creation of highly effective, well-tolerated anticancer products. All of the ADC compounds currently in clinical testing contain either DM1 or DM4 as the cytotoxic agent. Both DM1 and DM4, collectively DMx, are our proprietary derivatives of a cytotoxic agent called maytansine. We also have developed agents we call IGNs, one of which, DGN462, is used in our preclinical compound IMGN779.

 

We use our proprietary ADC technology in conjunction with our in-house antibody expertise to develop our own anticancer product candidates. We also enter into agreements that enable companies to use our ADC technology to develop and commercialize product candidates to specified targets. Under the terms of our agreements, we are generally entitled to upfront fees, milestone payments, and royalties on any commercial product sales. In addition, under certain agreements we are compensated for research and development activities performed at our collaborative partner’s request at negotiated prices which are generally consistent with what other third parties would charge. We are compensated to manufacture preclinical and clinical materials and deliver cytotoxic agent material at negotiated prices which are generally consistent with what other third parties would charge. Currently, our partners include Amgen, Bayer HealthCare, Biotest, Lilly, Novartis, Roche, Sanofi and Takeda. We also have a research agreement with CytomX Therapeutics that allows each company to develop probody-drug conjugates against a specified number of cancer targets using CytomX’s Probody antibody masking technology with our payload agents and engineered linkers. We expect that substantially all of our revenue for the foreseeable future will result from payments under our collaborative arrangements. Details for all of our significant agreements can be found in our 2015 Annual Report on Form 10-K

 

Roche—In May 2000, we granted Genentech, now a unit of Roche, an exclusive license to use our maytansinoid ADC technology with antibodies, such as trastuzumab, or other proteins that target HER2. Pursuant to this agreement, Roche developed and received marketing approval for its HER2-targeting ADC compound, Kadcyla, in the U.S., Europe, Japan and numerous other countries. We receive royalty reports and payments related to sales of Kadcyla from Roche one quarter in arrears. In accordance with our revenue recognition policy, $5.7 million of non-cash royalties on net sales of Kadcyla for the three-month period ended June 30, 2015 were recorded and included in revenue for the three months ended September 30, 2015 and $4.2 million of royalties on net sales of Kadcyla for the three-month period ended June 30, 2014 were included in royalty revenue for the three months ended September 30, 2014. In April 2015, we consummated a royalty purchase transaction — see Liquidity and Capital Resources below for further details.

 

Amgen— Under a now-expired right-to-test agreement, in December 2012, Amgen took an exclusive development and commercialization license, for which the Company received an exercise fee of $1 million. The Company is also entitled to receive up to a total of $34 million in milestone payments, plus royalties on the commercial sales of any resulting products from this license. The total milestones are categorized as follows: development milestones—$9 million; regulatory milestones—$20 million; and sales milestones—$5 million. In September 2015, the IND application for its third ADC product candidate under this license became effective, triggering a $1 million milestone payment to us which is included in license and milestone fee revenue for the three months ended September 30, 2015.

 

Sanofi— In July 2003, we entered into a broad collaboration agreement with Sanofi (formerly Aventis) to discover, develop and commercialize antibody-based products. The collaboration agreement provides Sanofi with worldwide development and commercialization rights to new antibody-based products directed to targets that are included in the collaboration, including the exclusive right to use our maytansinoid ADC technology in the creation of products developed to these targets. The product candidates (targets) as of September 30, 2015 in the collaboration include SAR650984 (CD38), SAR566658 (CA6), SAR408701 (CEACAM5) and one earlier-stage compound that has yet to be disclosed.

 

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We are entitled to receive milestone payments potentially totaling $21.5 million, per target, payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$7.5 million; and regulatory milestones—$14 million. Through September 30, 2015, we have received and recognized an aggregate of $20.5 million in milestone payments for compounds covered under this agreement now or in the past, including a $3 million development milestone related to initiation of a Phase IIb clinical trial (as defined in the agreement) for SAR650984 and a $1 million development milestone related to initiation of a Phase I clinical trial for SAR408701 which are included in license and milestone fee revenue for the three months ended September 30, 2014.

 

In December 2006, we entered into a right-to-test agreement with Sanofi. The agreement provides Sanofi with the right to (a) test our maytansinoid ADC technology with Sanofi’s antibodies to targets under a right-to-test, or research, license, (b) take exclusive options, with certain restrictions, to specified targets for specified option periods and (c) upon exercise of those options, take exclusive licenses to use our maytansinoid ADC technology to develop and commercialize products directed to the specified targets on terms agreed upon at the inception of the right-to-test agreement. Sanofi no longer has the right to take additional options under the agreement, although multiple outstanding options remain in effect for the remainder of their respective option periods. For each development and commercialization license taken, we are entitled to receive an exercise fee of $2 million and up to a total of $30 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$10 million; and regulatory milestones—$20 million.

 

In December 2013, Sanofi took its first exclusive development and commercialization license under the right-to-test agreement, for which we received an exercise fee of $2 million and was recognizing this amount as revenue ratably over our estimated period of its substantial involvement. We had previously estimated this development period would conclude at the end of non-pivotal Phase II testing.  During the first quarter of fiscal 2015, we determined we will not be substantially involved in the development and commercialization of the product based on Sanofi’s current plans to develop and manufacture the product without our assistance. As a result of this determination, we recognized the balance of the upfront exercise fee during the prior period.  This change in estimate resulted in an increase to license and milestone fees of $1.7 million for the three months ended September 30, 2014 compared to amounts that would have been recognized pursuant to our previous estimate.

 

Pursuant to the license agreement noted above, in October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to us.

 

Lilly— Under a now-expired right-to-test agreement executed in December 2011, Lilly has taken three exclusive development and commercialization licenses. We received a $20 million upfront payment in connection with the execution of the right-to-test agreement, and for the first development and commercialization license taken in August 2013 and amended in December 2013, we received an exercise fee in the amount of $2 million and are entitled to receive up to a total of $199 million in milestone payments, plus royalties on the commercial sales of any resulting products. The second and third exclusive licenses were taken in December 2014, one of which we received an exercise fee in the amount of $2 million and are entitled to receive up to a total of $199 million in milestone payments, plus royalties on the commercial sales of any resulting products.  For the third license taken in December 2014, for which we did not receive an exercise fee, we are entitled to receive up to a total of $200.5 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$29 million for the two development and commercialization licenses with the $2 million exercise fee, and $30.5 million for the one development and commercialization license with no exercise fee; regulatory milestones—$70 million in all cases; and sales milestones—$100 million in all cases. In September 2015, Lilly began Phase I evaluation of one of their potential products which triggered a $5 million milestone payment to us which is included in license and milestone fee revenue for the three months ended September 30, 2015.

 

To date, we have not generated revenues from commercial sales of internal products and we expect to incur significant operating losses for the foreseeable future. As of September 30, 2015, we had approximately $247.8 million in cash and cash equivalents compared to $278.1 million in cash and cash equivalents as of June 30, 2015.

 

We anticipate that future cash expenditures will be partially offset by collaboration-derived proceeds, including milestone payments and upfront fees. Accordingly, period-to-period operational results may fluctuate dramatically based upon the timing of receipt of the proceeds. We believe that our established collaborative agreements, while subject to specified milestone achievements, will provide funding to assist us in meeting obligations under our collaborative agreements while also assisting in providing funding for the development of internal product candidates and technologies. However, we can give no assurances that such collaborative agreement funding will, in fact, be realized in the time frames we expect, or at all. Should we or our partners not meet some or all of the terms and conditions of our various collaboration agreements, we may be required to secure alternative financing arrangements, find additional partners and/or defer or limit some or all of our research, development and/or clinical projects. However, we cannot provide assurance that any such opportunities presented by additional partners or alternative financing arrangements will be entirely available to us, if at all.

 

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Critical Accounting Policies

 

We prepare our consolidated financial statements in accordance with accounting principles generally accepted in the U.S. The preparation of these financial statements requires us to make estimates and judgments that affect the reported amounts of assets, liabilities, revenues and expenses and related disclosure of contingent assets and liabilities. On an on-going basis, we evaluate our estimates, including those related to our collaborative agreements, clinical trial accruals, inventory and stock-based compensation. We base our estimates on historical experience and various other assumptions that we believe to be reasonable under the circumstances. Actual results may differ from these estimates.

 

There were no significant changes to our critical accounting policies from those disclosed in our Annual Report on Form 10-K for the fiscal year ended June 30, 2015.

 

RESULTS OF OPERATIONS

 

Comparison of Three Months ended September 30, 2015 and 2014

 

Revenues

 

Our total revenues for the three months ended September 30, 2015 and 2014 were $14.9 million and $13.2 million, respectively. The $1.7 million increase in revenues in the three months ended September 30, 2015 from the same period in the prior year is attributable to an increase in royalty revenue and clinical materials revenue, partially offset by a decrease in license and milestone fees, all of which are discussed below.

 

Revenues from license and milestone fees for the three months ended September 30, 2015 decreased $164,000 to $6.1 million from $6.2 million in the same period ended September 30, 2014. Included in license and milestone fees for the three months ended September 30, 2015 is a $5 million development milestone achieved under a license agreement with Lilly and a $1 million development milestone achieved under a license agreement with Amgen.  The amount of license and milestone fees we earn is directly related to the number of our collaborators, the collaborators’ advancement of the product candidates, and the overall success in the clinical trials of the product candidates. As such, the amount of license and milestone fees may vary significantly from quarter to quarter and year to year.  Total revenue from license and milestone fees recognized from each of our collaborative partners in the three-month periods ended September 30, 2015 and 2014 is included in the following table (in thousands):

 

 

 

Three Months Ended September 30,

 

License and Milestone Fees

 

2015

 

2014

 

Collaborative Partner:

 

 

 

 

 

Amgen

 

$

1,004

 

$

4

 

Biotest

 

6

 

6

 

Janssen

 

 

241

 

Lilly

 

5,006

 

6

 

Novartis

 

45

 

45

 

Sanofi

 

9

 

5,932

 

Total

 

$

6,070

 

$

6,234

 

 

Deferred revenue of $41.7 million as of September 30, 2015 primarily represents consideration received from our collaborators pursuant to our license agreements, which we have yet to earn pursuant to our revenue recognition policy. Included within this amount is a $20 million upfront payment received from Takeda during the prior year and $13 million of non-cash consideration recorded in connection with our arrangement with CytomX during fiscal 2014.

 

Kadcyla is an ADC marketed product resulting from one of our development and commercialization licenses with Roche, through its Genentech unit. We receive royalty reports and payments related to sales of Kadcyla from Roche one quarter in arrears. In accordance with our revenue recognition policy, $5.7 million of non-cash royalties on net sales of Kadcyla for the three-month period ended June 30, 2015 were recorded and included in revenue for the three months ended September 30, 2015 and $4.2 million of

 

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royalties on net sales of Kadcyla for the three-month period ended June 30, 2014 is included in revenue for the three months ended September 30, 2014. We expect non-cash royalty revenue to increase in future periods as the underlying net sales of Kadcyla increase.  In April 2015, we consummated a royalty purchase transaction — see Liquidity and Capital Resources below for further details.

 

Research and development support revenue was $772,000 for the three months ended September 30, 2015 compared with $776,000 for the three months ended September 30, 2014. These amounts primarily represent research funding earned based on actual resources utilized under our agreements with our collaborators shown in the table below. Also included in research and development support revenue are fees for developing antibody-specific conjugation processes on behalf of our collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The amount of research and development support revenue we earn is directly related to the number of our collaborators and potential collaborators, the stage of development of our collaborators’ product candidates and the resources our collaborators allocate to the development effort. As such, the amount of research and development support revenue may vary widely from quarter to quarter and year to year. Total revenue recognized from research and development support from each of our collaborative partners in the three-month periods ended September 30, 2015 and 2014 is included in the following table (in thousands):

 

 

 

Three Months Ended September 30,

 

Research and Development Support

 

2015

 

2014

 

Collaborative Partner:

 

 

 

 

 

Amgen

 

$

30

 

$

19

 

Biotest

 

151

 

110

 

Lilly

 

155

 

409

 

Novartis

 

31

 

197

 

Takeda

 

384

 

 

Other

 

21

 

41

 

Total

 

$

772

 

$

776

 

 

Clinical materials revenue was $2.3 million for the three months ended September 30, 2015 compared with $2.0 million for the three months ended September 30, 2014. We are compensated at negotiated prices which are generally consistent with what other third-parties would charge. The amount of clinical materials revenue we earn, and the related cost of clinical materials charged to research and development expense, is directly related to the number of clinical trials our collaborators who use us to manufacture clinical materials are preparing or have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period, if any, during which patients in the trial receive clinical benefit from the clinical materials, and the demand our collaborators have for clinical-grade material for process development and analytical purposes. As such, the amount of clinical materials revenue and the related cost of clinical materials charged to research and development expense may vary significantly from quarter to quarter and year to year.

 

Research and Development Expenses

 

Our research and development expenses relate to (i) research to evaluate new targets and to develop and evaluate new antibodies, linkers and cytotoxic agents, (ii) preclinical testing of our own and, in certain instances, our collaborators’ product candidates, and the cost of our own clinical trials, (iii) development related to clinical and commercial manufacturing processes and (iv) manufacturing operations which also includes raw materials.

 

Research and development expense for the three months ended September 30, 2015 increased $7.1 million to $35.1 million from $28.0 million for the three months ended September 30, 2014. A more detailed discussion of research and development expense in the period follows.

 

We are unable to accurately estimate which potential product candidates, if any, will eventually move into our internal preclinical research program. We are unable to reliably estimate the costs to develop these products as a result of the uncertainties related to discovery research efforts as well as preclinical and clinical testing. Our decision to move a product candidate into the clinical development phase is predicated upon the results of preclinical tests. We cannot accurately predict which, if any, of the discovery stage product candidates will advance from preclinical testing and move into our internal clinical development program. The clinical trial and regulatory approval processes for our product candidates that have advanced or that we intend to advance to clinical testing are lengthy, expensive and uncertain in both timing and outcome. As a result, the pace and timing of the clinical development of our product candidates is highly uncertain and may not ever result in approved products. Completion dates and development costs will vary significantly for each product candidate and are difficult to predict. A variety of factors, many of which are outside our control, could cause or contribute to the prevention or delay of the successful completion of our clinical trials, or delay or prevent our obtaining necessary regulatory approvals. The costs to take a product through clinical trials are dependent upon, among other factors, the clinical indications, the timing, size and design of each clinical trial, the number of patients enrolled in each trial, and the speed at which patients are enrolled and treated. Product candidates may be found to be ineffective or to cause unacceptable side

 

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effects during clinical trials, may take longer to progress through clinical trials than anticipated, may fail to receive necessary regulatory approvals or may prove impractical to manufacture in commercial quantities at reasonable cost or with acceptable quality.

 

The lengthy process of securing FDA approvals for new drugs requires the expenditure of substantial resources. Any failure by us to obtain, or any delay in obtaining, regulatory approvals, would materially adversely affect our product development efforts and our business overall. Accordingly, we cannot currently estimate, with any degree of certainty, the amount of time or money that we will be required to expend in the future on our product candidates prior to their regulatory approval, if such approval is ever granted. As a result of these uncertainties surrounding the timing and outcome of our clinical trials, we are currently unable to estimate when, if ever, our product candidates that have advanced into clinical testing will generate revenues and cash flows.

 

We do not track our research and development costs by project. Since we use our research and development resources across multiple research and development projects, we manage our research and development expenses within each of the categories listed in the following table and described in more detail below (in thousands):

 

 

 

Three Months Ended September 30,

 

Research and Development Expense

 

2015

 

2014

 

Research

 

$

5,940

 

$

4,988

 

Preclinical and Clinical Testing

 

15,498

 

10,192

 

Process and Product Development

 

2,693

 

2,254

 

Manufacturing Operations

 

11,001

 

10,584

 

Total Research and Development Expense

 

$

35,132

 

$

28,018

 

 

Research:   Research includes expenses primarily associated with activities to identify and evaluate new targets and to develop and evaluate new antibodies, linkers and cytotoxic agents for our products and in support of our collaborators. Such expenses primarily include personnel, contract services, research licensing fees, facilities and lab supplies. Research expenses for the three months ended September 30, 2015 increased $952,000 thousand compared to the three months ended September 30, 2014. This increase is principally due to an increase in salaries and related expenses driven primarily by increases in personnel. We expect research expenses for fiscal 2016 to be higher than fiscal 2015 due to increases in personnel.

 

Preclinical and Clinical Testing: Preclinical and clinical testing includes expenses related to preclinical testing of our own and, in certain instances, our collaborators’ product candidates, regulatory activities, and the cost of our own clinical trials. Such expenses include personnel, patient enrollment at our clinical testing sites, consultant fees, contract services, and facility expenses. Preclinical and clinical testing expenses for the three months ended September 30, 2015 increased $5.3 million to $15.5 million compared to $10.2 million for the three months ended September 30, 2014. This increase is primarily the result of an increase in contract service expense and clinical trial expense driven primarily by increased activities related to mirvetuximab ravtansine.  We expect preclinical and clinical testing expenses for fiscal 2016 to be significantly higher than fiscal 2015 driven primarily by increased activities to advance our wholly owned product candidates, mirvetuximab ravtansine and IMGN529, to Phase II clinical testing, as well as initiate Phase I clinical testing of IMGN779.

 

Process and Product Development:  Process and product development expenses include costs for development of clinical and commercial manufacturing processes for our own and collaborator compounds. Such expenses include the costs of personnel, contract services and facility expenses. For the three months ended September 30, 2015, total development expenses increased $439,000 compared to the three months ended September 30, 2014. We expect process and product development expenses for fiscal 2016 to be significantly higher than fiscal 2015 due to increases in personnel to support internal and partner efforts.

 

Manufacturing Operations: Manufacturing operations expense includes costs to manufacture preclinical and clinical materials for our own and our collaborator’s product candidates, and quality control and quality assurance activities and costs to support the operation and maintenance of our conjugate manufacturing facility. Such expenses include personnel, raw materials for our and our collaborators’ preclinical studies and clinical trials, development costs with contract manufacturing organizations, manufacturing supplies, and facilities expense. For the three months ended September 30, 2015, manufacturing operations expense increased $417,000 to $11.0 million compared to $10.6 million in the same period last year. The increase in the three months ended September 30, 2015 as compared to the three months ended September 30, 2014 is primarily the result of a decrease in costs capitalized into inventory due to a lesser number of manufactured batches of conjugated materials on behalf of our collaborators.  We expect manufacturing operations expense for fiscal 2016 to be higher than fiscal 2015 due primarily to increased activities to advance our wholly owned product candidates.

 

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General and Administrative Expenses

 

General and administrative expenses for the three months ended September 30, 2015 increased $1.2 million compared to the same period last year. This increase is primarily due to inflationary increases in salaries and related expenses and additional personnel. We expect general and administrative expenses for fiscal 2016 to be higher than fiscal 2015 due primarily to increased salaries and related expenses.

 

Investment Income, net

 

Investment income for the three months ended September 30, 2015 and 2014 was $51,000 and $8,000, respectively.

 

Non-Cash Interest Expense on Liability Related to Sale of Future Royalty

 

In April 2015, Immunity Royalty Holdings, L.P. (IRH) purchased our right to receive 100% of the royalty payments on commercial sales of Kadcyla arising under our development and commercialization license with Genentech, until IRH has received aggregate royalties equal to $235 million or $260 million, depending on when the aggregate royalties received by IRH reach a specified milestone.  As described in Note C to our Consolidated Financial Statements, this royalty sale transaction has been recorded as a liability that amortizes over the estimated royalty payment period as Kadcyla royalties are remitted directly to the purchaser. We impute interest on the transaction and record interest expense at the effective interest rate, which we currently estimate to be 9.8%. There are a number of factors that could materially affect the estimated interest rate, in particular, the amount and timing of royalty payments from future net sales of Kadcyla, and we will assess this estimate on a periodic basis. As a result, future interest rates could differ significantly and any such change in interest rate will be adjusted prospectively.

 

Other Expense, net

 

Other expense, net for the three months ended September 30, 2015 and 2014 was $38,000 and $380,000, respectively. We incurred $44,000 and $381,000 in foreign currency exchange losses related to obligations with non-U.S. dollar-based suppliers and Euro cash balances maintained to fulfill them during the three months ended September 30, 2015 and 2014, respectively.

 

LIQUIDITY AND CAPITAL RESOURCES

 

 

 

As of

 

 

 

September 30,

 

June 30,

 

 

 

2015

 

2015

 

 

 

(In thousands)

 

Cash and cash equivalents

 

$

247,843

 

$

278,109

 

Shareholders’ equity

 

11,609

 

35,104

 

 

 

 

Three Months Ended September 30,

 

 

 

2015

 

2014

 

 

 

(In thousands)

 

Cash used for operating activities

 

$

(31,351

)

$

(18,899

)

Cash used for investing activities

 

(3,377

)

(1,708

)

Cash provided by financing activities

 

4,462

 

144

 

 

Cash Flows

 

We require cash to fund our operating expenses, including the advancement of our own clinical programs, and to make capital expenditures. Historically, we have funded our cash requirements primarily through equity financings in public markets and payments from our collaborators, including license fees, milestones, research funding and more recently, royalties. As of September 30, 2015, we had approximately $247.8 million in cash and cash equivalents. Net cash used for operations was $31.4 million and $18.9 million for the three months ended September 30, 2015 and 2014, respectively. The principal use of cash for operating activities for both periods presented was to fund our net loss.

 

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Net cash used for investing activities was $3.4 million and $1.7 million for the three months ended September 30, 2015 and 2014, respectively, and represents cash outflows for capital expenditures, primarily for the purchase of new equipment and leasehold improvements.

 

Net cash provided by financing activities was $4.5 million and $144,000 for the three months ended September 30, 2015 and 2014, respectively, which represents proceeds from the exercise of approximately 402,000 and 25,000 stock options, respectively.

 

In March 2015, we entered into a royalty purchase agreement with Immunity Royalty Holdings, L.P., which became effective on April 3, 2015, pursuant to which Immunity Royalty Holdings purchased our right to receive 100% of the royalty payments on commercial sales of Kadcyla® arising under our License Agreement with Genentech, Inc. dated as of May 2, 2000, as amended, until Immunity Royalty Holdings has received aggregate Kadcyla royalties equal to $235 million or $260 million, depending on when the aggregate Kadcyla royalties received by Immunity Royalty Holdings reach a specified milestone.  Once the applicable threshold is met, if ever, we will thereafter receive 85% and Immunity Royalty Holdings will receive 15% of the Kadcyla royalties for the remaining royalty term.  At consummation of the transaction in April 2015, we received gross cash proceeds of $200 million.  The Company recorded these cash proceeds as a deferred royalty obligation liability which will be amortized over the expected royalty recovery period.  As part of this transaction, the Company incurred approximately $5.9 million in transaction costs.

 

We anticipate that our current capital resources and expected future collaborator payments under existing collaborations will enable us to meet our operational expenses and capital expenditures through fiscal year 2017. However, we cannot provide assurance that such future collaborative agreement funding will, in fact, be received. Should we or our partners not meet some or all of the terms and conditions of our various collaboration agreements, we may be required to pursue additional strategic partners, secure alternative financing arrangements, and/or defer or limit some or all of our research, development and/or clinical projects.

 

Contractual Obligations

 

There have been no material changes to our contractual obligations during the current period from those disclosed in our Annual Report on Form 10-K for the fiscal year ended June 30, 2015.

 

Recent Accounting Pronouncements

 

In May 2014, the FASB issued Accounting Standards Update 2014-9, Revenue from Contracts with Customers (Topic 606), to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required us to adopt beginning in our first quarter of fiscal 2018. In July 2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.  Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. We are currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on our financial statements and related disclosures.

 

In August 2014, the FASB issued Accounting Standards Update 2014-15, Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern. This new standard gives a company’s management the final responsibilities to decide whether there’s substantial doubt about the company’s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company’s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for us on July 1, 2017. The adoption of this guidance is not expected to have a material impact on our consolidated financial statements.

 

In April 2015, the FASB issued Accounting Standards Update 2015-03, Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs. To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.  The recognition and measurement guidance for debt issuance costs are not affected by this update.  This guidance is effective for annual reporting beginning after December 15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for us on July 1, 2016. Our consolidated balance sheet as of September 30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.

 

23



Table of Contents

 

Forward-Looking Statements

 

This quarterly report includes forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These statements relate to analyses and other information which are based on forecasts of future results and estimates of amounts that are not yet determinable. These statements also relate to our future prospects, developments and business strategies.

 

These forward-looking statements can be identified by their use of terms and phrases, such as “anticipate,” “believe,” “could,” “estimate,” “expect,” “intend,” “may,” “plan,” “predict,” “project,” “will” and other similar terms and phrases, including references to assumptions. They may also use words such as “will,” “would,” “should,” “could” or “may”. These forward-looking statements involve known and unknown risks, uncertainties and other factors that may cause actual results to be materially different from those contemplated by our forward-looking statements. These known and unknown risks, uncertainties and other factors are described in detail in the “Risk Factors” section and in other sections of this Annual Report on Form 10-K for the year ended June 30, 2015. We disclaim any intention or obligation to update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

 

Kadcyla® is a registered trademark of Genentech, Inc., a member of the Roche Group.

Probody™ is a trademark of CytomX Therapeutics, Inc.

 

OFF-BALANCE SHEET ARRANGEMENTS

 

None.

 

ITEM 3.        Quantitative and Qualitative Disclosure about Market Risk

 

Our market risks, and the ways we manage them, are summarized in Part II, Item 7A, “Quantitative and Qualitative Disclosures About Market Risk” of our Annual Report on Form 10-K for the fiscal year ended June 30, 2015. Since then there have been no material changes to our market risks or to our management of such risks.

 

ITEM 4.      Controls and Procedures

 

(a)        Disclosure Controls and Procedures

 

The Company’s management, with the participation of its principal executive officer and principal financial officer, has evaluated the effectiveness of the Company’s disclosure controls and procedures (as defined in Rules 13a-15(e) or 15d-15(e) under the Securities Exchange Act of 1934, as amended (the “Exchange Act”)) as of the end of the period covered by this Quarterly Report on Form 10-Q. Based on such evaluation, the Company’s principal executive officer and principal financial officer have concluded that, as of the end of such period, the Company’s disclosure controls and procedures were adequate and effective.

 

(b)         Changes in Internal Controls

 

There have not been any changes in the Company’s internal control over financial reporting (as such term is defined in Rules 13a-15(f) and 15d-15(f) under the Exchange Act) during the quarter ended September 30, 2015 that have materially affected, or are reasonably likely to materially affect, the Company’s internal control over financial reporting.

 

PART II. OTHER INFORMATION

 

ITEM 1A.               Risk Factors

 

You should carefully review and consider the information regarding certain factors that could materially affect our business, financial condition or future results set forth under Item 1A. (Risk Factors) in our Annual Report on Form 10-K for the fiscal year ended June 30, 2015. There have been no material changes from the factors disclosed in our 2015 Annual Report on Form 10-K, although we may disclose changes to such factors or disclose additional factors from time to time in our future filings with the Securities and Exchange Commission.

 

24



Table of Contents

 

ITEM 6.                        Exhibits

 

Exhibit No.

 

Description

 

 

 

31.1

 

Certification of Principal Executive Officer under Section 302 of the Sarbanes-Oxley Act of 2002.

31.2

 

Certification of Principal Financial Officer under Section 302 of the Sarbanes-Oxley Act of 2002.

32†

 

Certifications of Principal Executive Officer and Principal Financial Officer under Section 906 of the Sarbanes-Oxley Act of 2002.

101.INS

 

XBRL Instance Document

101.SCH

 

XBRL Taxonomy Extension Schema

101.CAL

 

XBRL Taxonomy Extension Calculation Linkbase

101.DEF

 

XBRL Taxonomy Extension Definition Linkbase

101.LAB

 

XBRL Taxonomy Extension Label Linkbase

101.PRE

 

XBRL Taxonomy Extension Presentation Linkbase

 


                                         Furnished, not filed.

 

25



Table of Contents

 

SIGNATURES

 

Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the Registrant has duly caused this report to be signed on its behalf by the undersigned thereunto duly authorized.

 

 

 

 

ImmunoGen, Inc.

 

 

 

 

Date: October 30, 2015

 

By:

/s/ Daniel M. Junius

 

 

 

Daniel M. Junius

 

 

 

President, Chief Executive Officer (Principal Executive Officer)

 

 

 

 

Date: October 30, 2015

 

By:

/s/ David B. Johnston

 

 

 

David B. Johnston

 

 

 

Executive Vice President, Chief Financial Officer (Principal Financial and Accounting Officer)

 

26


EX-31.1 2 a15-18859_1ex31d1.htm EX-31.1

EXHIBIT 31.1

 

CERTIFICATIONS

 

I, Daniel Junius, certify that:

 

1.                                      I have reviewed this quarterly report on Form 10-Q of ImmunoGen, Inc.;

 

2.                                      Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 

3.                                      Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 

4.                                      The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

 

a)                                     designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

 

b)                                     designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted principles;

 

c)                                      evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

 

d)                                     disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

 

5.                                      The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

 

a)                                     all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

 

b)                                     any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

 

Date: October 30, 2015

 

/s/ Daniel M. Junius

 

Daniel M. Junius

 

President, Chief Executive Officer (Principal Executive Officer)

 

 


EX-31.2 3 a15-18859_1ex31d2.htm EX-31.2

EXHIBIT 31.2

 

CERTIFICATIONS

 

I, David B. Johnston, certify that:

 

1.                                      I have reviewed this quarterly report on Form 10-Q of ImmunoGen, Inc.;

 

2.                                      Based on my knowledge, this report does not contain any untrue statement of a material fact or omit to state a material fact necessary to make the statements made, in light of the circumstances under which such statements were made, not misleading with respect to the period covered by this report;

 

3.                                      Based on my knowledge, the financial statements, and other financial information included in this report, fairly present in all material respects the financial condition, results of operations and cash flows of the registrant as of, and for, the periods presented in this report;

 

4.                                      The registrant’s other certifying officer(s) and I are responsible for establishing and maintaining disclosure controls and procedures (as defined in Exchange Act Rules 13a-15(e) and 15d-15(e)) and internal control over financial reporting (as defined in Exchange Act Rules 13a-15(f) and 15d-15(f)) for the registrant and have:

 

a)                                     designed such disclosure controls and procedures, or caused such disclosure controls and procedures to be designed under our supervision, to ensure that material information relating to the registrant, including its consolidated subsidiaries, is made known to us by others within those entities, particularly during the period in which this report is being prepared;

 

b)                                     designed such internal control over financial reporting, or caused such internal control over financial reporting to be designed under our supervision, to provide reasonable assurance regarding the reliability of financial reporting and the preparation of financial statements for external purposes in accordance with generally accepted principles;

 

c)                                      evaluated the effectiveness of the registrant’s disclosure controls and procedures and presented in this report our conclusions about the effectiveness of the disclosure controls and procedures, as of the end of the period covered by this report based on such evaluation; and

 

d)                                     disclosed in this report any change in the registrant’s internal control over financial reporting that occurred during the registrant’s most recent fiscal quarter (the registrant’s fourth fiscal quarter in the case of an annual report) that has materially affected, or is reasonably likely to materially affect, the registrant’s internal control over financial reporting; and

 

5.                                      The registrant’s other certifying officer(s) and I have disclosed, based on our most recent evaluation of internal control over financial reporting, to the registrant’s auditors and the audit committee of the registrant’s board of directors (or persons performing the equivalent functions):

 

a)                                     all significant deficiencies and material weaknesses in the design or operation of internal control over financial reporting which are reasonably likely to adversely affect the registrant’s ability to record, process, summarize and report financial information; and

 

b)                                     any fraud, whether or not material, that involves management or other employees who have a significant role in the registrant’s internal control over financial reporting.

 

Date: October 30, 2015

 

/s/ David B. Johnston

 

David B. Johnston

 

Executive Vice President, Chief Financial Officer (Principal Financial and Accounting Officer)

 

 


EX-32 4 a15-18859_1ex32.htm EX-32

EXHIBIT 32

 

Certification

 

Pursuant to Section 906 of the Sarbanes-Oxley Act of 2002

 

(Subsections (a) and (b) of Section 1350, Chapter 63 of Title 18, United States Code)

 

Pursuant to section 906 of the Sarbanes-Oxley Act of 2002 (subsections (a) and (b) of section 1350, chapter 63 of title 18, United States Code), each of the undersigned officers of ImmunoGen, Inc., a Massachusetts corporation (the “Company”), does hereby certify, to such officer’s knowledge, that:

 

The Quarterly Report for the period ended September 30, 2015 (the “Form 10-Q”) of the Company fully complies with the requirements of Section 13(a) or 15(d) of the Securities Exchange Act of 1934, and the information contained in the Form 10-Q fairly presents, in all material respects, the financial condition and results of operations of the Company.

 

 

Dated: October 30, 2015

/s/ DANIEL M. JUNIUS

 

Daniel M. Junius

 

President, Chief Executive Officer

 

(Principal Executive Officer)

 

 

Dated: October 30, 2015

/s/ DAVID B. JOHNSTON

 

David B. Johnston

 

Executive Vice President, Chief Financial Officer

 

(Principal Financial and Accounting Officer)

 


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1000000 34000000 9000000 20000000 5000000 70000000 100000000 29000000 199000000 30500000 200500000 4000000 3000000 5000000 9000000 2 P6Y6M P18M P12M 3100000 7000000 P12Y P10Y P12Y P10Y 9.8 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Financial Instruments and Concentration of Credit Risk</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash and cash equivalents are primarily maintained with three financial institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and, therefore, bear minimal risk. The Company&#x2019;s cash equivalents consist of money market funds with underlying investments primarily being U.S. Government issued securities and high quality, short term commercial paper. Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash, cash equivalents and marketable securities. The Company held no marketable securities as of September&nbsp;30, 2015 and June&nbsp;30, 2015. The Company&#x2019;s investment policy, approved by the Board of Directors, limits the amount it may invest in any one type of investment, thereby reducing credit risk concentrations.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 646000 646000 6301000 6139000 -92000 -29000 P12M 0 337000 0 7906000 11862000 191756000 186967000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-weight:bold;font-size:10pt;">C.&nbsp;&nbsp;&nbsp;&nbsp;Liability Related to Sale of Future Royalties</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In April&nbsp;2015,&nbsp;Immunity Royalty Holdings, L.P. (IRH) purchased the right to receive 100% of the royalty payments on commercial sales of Kadcyla arising under the Company&#x2019;s development and commercialization license with Genentech, until IRH has received aggregate royalties equal to $235 million or $260 million, depending on when the aggregate royalties received by IRH reach a specified milestone.&nbsp;&nbsp;Once the applicable threshold is met, if ever, the Company will thereafter receive 85% and IRH will receive 15% of the Kadcyla royalties for the remaining royalty term.&nbsp;&nbsp;At consummation of the transaction in April&nbsp;2015, the Company received cash proceeds of $200 million.&nbsp;&nbsp;As part of this sale, the Company incurred $5.9 million of transaction costs, which are presented in the accompanying consolidated balance sheet as deferred financing costs and will be amortized to interest expense over the estimated life of the royalty purchase agreement.&nbsp;&nbsp;Although the Company sold its rights to receive royalties from the sales of Kadcyla, as a result of its ongoing involvement in the cash flows related to these royalties, the Company will continue to account for these royalties as revenue and recorded the $200 million in proceeds from this transaction as a liability related to sale of future royalties (Royalty Obligation) that will be amortized using the interest method over the estimated life of the royalty purchase agreement.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The following table shows the activity within the liability account during the three-month period ended September&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 86.00%;margin-left:36pt;"> <tr> <td valign="bottom" style="width:82.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Period&nbsp;from</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">June&nbsp;30,&nbsp;2015&nbsp;to</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Liability related to sale of future royalties &#x2014; beginning balance</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>199,662 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 20.2pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-cash Kadcyla&nbsp;royalty revenue</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,684 </td> <td valign="bottom" style="width:01.16%;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">)</font></p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 20.2pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-cash interest expense recognized</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,851 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Liability related to sale of future royalties &#x2014; ending balance</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>198,829 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As royalties are remitted to IRH, the balance of the Royalty Obligation will be effectively repaid over the life of the agreement.&nbsp;&nbsp;In order to determine the amortization of the Royalty Obligation, the Company is required to estimate the total amount of future royalty payments to be received and remitted to IRH as noted above over the life of the agreement. The sum of these amounts less the $200 million proceeds the Company received will be recorded as interest expense over the life of the Royalty Obligation. Since inception, the Company&#x2019;s estimate of this total interest expense resulted in an effective annual interest rate of 9.8%. The Company periodically assesses the estimated royalty payments to IRH and to the extent such payments are greater or less than its initial estimates, or the timing of such payments is materially different than its original estimates, the Company will prospectively adjust the amortization of the Royalty Obligation. There are a number of factors that could materially affect the amount and timing of royalty payments from Genentech, most of which are not within the Company&#x2019;s control. Such factors include, but are not limited to, changing standards of care, the introduction of competing products, manufacturing or other delays, biosimilar competition, patent protection, adverse events that result in governmental health authority imposed restrictions on the use of the drug products, significant changes in foreign exchange rates as the royalties remitted to IRH are made in U.S. dollars (USD) while significant portions of the underlying sales of Kadcyla are made in currencies other than USD, and other events or circumstances that could result in reduced royalty payments from Kadcyla, all of which would result in a reduction of non-cash royalty revenues and the non-cash interest expense over the life of the Royalty Obligation. Conversely, if sales of Kadcyla are more than expected, the non-cash royalty revenues and the non-cash interest expense recorded by the Company would be greater over the term of the Royalty Obligation.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In addition, the royalty purchase agreement grants IRH the right to receive certain reports and other information relating to the royalties and contains other representations and warranties, covenants and indemnification obligations that are customary for a transaction of this nature.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 6234000 1700000 6070000 1000000 2000000 4851000 5143000 5684000 5684000 1147000 1296000 1 1 1 2 3 3 3 3 2 3 1 1 4 1 1 3 5 5 1 2 1 2 2 3 P5Y P5Y P5Y 71300000 P5Y2M 2 1000000 1000000 1000000 1000000 500000 2000000 500000 776000 772000 1 1 0.85 0.15 260000000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The following table shows the activity within the liability account during the three-month period ended September&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:82.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Period&nbsp;from</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">June&nbsp;30,&nbsp;2015&nbsp;to</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Liability related to sale of future royalties &#x2014; beginning balance</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>199,662 </td> <td valign="bottom" style="width:01.14%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 20.2pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-cash Kadcyla&nbsp;royalty revenue</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(5,684 </td> <td valign="bottom" style="width:01.14%;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">)</font></p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 20.2pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-cash interest expense recognized</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>4,851 </td> <td valign="bottom" style="width:01.14%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:82.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Liability related to sale of future royalties &#x2014; ending balance</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>198,829 </td> <td valign="bottom" style="width:01.14%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 10564000 11494000 1 35000000 P2Y6M 1 P10Y 5900000 8138000 9689000 5088000 6812000 199662000 198829000 743108000 753349000 5300000 118000 5700000 82000 89000 7507 313823000 285584000 292180000 262016000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Basis of Presentation</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The accompanying unaudited consolidated financial statements at September&nbsp;30, 2015 and June&nbsp;30, 2015 and for the three months ended September&nbsp;30, 2015 and 2014 include the accounts of ImmunoGen,&nbsp;Inc., or the Company, and its wholly owned subsidiaries,&nbsp;ImmunoGen Securities Corp.,&nbsp;ImmunoGen Europe Limited and Hurricane, LLC. The consolidated financial statements include all of the adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation of the Company&#x2019;s financial position in accordance with accounting principles generally accepted in the U.S. for interim financial information. The June 30, 2015 condensed consolidated balance sheet data presented for comparative purposes was derived from our audited financial statements but certain information and footnote disclosures normally included in the Company&#x2019;s annual financial statements have been condensed or omitted. The preparation of interim financial statements requires the use of management&#x2019;s estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim financial statements and the reported amounts of revenues and expenditures during the reported periods. The results of the interim periods are not necessarily indicative of the results for the entire year. Accordingly, the interim financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company&#x2019;s Annual Report on Form&nbsp;10-K for the year ended June&nbsp;30, 2015.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 0 142261000 121798000 278109000 247843000 269304000 269304000 240643000 240643000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Cash and Cash Equivalents</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">All highly liquid financial instruments with maturities of three months or less when purchased are considered cash equivalents. As</font><font style="display:inline;font-size:10pt;"> of </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and June&nbsp;30, 2015, the Company held $247.8&nbsp;million and $278.1 million, respectively, in cash and money market funds consisting principally of U.S. Government-issued securities and high quality, short-term commercial paper which were classified as cash and cash equivalents.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt 0pt 0pt 32.4pt;text-indent: -32.4pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-weight:bold;font-size:10pt;">B.</font><font style="display:inline;font-weight:bold;font-size:10pt;;font-size: 10pt;font-family:Times New Roman;text-indent:0pt;margin-left:0pt;padding:0pt 26pt 0pt 0pt;"></font><font style="display:inline;font-size:8.5pt;"></font><font style="display:inline;font-weight:bold;font-size:10pt;">Collaborative Agreements</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Lilly</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Eli Lilly and Company (Lilly)</font><font style="display:inline;font-size:10pt;"> had the right to take three exclusive development and commercialization licenses under a right-to-test agreement established in December&nbsp;2011, and took these licenses prior to the expiration of the agreement in December&nbsp;2014. </font><font style="display:inline;font-size:10pt;">The Company received a $20&nbsp;million upfront payment in connection with the execution of the right-to-test agreement in 2011.&nbsp;&nbsp;Under the terms of this right-to-test agreement, the first license had no associated exercise fee, and the second and third licenses each had a $2 million exercise fee. The first development and commercialization license was taken in August&nbsp;2013 and the agreement was amended in December&nbsp;2013 to provide Lilly with an extension provision and retrospectively include a $2 million exercise fee for the first license in lieu of the fee due for either the second or third license. The second and third licenses were taken in December&nbsp;2014, with one including the $2 million exercise fee and the other not. Under the two licenses with the $2 million exercise fee, the Company is entitled to receive up to a total of $199&nbsp;million in milestone payments, plus royalties on the commercial sales of any resulting products.&nbsp;&nbsp;Under the license taken in December&nbsp;2014 without the exercise fee, the Company is entitled to receive up to a total of $200.5&nbsp;million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones&#x2014;$29&nbsp;million for the two development and commercialization licenses with the $2&nbsp;million exercise fee, and $30.5&nbsp;million for the one development and commercialization license with no exercise fee; regulatory milestones&#x2014;$70&nbsp;million in all cases; and sales milestones&#x2014;$100&nbsp;million in all cases.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In September&nbsp;2015, Lilly initiated Phase I, first-in-human clinical testing of its ADC product candidate, LY3076226, triggering a $5 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September&nbsp;30, 2015.&nbsp;&nbsp;The next payment the Company could receive would be either a $9 million milestone for commencement of a Phase II clinical trial under this license or a $5&nbsp;million development milestone payment with the commencement of a Phase&nbsp;I clinical trial under either of its other two licenses.&nbsp;&nbsp;At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company&#x2019;s expected involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive. The Company also is entitled to receive payments for delivery of cytotoxic agents to Lilly and research and development activities performed on behalf of Lilly. Lilly is responsible for the manufacturing, product development and marketing of any products resulting from this collaboration.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Amgen</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Under a now-expired right-to-test agreement, in September&nbsp;2009, November&nbsp;2009 and December&nbsp;2012, Amgen took three exclusive development and commercialization licenses, for which the Company received an exercise fee of $1&nbsp;million for each license taken. In May&nbsp;2013, Amgen took one non-exclusive development and commercialization license, for which the Company received an exercise fee of $500,000. In October&nbsp;2013, the non-exclusive license was amended and converted to an exclusive license, for which Amgen paid an additional $500,000 fee to the Company. Amgen has sublicensed its rights under this license to Oxford BioTherapeutics&nbsp;Ltd. For each development and commercialization license taken, the Company is entitled to receive up to a total of $34&nbsp;million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones per license are categorized as follows: development milestones&#x2014;$9&nbsp;million; regulatory milestones&#x2014;$20&nbsp;million; and sales milestones&#x2014;$5&nbsp;million. Amgen (or its sublicensee(s)) is responsible for the manufacturing, product development and marketing of any products resulting from these development and commercialization licenses.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In September&nbsp;2015, the IND application for its third ADC product candidate became effective, triggering a $1 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September&nbsp;30, 2015. In November&nbsp;2011, the IND applications to the FDA for its product candidates AMG 595 and AMG 172 became effective, which triggered two $1&nbsp;million milestone payments to the Company. The next potential milestone the Company will be entitled to receive under these three licenses will be a development milestone for the first dosing of a patient in a Phase&nbsp;II clinical trial, which will result in a $3&nbsp;million payment being due. The next potential milestone the Company will be entitled to receive under the May&nbsp;2013 license will be a $1&nbsp;million development milestone for an IND becoming effective. At the time of execution of each of these development and commercialization licenses, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company&#x2019;s past involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive.</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Sanofi</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In July&nbsp;2003, the Company entered into a broad collaboration agreement with Sanofi (formerly Aventis) to discover, develop and commercialize antibody-based products. The collaboration agreement provides Sanofi with worldwide development and commercialization rights to new antibody-based products directed to targets that are included in the collaboration, including the exclusive right to use the Company&#x2019;s maytansinoid ADC technology in the creation of products developed to these targets. The product candidates (targets) as of September&nbsp;30, 2015 in the collaboration include SAR650984 (CD38), SAR566658 (CA6), SAR408701 (CEACAM5) and one earlier-stage compound that has yet to be disclosed.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">We are entitled to receive milestone payments potentially totaling $21.5&nbsp;million, per target, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones&#x2014;$7.5&nbsp;million; and regulatory milestones&#x2014;$14&nbsp;million. Through September&nbsp;30, 2015, the Company has received and recognized an aggregate of $20.5&nbsp;million in milestone payments for compounds covered under this agreement now or in the past, including a $3 million development milestone related to initiation of a Phase IIb clinical trial (as defined in the agreement) for SAR650984 and a $1 million development milestone related to initiation of a Phase I clinical trial for SAR408701 which are included in license and milestone fee revenue for the three months ended September&nbsp;30, 2014.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In December&nbsp;2006, we entered into a right-to-test agreement with Sanofi. The agreement provides Sanofi with the right to (a)&nbsp;test the Company&#x2019;s maytansinoid ADC technology with Sanofi&#x2019;s antibodies to targets under a right-to-test, or research, license, (b)&nbsp;take exclusive options, with certain restrictions, to specified targets for specified option periods and (c)&nbsp;upon exercise of those options, take exclusive licenses to use the Company&#x2019;s maytansinoid ADC technology to develop and commercialize products directed to the specified targets on terms agreed upon at the inception of the right-to-test agreement. Sanofi no longer has the right to take additional options under the agreement, although multiple outstanding options remain in effect for the remainder of their respective option periods. For each development and commercialization license taken, the Company is entitled to receive an exercise fee of $2&nbsp;million and up to a total of $30&nbsp;million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones&#x2014;$10&nbsp;million; and regulatory milestones&#x2014;$20&nbsp;million.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In December&nbsp;2013, Sanofi took its first exclusive development and commercialization license under the right-to-test agreement, for which the Company received an exercise fee of $2&nbsp;million and was recognizing this amount as revenue ratably over the Company&#x2019;s estimated period of its substantial involvement. The Company had previously estimated this development period would conclude at the end of non-pivotal Phase II testing.&nbsp;&nbsp;During the first quarter of fiscal 2015, the Company determined it will not be substantially involved in the development and commercialization of the product based on Sanofi&#x2019;s current plans to develop and manufacture the product without the Company&#x2019;s assistance. As a result of this determination, we recognized the balance of the upfront exercise fee during the prior period.&nbsp;&nbsp;This change in estimate resulted in an increase to license and milestone fees of $1.7 million for the three months ended September&nbsp;30, 2014 compared to amounts that would have been recognized pursuant to the Company&#x2019;s previous estimate.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Pursuant to the license agreement noted above, in October&nbsp;2015, </font><font style="display:inline;font-size:10pt;">Sanofi</font><font style="display:inline;font-size:10pt;"> initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The next milestone payment the Company could receive would be a $4 million development milestone for commencement of a Phase IIb clinical trial (as defined in the agreement) under this license. At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company&#x2019;s past involvement in the research and manufacturing of Sanofi&#x2019;s product candidates, these milestones were deemed substantive.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">For additional information related to these agreements, as well as the Company&#x2019;s other significant collaborative agreements, please read Note C, </font><font style="display:inline;font-style:italic;font-size:10pt;">Agreements </font><font style="display:inline;font-size:10pt;">to our consolidated financial statements included within the Company&#x2019;s 2015 Form&nbsp;10-K.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-weight:bold;font-size:10pt;">E.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Commitments and Contingencies</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Leases</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Effective July&nbsp;27, 2007, the Company entered into a lease agreement with Intercontinental Fund&nbsp;III for the rental of approximately 89,000 square feet of laboratory and office space at 830 Winter Street, Waltham, MA through March&nbsp;2020. The Company uses this space for its corporate headquarters and other operations. In December&nbsp;2013, the Company modified its lease agreement at 830 Winter Street, Waltham, MA to include approximately 19,000 square feet of additional office space through 2020, concurrent with the remainder of the original lease term. As part of the lease amendment, the Company received a construction allowance of approximately $746,000 to build out office space to the Company&#x2019;s specifications. The Company obtained physical control of the additional space to begin construction in January&nbsp;2014. In April, 2014, the Company again modified its lease agreement at this site to extend the lease to 2026. The Company may extend the lease for two additional terms of five years. As part of this lease amendment, the Company received a construction allowance of approximately $1.1&nbsp;million to build out office space to the Company&#x2019;s specifications. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company also leases manufacturing and office space at 333 Providence Highway, Norwood, MA under an agreement through 2018 with an option to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Effective April&nbsp;2013, the Company entered into a lease agreement with River Ridge Limited Partnership for the rental of 7,507 square feet of additional office space at 100 River Ridge Drive, Norwood, MA. The initial term of the lease is for five years and two months commencing in July&nbsp;2013 with an option for the Company to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount. The Company entered into a sublease in December&nbsp;2014 for this space, effective January&nbsp;2015 through July&nbsp;2018.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The minimum rental commitments for the Company&#x2019;s facilities, including real estate taxes and other expenses, for the next five fiscal years and thereafter under the non-cancelable operating lease agreements discussed above are as follows (in&nbsp;thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 86.00%;margin-left:36pt;"> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2016&nbsp;(nine months&nbsp;remaining)</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,519 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2017</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,147 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2018</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,253 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2019</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,441 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2020</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,423 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Thereafter</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>38,857 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum lease payments</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>71,640 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum rental payments from sublease</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(340 </td> <td valign="bottom" style="width:01.16%;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">)</font></p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum lease payments, net</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>71,300 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">There are no obligations under capital leases as of September&nbsp;30, 2015, as all of the capital leases were single payment obligations which have all been made.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Collaborations</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company is contractually obligated to make potential future success-based development, regulatory or sales milestone payments in conjunction with certain collaborative agreements. These payments are contingent upon the occurrence of certain future events and, given the nature of these events, it is unclear when, if ever, the Company may be required to pay such amounts. Further, the timing of any future payment is not reasonably estimable. As of </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, the maximum amount that may be payable in the future under the Company&#x2019;s current collaborative agreements is $162&nbsp;million, $1.4&nbsp;million of which is reimbursable by a third party under a separate agreement.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 25.2pt;text-indent: -25.2pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 0.01 0.01 150000000 150000000 86579000 86981000 86579000 86981000 866000 870000 -22282000 -33740000 0.11 0.03 0.32 0.45 0.16 0.35 0.38 0.00 1159000 1136000 5300000 4415000 4147000 333000 858000 40855000 40794000 1389000 1127000 -0.26 -0.39 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Computation of Net Loss per Common Share</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Basic and diluted net loss per share is calculated based upon the weighted average number of common shares outstanding during the period. During periods of income, participating securities are allocated a proportional share of income determined by dividing total weighted average participating securities by the sum of the total weighted average common shares and participating securities (the &#x201C;two-class method&#x201D;). Shares of the Company&#x2019;s restricted stock participate in any dividends declared by the Company and are therefore considered to be participating securities. Participating securities have the effect of diluting both basic and diluted earnings per share during periods of income. During periods of loss, no loss is allocated to participating securities since they have no contractual obligation to share in the losses of the Company. Diluted (loss) income per share is computed after giving consideration to the dilutive effect of stock options and restricted stock that are outstanding during the period, except where such non-participating securities would be anti-dilutive.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;"> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:28.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Options outstanding to purchase common stock and unvested restricted stock (in thousands)</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11,494&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,564&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Common stock equivalents under treasury stock method</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,296&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,147&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s common stock equivalents have not been included in any net loss per share calculation because their effect is anti-dilutive due to the Company&#x2019;s net loss position.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 8346000 3262000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of September&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.&nbsp; The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of September&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;September&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of June&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of June&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;June&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Fair Value of Financial Instruments</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Fair value is defined under ASC Topic 820, &#x201C;Fair Value Measurements and Disclosures,&#x201D; as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date.&nbsp; Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs.&nbsp; The standard describes a fair value hierarchy to measure fair value which is based on three levels of inputs, of which the first two are considered observable and the last unobservable, as follows:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 1 - Quoted prices in active markets for identical assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of September&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.&nbsp; The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of September&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;September&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of June&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of June&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;June&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The fair value of the Company&#x2019;s cash equivalents is based primarily on quoted prices from active markets.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 6000 7095000 8329000 746000 1100000 138000 1551000 -58000 1724000 -2983000 464000 -3153000 -5084000 -835000 -1689000 29000 -871000 -105000 -62000 -525000 -95000 -545000 185000 2935000 1246000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Inventory</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Inventory costs relate to clinical trial materials being manufactured for sale to the Company&#x2019;s collaborators. Inventory is stated at the lower of cost or market as determined on a first-in, first-out (FIFO) basis.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Inventory at September&nbsp;30, 2015 and June&nbsp;30, 2015 is summarized below (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 86.00%;margin-left:36pt;"> <tr> <td valign="bottom" style="width:65.38%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">June&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Raw materials</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>76&nbsp; </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>279&nbsp; </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Work in process</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,170&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,656&nbsp; </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,246&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,935&nbsp; </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Raw materials inventory consists entirely of DM1 and DM4, proprietary cell-killing agents the Company developed as part of its ADC technology. The Company considers more than a twelve month supply of raw materials that is not supported by firm, fixed orders and/or projections from its collaborators to be excess and establishes a reserve to reduce to zero the value of any such excess raw material inventory with a corresponding charge to research and development expense. In accordance with this policy, the Company recorded no expense related to excess inventory during the three-month period ended September&nbsp;30, 2015 and $337,000 of expense during the three months ended September&nbsp;30, 2014.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Work in process inventory consists of conjugate manufactured for sale to the Company&#x2019;s collaborators to be used in preclinical and clinical studies.&nbsp;&nbsp;All conjugate is made to order at the request of the collaborators and subject to the terms and conditions of respective supply agreements.&nbsp;&nbsp;As such, no reserve for work in process inventory is required.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 279000 76000 2656000 1170000 8000 51000 278719000 273975000 313823000 285584000 35810000 35948000 0 0 -20463000 -30266000 144000 4462000 -1708000 -3377000 -18899000 -31351000 -22282000 -33740000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Recent Accounting Pronouncements</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In May&nbsp;2014, the FASB issued Accounting Standards Update 2014-9, </font><font style="display:inline;font-style:italic;font-size:10pt;">Revenue from Contracts with Customers (Topic 606) (&#x201C;ASU 2014-09&#x201D;),</font><font style="display:inline;font-size:10pt;"> to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required the Company to adopt beginning in its first quarter of fiscal 2018. In July&nbsp;2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.&nbsp;&nbsp;Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. The Company is currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on its consolidated financial statements and related disclosures.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In August&nbsp;2014, the FASB issued Accounting Standards Update 2014-15, </font><font style="display:inline;font-style:italic;font-size:10pt;">Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity&#x2019;s Ability to Continue as a Going Concern. </font><font style="display:inline;font-size:10pt;">This new standard gives a company&#x2019;s management the final responsibilities to decide whether there&#x2019;s substantial doubt about the company&#x2019;s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company&#x2019;s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December&nbsp;15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2017. The adoption of this guidance is not expected to have a material impact on the Company&#x2019;s consolidated financial statements.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In April&nbsp;2015, the FASB issued Accounting Standards Update 2015-03,&nbsp;</font><font style="display:inline;font-style:italic;font-size:10pt;">Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs.</font><font style="display:inline;font-size:10pt;"> To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.&nbsp;&nbsp;The recognition and measurement guidance for debt issuance costs are not affected by this update.&nbsp;&nbsp;This guidance is effective for annual reporting beginning after December&nbsp;15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2016. The Company&#x2019;s consolidated balance sheet as of September&nbsp;30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In July&nbsp;2015, the FASB issued Accounting Standards Update 2015-11, </font><font style="display:inline;font-style:italic;font-size:10pt;">Simplifying the Measurement of Inventory (Topic 330). </font><font style="display:inline;font-size:10pt;">T</font><font style="display:inline;font-size:10pt;">o simplify the principles for subsequent measurement of inventory, this new standard requires inventory measured using any method other than LIFO or the retail method shall be measured at the lower of cost and net realizable value, rather than lower of cost or market. This guidance is effective for annual reporting beginning after December&nbsp;15, 2016, including interim periods within the year of adoption, and calls for prospective application, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2017. The adoption of this guidance is not expected to have a material impact on the Company&#x2019;s consolidated financial statements.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 1 35113000 43461000 -21910000 -28610000 71640000 340000 6423000 6441000 7253000 7147000 38857000 5519000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="text-indent:0pt;margin-left:0pt; padding-right:26pt;"><font style="display:inline;font-weight:bold;font-size:10pt;">A.</font></font><font style="text-indent:0pt;margin-left:0pt; padding-right:4pt;text-align:left"><font style="display:inline;font-size:3pt;"></font><font style="display:inline;font-weight:bold;font-size:10pt;">Summary of Significant Accounting Policies</font></font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Basis of Presentation</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The accompanying unaudited consolidated financial statements at September&nbsp;30, 2015 and June&nbsp;30, 2015 and for the three months ended September&nbsp;30, 2015 and 2014 include the accounts of ImmunoGen,&nbsp;Inc., or the Company, and its wholly owned subsidiaries,&nbsp;ImmunoGen Securities Corp.,&nbsp;ImmunoGen Europe Limited and Hurricane, LLC. The consolidated financial statements include all of the adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation of the Company&#x2019;s financial position in accordance with accounting principles generally accepted in the U.S. for interim financial information. The June 30, 2015 condensed consolidated balance sheet data presented for comparative purposes was derived from our audited financial statements but certain information and footnote disclosures normally included in the Company&#x2019;s annual financial statements have been condensed or omitted. The preparation of interim financial statements requires the use of management&#x2019;s estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim financial statements and the reported amounts of revenues and expenditures during the reported periods. The results of the interim periods are not necessarily indicative of the results for the entire year. Accordingly, the interim financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company&#x2019;s Annual Report on Form&nbsp;10-K for the year ended June&nbsp;30, 2015.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Subsequent Events</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company has evaluated all events or transactions that occurred after September&nbsp;30, 2015 up through the date the Company issued these financial statements. </font><font style="display:inline;font-size:10pt;">In October&nbsp;2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. </font><font style="display:inline;font-size:10pt;">The Company did not have any other material recognizable or unrecognizable subsequent events during this period.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Revenue Recognition</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company enters into licensing and development agreements with collaborative partners for the development of monoclonal antibody-based anticancer therapeutics. The terms of these agreements contain multiple deliverables which may include (i)&nbsp;licenses, or options to obtain licenses, to the Company&#x2019;s antibody-drug conjugate, or ADC, technology, (ii)&nbsp;rights to future technological improvements, (iii)&nbsp;research activities to be performed on behalf of the collaborative partner, (iv)&nbsp;delivery of cytotoxic agents and (v)&nbsp;the manufacture of preclinical or clinical materials for the collaborative partner. Payments to the Company under these agreements may include upfront fees, option fees, exercise fees, payments for research activities, payments for the manufacture of preclinical or clinical materials, payments based upon the achievement of certain milestones and royalties on product sales. The Company follows the provisions of the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 605-25, &#x201C;Revenue Recognition&#x2014;Multiple-Element Arrangements,&#x201D; and ASC Topic 605-28, &#x201C;Revenue Recognition</font><font style="display:inline;font-weight:bold;font-size:10pt;">-</font><font style="display:inline;font-size:10pt;">Milestone Method,&#x201D; in accounting for these agreements. In order to account for these agreements, the Company must identify the deliverables included within the agreement and evaluate which deliverables represent separate units of accounting based on if certain criteria are met, including whether the delivered element has stand-alone value to the collaborator. The consideration received is allocated among the separate units of accounting, and the applicable revenue recognition criteria are applied to each of the separate units.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">At September&nbsp;30, 2015, the Company had the following two types of agreements with the parties identified below:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Development and commercialization licenses, which provide the party with the right to use the Company&#x2019;s ADC technology and/or certain other intellectual property to develop compounds to a specified antigen target:</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Amgen (four exclusive single-target licenses(1))</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Bayer HealthCare (one exclusive single-target license)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Biotest (one exclusive single-target license)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Lilly (three exclusive single-target licenses)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Times New Roman;font-size:10pt;;"> (1)</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Amgen has sublicensed one of its exclusive single-target licenses to Oxford BioTherapeutics Ltd.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Novartis (five exclusive single-target licenses and one license to two related targets: one target on an exclusive basis and the second target on a non-exclusive basis)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Roche, through its Genentech unit (five exclusive single-target licenses)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi (one exclusive single-target license and one exclusive license to multiple individual targets)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Research license/option agreement for a defined period of time to secure development and commercialization licenses to use the Company&#x2019;s ADC technology to develop anticancer compounds to specified targets on established terms (referred to herein as right-to-test agreements):</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">CytomX</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Takeda, through its wholly owned subsidiary, Millennium Pharmaceuticals,&nbsp;Inc.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">There are no performance, cancellation, termination or refund provisions in any of the arrangements that contain material financial consequences to the Company.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;text-decoration:underline;">Development and Commercialization Licenses</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The deliverables under a development and commercialization license agreement generally include the license to the Company&#x2019;s ADC technology with respect to a specified antigen target, and may also include deliverables related to rights to future technological improvements, research activities to be performed on behalf of the collaborative partner and the manufacture of preclinical or clinical materials for the collaborative partner.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Generally, development and commercialization licenses contain non-refundable terms for payments and, depending on the terms of the agreement, provide that the Company will (i)&nbsp;at the collaborator&#x2019;s request, provide research services at negotiated prices which are generally consistent with what other third parties would charge, (ii)&nbsp;at the collaborator&#x2019;s request, manufacture and provide to it preclinical and clinical materials or deliver cytotoxic agents at negotiated prices which are generally consistent with what other third parties would charge, (iii)&nbsp;earn payments upon the achievement of certain milestones and (iv)&nbsp;earn royalty payments, generally until the later of the last applicable patent expiration or 10 to 12&nbsp;years after product launch. In the case of Kadcyla, however, the minimum royalty term is 10 years and the maximum royalty term is 12 years on a country by country basis, regardless of patent protection.&nbsp;&nbsp;Royalty rates may vary over the royalty term depending on the Company&#x2019;s intellectual property rights and/or the presence of comparable competing products. The Company may provide technical assistance and share any technology improvements with its collaborators during the term of the collaboration agreements. The Company does not directly control when or whether any collaborator will request research or manufacturing services, achieve milestones or become liable for royalty payments. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In determining the units of accounting, management evaluates whether the license has stand-alone value from the undelivered elements to the collaborative partner based on the consideration of the relevant facts and circumstances for each arrangement. Factors considered in this determination include the research capabilities of the partner and the availability of ADC technology research expertise in the general marketplace. If the Company concludes that the license has stand-alone value and therefore will be accounted for as a separate unit of accounting, the Company then determines the estimated selling prices of the license and all other units of accounting based on market conditions, similar arrangements entered into by third parties, and entity-specific factors such as the terms of the Company&#x2019;s previous collaborative agreements, recent preclinical and clinical testing results of therapeutic products that use the Company&#x2019;s ADC technology, the Company&#x2019;s pricing practices and pricing objectives, the likelihood that technological improvements will be made, and, if made, will be used by the Company&#x2019;s collaborators and the nature of the research services to be performed on behalf of its collaborators and market rates for similar services.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Upfront payments on development and commercialization licenses are deferred if facts and circumstances dictate that the license does not have stand-alone value. Prior to the adoption of Accounting Standards Update (ASU) No.&nbsp;2009-13, &#x201C;Revenue Arrangements with Multiple Deliverables&#x201D; on July&nbsp;1, 2010, the Company determined that its licenses lacked stand-alone value and were combined with other elements of the arrangement and any amounts associated with the license were deferred and amortized over a certain period, which the Company refers to as the Company&#x2019;s period of substantial involvement. The determination of the length of the period over which to defer revenue is subject to judgment and estimation and can have an impact on the amount of revenue recognized in a given period. Historically the Company&#x2019;s involvement with the development of a collaborator&#x2019;s product candidate has been significant at the early stages of development, and lessens as it progresses into clinical trials. Also, as a drug candidate gets closer to commencing pivotal testing the Company&#x2019;s collaborators have sought an alternative site to manufacture their products, as the Company&#x2019;s facility does not produce pivotal or commercial drug product. Accordingly, the Company generally estimates this period of substantial involvement to begin at the inception of the collaboration agreement and conclude at the end of non-pivotal Phase&nbsp;II testing. The Company believes this period of substantial involvement is, depending on the nature of the license, on average six and one-half years. Quarterly, the Company reassesses its periods of substantial involvement over which the Company amortizes its upfront license fees and makes adjustments as appropriate. In the event a collaborator elects to discontinue development of a specific product candidate under a development and commercialization license, but retains its right to use the Company&#x2019;s technology to develop an alternative product candidate to the same target or a target substitute, the Company would cease amortization of any remaining portion of the upfront fee until there is substantial preclinical activity on another product candidate and its remaining period of substantial involvement can be estimated. In the event that a development and commercialization license were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Subsequent to the adoption of ASU No.&nbsp;2009-13, the Company determined that its research licenses lack stand-alone value and are considered for aggregation with the other elements of the arrangement and accounted for as one unit of accounting.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Upfront payments on development and commercialization licenses may be recognized upon delivery of the license if facts and circumstances dictate that the license has stand-alone value from the undelivered elements, which generally include rights to future technological improvements, research services, delivery of cytotoxic agents and the manufacture of preclinical and clinical materials.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company recognizes revenue related to research services that represent separate units of accounting as they are performed, as long as there is persuasive evidence of an arrangement, the fee is fixed or determinable, and collection of the related receivable is probable. The Company recognizes revenue related to the rights to future technological improvements over the estimated term of the applicable license.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company may also provide cytotoxic agents to its collaborators or produce preclinical and clinical materials at negotiated prices which are generally consistent with what other third parties would charge. The Company recognizes revenue on cytotoxic agents and on preclinical and clinical materials when the materials have passed all quality testing required for collaborator acceptance and title and risk of loss have transferred to the collaborator. Arrangement consideration allocated to the manufacture of preclinical and clinical materials in a multiple-deliverable arrangement is below the Company&#x2019;s full cost, and the Company&#x2019;s full cost is not expected to ever be below its contract selling prices for its existing collaborations. During the three months ended September&nbsp;30, 2015 and 2014, the difference between the Company&#x2019;s full cost to manufacture preclinical and clinical materials on behalf of its collaborators as compared to total amounts received from collaborators for the manufacture of preclinical and clinical materials was $7.0 million and $3.1 million, respectively. The majority of the Company&#x2019;s costs to produce these preclinical and clinical materials are fixed and then allocated to each batch based on the number of batches produced during the period. Therefore, the Company&#x2019;s costs to produce these materials are significantly impacted by the number of batches produced during the period. The volume of preclinical and clinical materials the Company produces is directly related to the number of clinical trials the Company and its collaborators are preparing for or currently have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period such trials last. Accordingly, the volume of preclinical and clinical materials produced, and therefore the Company&#x2019;s per-batch costs to manufacture these preclinical and clinical materials, may vary significantly from period to period.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company may also produce research material for potential collaborators under material transfer agreements. Additionally, the Company performs research activities, including developing antibody specific conjugation processes, on behalf of its collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The Company records amounts received for research materials produced or services performed as a component of research and development support revenue. The Company also develops conjugation processes for materials for later-stage testing and commercialization for certain collaborators. The Company is compensated at negotiated rates and may receive milestone payments for developing these processes which are recorded as a component of research and development support revenue.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s development and commercialization license agreements have milestone payments which for reporting purposes are aggregated into three categories: (i)&nbsp;development milestones, (ii)&nbsp;regulatory milestones, and (iii)&nbsp;sales milestones. Development milestones are typically payable when a product candidate initiates or advances into different clinical trial phases. Regulatory milestones are typically payable upon submission for marketing approval with the U.S. Food and Drug Administration, or FDA, or other countries&#x2019; regulatory authorities or on receipt of actual marketing approvals for the compound or for additional indications. Sales milestones are typically payable when annual sales reach certain levels.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">At the inception of each agreement that includes milestone payments, the Company evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a)&nbsp;the consideration is commensurate with either (1)&nbsp;the entity&#x2019;s performance to achieve the milestone, or (2)&nbsp;the enhancement of the value of the delivered item(s)&nbsp;as a result of a specific outcome resulting from the entity&#x2019;s performance to achieve the milestone, (b)&nbsp;the consideration relates solely to past performance and (c)&nbsp;the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. The Company evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-refundable development and regulatory milestones that are expected to be achieved as a result of the Company&#x2019;s efforts during the period of substantial involvement are considered substantive and are recognized as revenue upon the achievement of the milestone, assuming all other revenue recognition criteria are met. Milestones that are not considered substantive because the Company does not contribute effort to the achievement of such milestones are generally achieved after the period of substantial involvement and are recognized as revenue upon achievement of the milestone, as there are no undelivered elements remaining and no continuing performance obligations, assuming all other revenue recognition criteria are met.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Under the Company&#x2019;s development and commercialization license agreements, the Company receives royalty payments based upon its licensees&#x2019; net sales of covered products. Generally, under these agreements the Company is to receive royalty reports and payments from its licensees approximately one quarter in arrears, that is, generally in the third month of the quarter after the licensee has sold the royalty-bearing product or products. The Company recognizes royalty revenues when it can reliably estimate such amounts and collectability is reasonably assured. As such, the Company generally recognizes royalty revenues in the quarter reported to the Company by its licensees, or one quarter following the quarter in which sales by the Company&#x2019;s licensees occurred.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;text-decoration:underline;">Right-to-Test Agreements</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s right-to-test agreements provide collaborators the right to (a)&nbsp;test the Company&#x2019;s ADC technology for a defined period of time through a research, or right-to-test, license, (b)&nbsp;take options, for a defined period of time, to specified targets and (c)&nbsp;upon exercise of those options, secure or &#x201C;take&#x201D; licenses to develop and commercialize products for the specified targets on established terms. Under these agreements, fees may be due to the Company (i)&nbsp;at the inception of the arrangement (referred to as &#x201C;upfront&#x201D; fees or payments), (ii)&nbsp;upon taking an option with respect to a specific target (referred to as option fees or payments earned, if any, when the option is &#x201C;taken&#x201D;), (iii)&nbsp;upon the exercise of a previously taken option to acquire a development and commercialization license(s)&nbsp;(referred to as exercise fees or payments earned, if any, when the development and commercialization license is &#x201C;taken&#x201D;), or (iv)&nbsp;some combination of all of these fees.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The accounting for right-to-test agreements is dependent on the nature of the options granted to the collaborative partner. Options are considered substantive if, at the inception of a right-to-test agreement, the Company is at risk as to whether the collaborative partner will choose to exercise the options to secure development and commercialization licenses. Factors that are considered in evaluating whether options are substantive include the overall objective of the arrangement, the benefit the collaborator might obtain from the agreement without exercising the options, the cost to exercise the options relative to the total upfront consideration, and the additional financial commitments or economic penalties imposed on the collaborator as a result of exercising the options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">For right-to-test agreements where the options to secure development and commercialization licenses to the Company&#x2019;s ADC technology are considered substantive, the Company does not consider the development and commercialization licenses to be a deliverable at the inception of the agreement. For those right-to-test agreements entered into prior to the adoption of ASU No.&nbsp;2009-13 where the options to secure development and commercialization licenses are considered substantive, the Company has deferred the upfront payments received and recognizes this revenue over the period during which the collaborator could elect to take options for development and commercialization licenses. These periods are specific to each collaboration agreement. If a collaborator takes an option to acquire a development and commercialization license under these agreements, any substantive option fee is deferred and recognized over the life of the option, generally 12 to 18&nbsp;months. If a collaborator exercises an option and takes a development and commercialization license to a specific target, the Company attributes the exercise fee to the development and commercialization license. Upon exercise of an option to acquire a development and commercialization license, the Company would also attribute any remaining deferred option fee to the development and commercialization license and apply the multiple-element revenue recognition criteria to the development and commercialization license and any other deliverables to determine the appropriate revenue recognition, which will be consistent with the Company&#x2019;s accounting policy for upfront payments on single-target licenses. In the event a right-to-test agreement were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination. None of the Company&#x2019;s right-to-test agreements entered into subsequent to the adoption of ASU No.&nbsp;2009-13 has been determined to contain substantive options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">For right-to-test agreements where the options to secure development and commercialization licenses to the Company&#x2019;s ADC technology are not considered substantive, the Company considers the development and commercialization licenses to be a deliverable at the inception of the agreement and applies the multiple-element revenue recognition criteria to determine the appropriate revenue recognition. None of the Company&#x2019;s right-to-test agreements entered into prior to the adoption of ASU No.&nbsp;2009-13 has been determined to contain non-substantive options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company does not directly control when or if any collaborator will exercise its options for development and commercialization licenses. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Financial Instruments and Concentration of Credit Risk</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash and cash equivalents are primarily maintained with three financial institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and, therefore, bear minimal risk. The Company&#x2019;s cash equivalents consist of money market funds with underlying investments primarily being U.S. Government issued securities and high quality, short term commercial paper. Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash, cash equivalents and marketable securities. The Company held no marketable securities as of September&nbsp;30, 2015 and June&nbsp;30, 2015. The Company&#x2019;s investment policy, approved by the Board of Directors, limits the amount it may invest in any one type of investment, thereby reducing credit risk concentrations.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Cash and Cash Equivalents</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">All highly liquid financial instruments with maturities of three months or less when purchased are considered cash equivalents. As</font><font style="display:inline;font-size:10pt;"> of </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and June&nbsp;30, 2015, the Company held $247.8&nbsp;million and $278.1 million, respectively, in cash and money market funds consisting principally of U.S. Government-issued securities and high quality, short-term commercial paper which were classified as cash and cash equivalents.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Fair Value of Financial Instruments</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Fair value is defined under ASC Topic 820, &#x201C;Fair Value Measurements and Disclosures,&#x201D; as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date.&nbsp; Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs.&nbsp; The standard describes a fair value hierarchy to measure fair value which is based on three levels of inputs, of which the first two are considered observable and the last unobservable, as follows:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 1 - Quoted prices in active markets for identical assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of September&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.&nbsp; The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of September&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;September&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>240,643&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of June&nbsp;30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company&#x2019;s financial assets measured at fair value on a recurring basis as of June&nbsp;30, 2015 (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="11" valign="bottom" style="width:58.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Fair&nbsp;Value&nbsp;Measurements&nbsp;at&nbsp;June&nbsp;30,&nbsp;2015&nbsp;Using</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Quoted&nbsp;Prices&nbsp;in</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Active&nbsp;Markets&nbsp;for</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Identical&nbsp;Assets</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant&nbsp;Other</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Observable&nbsp;Inputs</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Significant</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Unobservable</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">Inputs</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:38.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Total</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:14.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;1)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;2)</font></p> </td> <td valign="bottom" style="width:02.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:12.00%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">(Level&nbsp;3)</font></p> </td> <td valign="bottom" style="width:01.00%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:38.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Cash equivalents</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>269,304&nbsp; </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:11.88%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:02.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:01.00%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The fair value of the Company&#x2019;s cash equivalents is based primarily on quoted prices from active markets.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Unbilled Revenue</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The majority of the Company&#x2019;s unbilled revenue at September&nbsp;30, 2015 and June&nbsp;30, 2015 represents research funding earned prior to those dates based on actual resources utilized under the Company&#x2019;s agreements with various collaborators.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Inventory</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Inventory costs relate to clinical trial materials being manufactured for sale to the Company&#x2019;s collaborators. Inventory is stated at the lower of cost or market as determined on a first-in, first-out (FIFO) basis.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Inventory at September&nbsp;30, 2015 and June&nbsp;30, 2015 is summarized below (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 86.00%;margin-left:36pt;"> <tr> <td valign="bottom" style="width:65.38%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">June&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Raw materials</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>76&nbsp; </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>279&nbsp; </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Work in process</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,170&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,656&nbsp; </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.84%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.38%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,246&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,935&nbsp; </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Raw materials inventory consists entirely of DM1 and DM4, proprietary cell-killing agents the Company developed as part of its ADC technology. The Company considers more than a twelve month supply of raw materials that is not supported by firm, fixed orders and/or projections from its collaborators to be excess and establishes a reserve to reduce to zero the value of any such excess raw material inventory with a corresponding charge to research and development expense. In accordance with this policy, the Company recorded no expense related to excess inventory during the three-month period ended September&nbsp;30, 2015 and $337,000 of expense during the three months ended September&nbsp;30, 2014.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Work in process inventory consists of conjugate manufactured for sale to the Company&#x2019;s collaborators to be used in preclinical and clinical studies.&nbsp;&nbsp;All conjugate is made to order at the request of the collaborators and subject to the terms and conditions of respective supply agreements.&nbsp;&nbsp;As such, no reserve for work in process inventory is required.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Computation of Net Loss per Common Share</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Basic and diluted net loss per share is calculated based upon the weighted average number of common shares outstanding during the period. During periods of income, participating securities are allocated a proportional share of income determined by dividing total weighted average participating securities by the sum of the total weighted average common shares and participating securities (the &#x201C;two-class method&#x201D;). Shares of the Company&#x2019;s restricted stock participate in any dividends declared by the Company and are therefore considered to be participating securities. Participating securities have the effect of diluting both basic and diluted earnings per share during periods of income. During periods of loss, no loss is allocated to participating securities since they have no contractual obligation to share in the losses of the Company. Diluted (loss) income per share is computed after giving consideration to the dilutive effect of stock options and restricted stock that are outstanding during the period, except where such non-participating securities would be anti-dilutive.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 80.00%;margin-left:54pt;"> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:28.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Options outstanding to purchase common stock and unvested restricted stock (in thousands)</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11,494&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,564&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Common stock equivalents under treasury stock method</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,296&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,147&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s common stock equivalents have not been included in any net loss per share calculation because their effect is anti-dilutive due to the Company&#x2019;s net loss position.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Stock-Based Compensation</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of September&nbsp;30, 2015, the Company is authorized to grant future awards under one employee share-based compensation plan, which is the ImmunoGen,&nbsp;Inc. 2006 Employee, Director and Consultant Equity Incentive Plan, or the 2006 Plan. At the annual meeting of shareholders on November&nbsp;11, 2014, an amendment to the 2006 Plan was approved and an additional 5,500,000 shares were authorized for issuance under this plan.&nbsp;&nbsp;As amended, the 2006 Plan provides for the issuance of Stock Grants, the grant of Options and the grant of Stock-Based Awards for up to 17,500,000 shares of the Company&#x2019;s common stock, as well as 1,676,599 shares of common stock which represent awards granted under the previous stock option plan, the ImmunoGen,&nbsp;Inc. Restated Stock Option Plan, or the Former Plan, that were forfeited, expired or were cancelled without delivery of shares of common stock or which resulted in the forfeiture of shares of common stock back to the Company between November&nbsp;11, 2006 and June&nbsp;30, 2014. Option awards are granted with an exercise price equal to the market price of the Company&#x2019;s stock at the date of grant. Options vest at various periods of up to four years and may be exercised within ten years of the date of grant.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The stock-based awards are accounted for under ASC Topic 718, &#x201C;Compensation&#x2014;Stock Compensation.&#x201D; Pursuant to Topic 718, the estimated grant date fair value of awards is charged to the statement of operations and comprehensive loss over the requisite service period, which is the vesting period. Such amounts have been reduced by an estimate of forfeitures of all unvested awards. The fair value of each stock option is estimated on the date of grant using the Black-Scholes option-pricing model with the assumptions noted in the following table. As the Company has not paid dividends since inception, nor does it expect to pay any dividends for the foreseeable future, the expected dividend yield assumption is zero. Expected volatility is based exclusively on historical volatility data of the Company&#x2019;s stock. The expected term of stock options granted is based exclusively on historical data and represents the period of time that stock options granted are expected to be outstanding. The expected term is calculated for and applied to one group of stock options as the Company does not expect substantially different exercise or post-vesting termination behavior among its option recipients. The risk-free rate of the stock options is based on the U.S. Treasury rate in effect at the time of grant for the expected term of the stock options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;"> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Dividend</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Volatility</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>67.07&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>60.44&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Risk-free interest rate</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.89&nbsp; </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.88&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Expected life (years)</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Using the Black-Scholes option-pricing model, the weighted average grant date fair values of options granted during the three months ended September&nbsp;30, 2015 and 2014 were $10.31 and $6.27 per share, respectively.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Stock compensation expense related to stock options and restricted stock awards granted under the 2006 Plan was $5.7 million and $5.3 million during the three months ended September&nbsp;30, 2015 and 2014, respectively. As of September&nbsp;30, 2015, the estimated fair value of unvested employee awards was $35 million, net of estimated forfeitures. The weighted-average remaining vesting period for these awards is approximately two and a half years.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, holders of options issued under the Company&#x2019;s equity plans exercised their rights to acquire an aggregate of approximately 402,000 shares of common stock at prices ranging from $3.19 to $17.00 per share.&nbsp; The total proceeds to the Company from these option exercises were approximately $4.5 million.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Segment Information</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, the Company continued to operate in one operating segment which is the business of discovery of monoclonal antibody-based anticancer therapeutics.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The percentages of revenues recognized from significant customers of the Company in the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and 2014 are included in the following table:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;"> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Collaborative&nbsp;Partner:</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Biotest</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>16&nbsp; </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Lilly</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>35&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>45&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Roche</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>38&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>32&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">There were no other customers of the Company with significant revenues in the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and 2014.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Recent Accounting Pronouncements</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In May&nbsp;2014, the FASB issued Accounting Standards Update 2014-9, </font><font style="display:inline;font-style:italic;font-size:10pt;">Revenue from Contracts with Customers (Topic 606) (&#x201C;ASU 2014-09&#x201D;),</font><font style="display:inline;font-size:10pt;"> to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required the Company to adopt beginning in its first quarter of fiscal 2018. In July&nbsp;2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.&nbsp;&nbsp;Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. The Company is currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on its consolidated financial statements and related disclosures.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In August&nbsp;2014, the FASB issued Accounting Standards Update 2014-15, </font><font style="display:inline;font-style:italic;font-size:10pt;">Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity&#x2019;s Ability to Continue as a Going Concern. </font><font style="display:inline;font-size:10pt;">This new standard gives a company&#x2019;s management the final responsibilities to decide whether there&#x2019;s substantial doubt about the company&#x2019;s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company&#x2019;s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December&nbsp;15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2017. The adoption of this guidance is not expected to have a material impact on the Company&#x2019;s consolidated financial statements.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In April&nbsp;2015, the FASB issued Accounting Standards Update 2015-03,&nbsp;</font><font style="display:inline;font-style:italic;font-size:10pt;">Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs.</font><font style="display:inline;font-size:10pt;"> To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.&nbsp;&nbsp;The recognition and measurement guidance for debt issuance costs are not affected by this update.&nbsp;&nbsp;This guidance is effective for annual reporting beginning after December&nbsp;15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2016. The Company&#x2019;s consolidated balance sheet as of September&nbsp;30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In July&nbsp;2015, the FASB issued Accounting Standards Update 2015-11, </font><font style="display:inline;font-style:italic;font-size:10pt;">Simplifying the Measurement of Inventory (Topic 330). </font><font style="display:inline;font-size:10pt;">T</font><font style="display:inline;font-size:10pt;">o simplify the principles for subsequent measurement of inventory, this new standard requires inventory measured using any method other than LIFO or the retail method shall be measured at the lower of cost and net realizable value, rather than lower of cost or market. This guidance is effective for annual reporting beginning after December&nbsp;15, 2016, including interim periods within the year of adoption, and calls for prospective application, with early application permitted. Accordingly, the standard is effective for the Company on July&nbsp;1, 2017. The adoption of this guidance is not expected to have a material impact on the Company&#x2019;s consolidated financial statements.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 10441000 9631000 974000 911000 3997000 4127000 -380000 -38000 393000 1708000 3377000 0.01 0.01 5000000 5000000 0 0 0 0 4175000 4080000 20500000 20000000 1000000 3000000 5000000 200000000 144000 4462000 4500000 16254000 18510000 2027000 2325000 28018000 35132000 -708870000 -742610000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Revenue Recognition</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company enters into licensing and development agreements with collaborative partners for the development of monoclonal antibody-based anticancer therapeutics. The terms of these agreements contain multiple deliverables which may include (i)&nbsp;licenses, or options to obtain licenses, to the Company&#x2019;s antibody-drug conjugate, or ADC, technology, (ii)&nbsp;rights to future technological improvements, (iii)&nbsp;research activities to be performed on behalf of the collaborative partner, (iv)&nbsp;delivery of cytotoxic agents and (v)&nbsp;the manufacture of preclinical or clinical materials for the collaborative partner. Payments to the Company under these agreements may include upfront fees, option fees, exercise fees, payments for research activities, payments for the manufacture of preclinical or clinical materials, payments based upon the achievement of certain milestones and royalties on product sales. The Company follows the provisions of the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 605-25, &#x201C;Revenue Recognition&#x2014;Multiple-Element Arrangements,&#x201D; and ASC Topic 605-28, &#x201C;Revenue Recognition</font><font style="display:inline;font-weight:bold;font-size:10pt;">-</font><font style="display:inline;font-size:10pt;">Milestone Method,&#x201D; in accounting for these agreements. In order to account for these agreements, the Company must identify the deliverables included within the agreement and evaluate which deliverables represent separate units of accounting based on if certain criteria are met, including whether the delivered element has stand-alone value to the collaborator. The consideration received is allocated among the separate units of accounting, and the applicable revenue recognition criteria are applied to each of the separate units.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">At September&nbsp;30, 2015, the Company had the following two types of agreements with the parties identified below:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 00.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:18pt;"><p style="width:18pt;width:18pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Development and commercialization licenses, which provide the party with the right to use the Company&#x2019;s ADC technology and/or certain other intellectual property to develop compounds to a specified antigen target:</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Amgen (four exclusive single-target licenses(1))</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Bayer HealthCare (one exclusive single-target license)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Biotest (one exclusive single-target license)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Lilly (three exclusive single-target licenses)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:0pt;"><p style="width:0pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Times New Roman;font-size:10pt;;"> (1)</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Amgen has sublicensed one of its exclusive single-target licenses to Oxford BioTherapeutics Ltd.</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-align:center;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <a name="mrllPB2"></a><font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Novartis (five exclusive single-target licenses and one license to two related targets: one target on an exclusive basis and the second target on a non-exclusive basis)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Roche, through its Genentech unit (five exclusive single-target licenses)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi (one exclusive single-target license and one exclusive license to multiple individual targets)</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%"><table style="width:100%;" cellpadding="0" cellspacing="0"><tr><td style="width:36pt;"><p style="width:36pt;font-size:0pt;"></p></td><td valign="top" align="left" style="width: 18.00pt; display: inline;"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="margin:0pt;font-family:Symbol;font-size:10pt;;"> &#xB7;</font> </p> </td><td style="width:0pt;"><p style="width:0pt;width:0pt;font-size:0pt;"></p></td><td align="left" valign="top"> <p style="font-family:Times New Roman;font-size: 10pt;margin:0pt;"> <font style="display:inline;font-size:10pt;color:#000000;">Research license/option agreement for a defined period of time to secure development and commercialization licenses to use the Company&#x2019;s ADC technology to develop anticancer compounds to specified targets on established terms (referred to herein as right-to-test agreements):</font></p></td></tr></table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">CytomX</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 72pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Takeda, through its wholly owned subsidiary, Millennium Pharmaceuticals,&nbsp;Inc.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">There are no performance, cancellation, termination or refund provisions in any of the arrangements that contain material financial consequences to the Company.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;text-decoration:underline;">Development and Commercialization Licenses</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The deliverables under a development and commercialization license agreement generally include the license to the Company&#x2019;s ADC technology with respect to a specified antigen target, and may also include deliverables related to rights to future technological improvements, research activities to be performed on behalf of the collaborative partner and the manufacture of preclinical or clinical materials for the collaborative partner.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Generally, development and commercialization licenses contain non-refundable terms for payments and, depending on the terms of the agreement, provide that the Company will (i)&nbsp;at the collaborator&#x2019;s request, provide research services at negotiated prices which are generally consistent with what other third parties would charge, (ii)&nbsp;at the collaborator&#x2019;s request, manufacture and provide to it preclinical and clinical materials or deliver cytotoxic agents at negotiated prices which are generally consistent with what other third parties would charge, (iii)&nbsp;earn payments upon the achievement of certain milestones and (iv)&nbsp;earn royalty payments, generally until the later of the last applicable patent expiration or 10 to 12&nbsp;years after product launch. In the case of Kadcyla, however, the minimum royalty term is 10 years and the maximum royalty term is 12 years on a country by country basis, regardless of patent protection.&nbsp;&nbsp;Royalty rates may vary over the royalty term depending on the Company&#x2019;s intellectual property rights and/or the presence of comparable competing products. The Company may provide technical assistance and share any technology improvements with its collaborators during the term of the collaboration agreements. The Company does not directly control when or whether any collaborator will request research or manufacturing services, achieve milestones or become liable for royalty payments. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In determining the units of accounting, management evaluates whether the license has stand-alone value from the undelivered elements to the collaborative partner based on the consideration of the relevant facts and circumstances for each arrangement. Factors considered in this determination include the research capabilities of the partner and the availability of ADC technology research expertise in the general marketplace. If the Company concludes that the license has stand-alone value and therefore will be accounted for as a separate unit of accounting, the Company then determines the estimated selling prices of the license and all other units of accounting based on market conditions, similar arrangements entered into by third parties, and entity-specific factors such as the terms of the Company&#x2019;s previous collaborative agreements, recent preclinical and clinical testing results of therapeutic products that use the Company&#x2019;s ADC technology, the Company&#x2019;s pricing practices and pricing objectives, the likelihood that technological improvements will be made, and, if made, will be used by the Company&#x2019;s collaborators and the nature of the research services to be performed on behalf of its collaborators and market rates for similar services.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Upfront payments on development and commercialization licenses are deferred if facts and circumstances dictate that the license does not have stand-alone value. Prior to the adoption of Accounting Standards Update (ASU) No.&nbsp;2009-13, &#x201C;Revenue Arrangements with Multiple Deliverables&#x201D; on July&nbsp;1, 2010, the Company determined that its licenses lacked stand-alone value and were combined with other elements of the arrangement and any amounts associated with the license were deferred and amortized over a certain period, which the Company refers to as the Company&#x2019;s period of substantial involvement. The determination of the length of the period over which to defer revenue is subject to judgment and estimation and can have an impact on the amount of revenue recognized in a given period. Historically the Company&#x2019;s involvement with the development of a collaborator&#x2019;s product candidate has been significant at the early stages of development, and lessens as it progresses into clinical trials. Also, as a drug candidate gets closer to commencing pivotal testing the Company&#x2019;s collaborators have sought an alternative site to manufacture their products, as the Company&#x2019;s facility does not produce pivotal or commercial drug product. Accordingly, the Company generally estimates this period of substantial involvement to begin at the inception of the collaboration agreement and conclude at the end of non-pivotal Phase&nbsp;II testing. The Company believes this period of substantial involvement is, depending on the nature of the license, on average six and one-half years. Quarterly, the Company reassesses its periods of substantial involvement over which the Company amortizes its upfront license fees and makes adjustments as appropriate. In the event a collaborator elects to discontinue development of a specific product candidate under a development and commercialization license, but retains its right to use the Company&#x2019;s technology to develop an alternative product candidate to the same target or a target substitute, the Company would cease amortization of any remaining portion of the upfront fee until there is substantial preclinical activity on another product candidate and its remaining period of substantial involvement can be estimated. In the event that a development and commercialization license were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Subsequent to the adoption of ASU No.&nbsp;2009-13, the Company determined that its research licenses lack stand-alone value and are considered for aggregation with the other elements of the arrangement and accounted for as one unit of accounting.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Upfront payments on development and commercialization licenses may be recognized upon delivery of the license if facts and circumstances dictate that the license has stand-alone value from the undelivered elements, which generally include rights to future technological improvements, research services, delivery of cytotoxic agents and the manufacture of preclinical and clinical materials.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company recognizes revenue related to research services that represent separate units of accounting as they are performed, as long as there is persuasive evidence of an arrangement, the fee is fixed or determinable, and collection of the related receivable is probable. The Company recognizes revenue related to the rights to future technological improvements over the estimated term of the applicable license.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company may also provide cytotoxic agents to its collaborators or produce preclinical and clinical materials at negotiated prices which are generally consistent with what other third parties would charge. The Company recognizes revenue on cytotoxic agents and on preclinical and clinical materials when the materials have passed all quality testing required for collaborator acceptance and title and risk of loss have transferred to the collaborator. Arrangement consideration allocated to the manufacture of preclinical and clinical materials in a multiple-deliverable arrangement is below the Company&#x2019;s full cost, and the Company&#x2019;s full cost is not expected to ever be below its contract selling prices for its existing collaborations. During the three months ended September&nbsp;30, 2015 and 2014, the difference between the Company&#x2019;s full cost to manufacture preclinical and clinical materials on behalf of its collaborators as compared to total amounts received from collaborators for the manufacture of preclinical and clinical materials was $7.0 million and $3.1 million, respectively. The majority of the Company&#x2019;s costs to produce these preclinical and clinical materials are fixed and then allocated to each batch based on the number of batches produced during the period. Therefore, the Company&#x2019;s costs to produce these materials are significantly impacted by the number of batches produced during the period. The volume of preclinical and clinical materials the Company produces is directly related to the number of clinical trials the Company and its collaborators are preparing for or currently have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period such trials last. Accordingly, the volume of preclinical and clinical materials produced, and therefore the Company&#x2019;s per-batch costs to manufacture these preclinical and clinical materials, may vary significantly from period to period.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company may also produce research material for potential collaborators under material transfer agreements. Additionally, the Company performs research activities, including developing antibody specific conjugation processes, on behalf of its collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The Company records amounts received for research materials produced or services performed as a component of research and development support revenue. The Company also develops conjugation processes for materials for later-stage testing and commercialization for certain collaborators. The Company is compensated at negotiated rates and may receive milestone payments for developing these processes which are recorded as a component of research and development support revenue.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s development and commercialization license agreements have milestone payments which for reporting purposes are aggregated into three categories: (i)&nbsp;development milestones, (ii)&nbsp;regulatory milestones, and (iii)&nbsp;sales milestones. Development milestones are typically payable when a product candidate initiates or advances into different clinical trial phases. Regulatory milestones are typically payable upon submission for marketing approval with the U.S. Food and Drug Administration, or FDA, or other countries&#x2019; regulatory authorities or on receipt of actual marketing approvals for the compound or for additional indications. Sales milestones are typically payable when annual sales reach certain levels.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">At the inception of each agreement that includes milestone payments, the Company evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a)&nbsp;the consideration is commensurate with either (1)&nbsp;the entity&#x2019;s performance to achieve the milestone, or (2)&nbsp;the enhancement of the value of the delivered item(s)&nbsp;as a result of a specific outcome resulting from the entity&#x2019;s performance to achieve the milestone, (b)&nbsp;the consideration relates solely to past performance and (c)&nbsp;the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. The Company evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Non-refundable development and regulatory milestones that are expected to be achieved as a result of the Company&#x2019;s efforts during the period of substantial involvement are considered substantive and are recognized as revenue upon the achievement of the milestone, assuming all other revenue recognition criteria are met. Milestones that are not considered substantive because the Company does not contribute effort to the achievement of such milestones are generally achieved after the period of substantial involvement and are recognized as revenue upon achievement of the milestone, as there are no undelivered elements remaining and no continuing performance obligations, assuming all other revenue recognition criteria are met.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Under the Company&#x2019;s development and commercialization license agreements, the Company receives royalty payments based upon its licensees&#x2019; net sales of covered products. Generally, under these agreements the Company is to receive royalty reports and payments from its licensees approximately one quarter in arrears, that is, generally in the third month of the quarter after the licensee has sold the royalty-bearing product or products. The Company recognizes royalty revenues when it can reliably estimate such amounts and collectability is reasonably assured. As such, the Company generally recognizes royalty revenues in the quarter reported to the Company by its licensees, or one quarter following the quarter in which sales by the Company&#x2019;s licensees occurred.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt 0pt 0pt 54pt;text-indent: -18pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;text-decoration:underline;">Right-to-Test Agreements</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company&#x2019;s right-to-test agreements provide collaborators the right to (a)&nbsp;test the Company&#x2019;s ADC technology for a defined period of time through a research, or right-to-test, license, (b)&nbsp;take options, for a defined period of time, to specified targets and (c)&nbsp;upon exercise of those options, secure or &#x201C;take&#x201D; licenses to develop and commercialize products for the specified targets on established terms. Under these agreements, fees may be due to the Company (i)&nbsp;at the inception of the arrangement (referred to as &#x201C;upfront&#x201D; fees or payments), (ii)&nbsp;upon taking an option with respect to a specific target (referred to as option fees or payments earned, if any, when the option is &#x201C;taken&#x201D;), (iii)&nbsp;upon the exercise of a previously taken option to acquire a development and commercialization license(s)&nbsp;(referred to as exercise fees or payments earned, if any, when the development and commercialization license is &#x201C;taken&#x201D;), or (iv)&nbsp;some combination of all of these fees.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The accounting for right-to-test agreements is dependent on the nature of the options granted to the collaborative partner. Options are considered substantive if, at the inception of a right-to-test agreement, the Company is at risk as to whether the collaborative partner will choose to exercise the options to secure development and commercialization licenses. Factors that are considered in evaluating whether options are substantive include the overall objective of the arrangement, the benefit the collaborator might obtain from the agreement without exercising the options, the cost to exercise the options relative to the total upfront consideration, and the additional financial commitments or economic penalties imposed on the collaborator as a result of exercising the options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">For right-to-test agreements where the options to secure development and commercialization licenses to the Company&#x2019;s ADC technology are considered substantive, the Company does not consider the development and commercialization licenses to be a deliverable at the inception of the agreement. For those right-to-test agreements entered into prior to the adoption of ASU No.&nbsp;2009-13 where the options to secure development and commercialization licenses are considered substantive, the Company has deferred the upfront payments received and recognizes this revenue over the period during which the collaborator could elect to take options for development and commercialization licenses. These periods are specific to each collaboration agreement. If a collaborator takes an option to acquire a development and commercialization license under these agreements, any substantive option fee is deferred and recognized over the life of the option, generally 12 to 18&nbsp;months. If a collaborator exercises an option and takes a development and commercialization license to a specific target, the Company attributes the exercise fee to the development and commercialization license. Upon exercise of an option to acquire a development and commercialization license, the Company would also attribute any remaining deferred option fee to the development and commercialization license and apply the multiple-element revenue recognition criteria to the development and commercialization license and any other deliverables to determine the appropriate revenue recognition, which will be consistent with the Company&#x2019;s accounting policy for upfront payments on single-target licenses. In the event a right-to-test agreement were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination. None of the Company&#x2019;s right-to-test agreements entered into subsequent to the adoption of ASU No.&nbsp;2009-13 has been determined to contain substantive options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">For right-to-test agreements where the options to secure development and commercialization licenses to the Company&#x2019;s ADC technology are not considered substantive, the Company considers the development and commercialization licenses to be a deliverable at the inception of the agreement and applies the multiple-element revenue recognition criteria to determine the appropriate revenue recognition. None of the Company&#x2019;s right-to-test agreements entered into prior to the adoption of ASU No.&nbsp;2009-13 has been determined to contain non-substantive options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company does not directly control when or if any collaborator will exercise its options for development and commercialization licenses. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 13203000 14851000 4166000 235000000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:28.12%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:67.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Options outstanding to purchase common stock and unvested restricted stock (in thousands)</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11,494&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>10,564&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:03.12%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.26%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:67.50%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Common stock equivalents under treasury stock method</font></p> </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,296&nbsp; </td> <td valign="bottom" style="width:03.12%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:12.50%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,147&nbsp; </td> <td valign="bottom" style="width:01.26%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The minimum rental commitments for the Company&#x2019;s facilities, including real estate taxes and other expenses, for the next five fiscal years and thereafter under the non-cancelable operating lease agreements discussed above are as follows (in&nbsp;thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2016&nbsp;(nine months&nbsp;remaining)</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>5,519 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2017</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,147 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2018</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>7,253 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2019</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,441 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">2020</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6,423 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Thereafter</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>38,857 </td> <td valign="bottom" style="width:01.16%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum lease payments</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>71,640 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:84.42%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum rental payments from sublease</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:11.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>(340 </td> <td valign="bottom" style="width:01.16%;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">)</font></p> </td> </tr> <tr> <td valign="top" style="width:84.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total minimum lease payments, net</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:10.24%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>71,300 </td> <td valign="bottom" style="width:01.16%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Inventory at September&nbsp;30, 2015 and June&nbsp;30, 2015 is summarized below (in thousands):</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:65.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">June&nbsp;30,</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.36%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Raw materials</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>76&nbsp; </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>279&nbsp; </td> <td valign="bottom" style="width:01.14%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.36%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Work in process</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,170&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,656&nbsp; </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:02.88%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="2" valign="bottom" style="width:13.86%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.14%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:65.36%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Total</font></p> </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1,246&nbsp; </td> <td valign="bottom" style="width:02.88%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:01.30%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">$</font></p> </td> <td valign="bottom" style="width:12.56%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:2pt double #000000 ;border-right:1pt none #D9D9D9 ;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>2,935&nbsp; </td> <td valign="bottom" style="width:01.14%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:64.34%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.04%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.34%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Collaborative&nbsp;Partner:</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.44%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.34%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Biotest</font></p> </td> <td valign="bottom" style="width:03.18%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>16&nbsp; </td> <td valign="bottom" style="width:03.20%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.44%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11&nbsp; </td> <td valign="bottom" style="width:02.44%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.34%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Lilly</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>35&nbsp; </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.44%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3&nbsp; </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.34%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi</font></p> </td> <td valign="bottom" style="width:03.18%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:03.20%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.44%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>45&nbsp; </td> <td valign="bottom" style="width:02.44%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.34%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Roche</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>38&nbsp; </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.44%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>32&nbsp; </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 100.00%;margin-left:0pt;"> <tr> <td valign="bottom" style="width:64.34%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.04%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.34%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.44%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.34%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Dividend</font></p> </td> <td valign="bottom" style="width:03.18%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:03.20%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.44%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:02.44%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.34%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Volatility</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>67.07&nbsp; </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.44%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>60.44&nbsp; </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.34%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Risk-free interest rate</font></p> </td> <td valign="bottom" style="width:03.18%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.89&nbsp; </td> <td valign="bottom" style="width:03.20%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.44%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.88&nbsp; </td> <td valign="bottom" style="width:02.44%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.34%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Expected life (years)</font></p> </td> <td valign="bottom" style="width:03.18%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.42%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:03.20%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.44%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:02.44%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Segment Information</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, the Company continued to operate in one operating segment which is the business of discovery of monoclonal antibody-based anticancer therapeutics.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The percentages of revenues recognized from significant customers of the Company in the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and 2014 are included in the following table:</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;"> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.54%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Collaborative&nbsp;Partner:</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Biotest</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>16&nbsp; </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>11&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Lilly</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>35&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>3&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Sanofi</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&#x2014;</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>45&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Roche</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>38&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>32&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">There were no other customers of the Company with significant revenues in the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015 </font><font style="display:inline;font-size:10pt;">and 2014.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 5410000 -8000 5783000 -30000 P1Y P1Y P4Y 0.00 0.00 P6Y3M18D P6Y3M18D 0.6044 0.6707 0.0188 0.0189 5500000 17500000 80000 80000 1676599 6.27 10.31 0 17.00 3.19 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Stock-Based Compensation</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">As of September&nbsp;30, 2015, the Company is authorized to grant future awards under one employee share-based compensation plan, which is the ImmunoGen,&nbsp;Inc. 2006 Employee, Director and Consultant Equity Incentive Plan, or the 2006 Plan. At the annual meeting of shareholders on November&nbsp;11, 2014, an amendment to the 2006 Plan was approved and an additional 5,500,000 shares were authorized for issuance under this plan.&nbsp;&nbsp;As amended, the 2006 Plan provides for the issuance of Stock Grants, the grant of Options and the grant of Stock-Based Awards for up to 17,500,000 shares of the Company&#x2019;s common stock, as well as 1,676,599 shares of common stock which represent awards granted under the previous stock option plan, the ImmunoGen,&nbsp;Inc. Restated Stock Option Plan, or the Former Plan, that were forfeited, expired or were cancelled without delivery of shares of common stock or which resulted in the forfeiture of shares of common stock back to the Company between November&nbsp;11, 2006 and June&nbsp;30, 2014. Option awards are granted with an exercise price equal to the market price of the Company&#x2019;s stock at the date of grant. Options vest at various periods of up to four years and may be exercised within ten years of the date of grant.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The stock-based awards are accounted for under ASC Topic 718, &#x201C;Compensation&#x2014;Stock Compensation.&#x201D; Pursuant to Topic 718, the estimated grant date fair value of awards is charged to the statement of operations and comprehensive loss over the requisite service period, which is the vesting period. Such amounts have been reduced by an estimate of forfeitures of all unvested awards. The fair value of each stock option is estimated on the date of grant using the Black-Scholes option-pricing model with the assumptions noted in the following table. As the Company has not paid dividends since inception, nor does it expect to pay any dividends for the foreseeable future, the expected dividend yield assumption is zero. Expected volatility is based exclusively on historical volatility data of the Company&#x2019;s stock. The expected term of stock options granted is based exclusively on historical data and represents the period of time that stock options granted are expected to be outstanding. The expected term is calculated for and applied to one group of stock options as the Company does not expect substantially different exercise or post-vesting termination behavior among its option recipients. The risk-free rate of the stock options is based on the U.S. Treasury rate in effect at the time of grant for the expected term of the stock options.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <div style="width:100%;"><table cellpadding="0" cellspacing="0" style="border-collapse:collapse;width: 73.00%;margin-left:72pt;"> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td colspan="3" valign="bottom" style="width:30.68%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">Three&nbsp;Months&nbsp;Ended</font><br /><font style="display:inline;font-weight:bold;font-size:8pt;">September&nbsp;30,</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="bottom" style="width:64.54%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-size:8pt;">&nbsp;</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2015</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;border-top:1pt none #D9D9D9 ;border-left:1pt none #D9D9D9 ;border-bottom:1pt solid #000000 ;border-right:1pt none #D9D9D9 ;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 8pt;"> <font style="display:inline;font-weight:bold;font-size:8pt;">2014</font></p> </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:center;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Dividend</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;text-align:right;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">None</font></p> </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Volatility</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>67.07&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>60.44&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Risk-free interest rate</font></p> </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.89&nbsp; </td> <td valign="bottom" style="width:03.40%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> <td valign="bottom" style="width:13.64%;background-color: #CCEEFF;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>1.88&nbsp; </td> <td valign="bottom" style="width:01.36%;background-color: #CCEEFF;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">%</font></p> </td> </tr> <tr> <td valign="top" style="width:64.54%;padding:0pt;"> <p style="margin:0pt 0pt 0pt 10.1pt;line-height:106.67%;text-indent: -10.1pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Expected life (years)</font></p> </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:03.40%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> <td valign="bottom" style="width:13.64%;;font-family:Times New Roman;font-size:10pt;text-align:right;" nowrap="nowrap"><div style="float:left"></div>6.3&nbsp; </td> <td valign="bottom" style="width:01.36%;padding:0pt;"> <p style="margin:0pt;line-height:106.67%;font-family:Times New Roman;font-size: 12pt;"> &nbsp;</p> </td> </tr> </table></div> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Using the Black-Scholes option-pricing model, the weighted average grant date fair values of options granted during the three months ended September&nbsp;30, 2015 and 2014 were $10.31 and $6.27 per share, respectively.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">Stock compensation expense related to stock options and restricted stock awards granted under the 2006 Plan was $5.7 million and $5.3 million during the three months ended September&nbsp;30, 2015 and 2014, respectively. As of September&nbsp;30, 2015, the estimated fair value of unvested employee awards was $35 million, net of estimated forfeitures. The weighted-average remaining vesting period for these awards is approximately two and a half years.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, holders of options issued under the Company&#x2019;s equity plans exercised their rights to acquire an aggregate of approximately 402,000 shares of common stock at prices ranging from $3.19 to $17.00 per share.&nbsp; The total proceeds to the Company from these option exercises were approximately $4.5 million.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-weight:bold;font-size:10pt;">D.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;Capital Stock</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">2001 Non-Employee Director Stock Plan</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">, the Company recorded approximately ($30,000) in expense reduction, respectively, related to stock units outstanding under the Company&#x2019;s 2001 Non-Employee Director Stock Plan, or the 2001 Plan, compared to ($8,000) in expense reduction recorded during the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2014</font><font style="display:inline;font-size:10pt;">. The value of the stock units are classified as a liability and adjusted to market value at each reporting period as the redemption amount of stock units for this plan will be paid in cash.&nbsp;&nbsp;No stock units have been issued under the 2001 Plan subsequent to June&nbsp;30, 2004.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Compensation Policy for Non-Employee Directors</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">On November&nbsp;12, 2013, the Board amended the Compensation Policy for Non-Employee Directors to make certain changes to the compensation of its non-employee directors, including an increase in the fees paid in cash to the non-employee directors. Under the terms of the amended policy</font><font style="display:inline;font-size:10pt;">, the redemption amount of deferred share units issued will continue to be paid in shares of common stock of the Company on the date a director ceases to be a member of the Board. Annual retainers vest quarterly over approximately one year from the date of grant, contingent upon the individual remaining a director of ImmunoGen as of each vesting date.&nbsp;&nbsp;The number of deferred share units awarded is now fixed per the plan on the date of the award and is no longer based on the market price of the Company&#x2019;s common stock on the date of the award. All unvested deferred stock awards will automatically vest immediately prior to the occurrence of a change of control.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">In addition to the deferred share units, the Non-Employee Directors are also entitled to receive a fixed number of stock options determined using the Black-Scholes option pricing model measured on the date of grant, which would be the date of the annual meeting of shareholders.&nbsp;&nbsp;These options vest quarterly over approximately one year from the date of grant.&nbsp;&nbsp;Any new directors will receive a pro-rated award, depending on their date of election to the Board.&nbsp;&nbsp;The directors received a total of 80,000 stock options in each fiscal year 2015 and 2014, and the related compensation expense for the three months ended September&nbsp;30, 2015 and 2014 is included in the amounts discussed in the &#x201C;Stock-Based Compensation&#x201D; section of footnote A above.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:39pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">During the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2015</font><font style="display:inline;font-size:10pt;">,</font><font style="display:inline;font-size:10pt;"> the Company recorded approximately $82,000 in compensation expense, respectively, related to deferred share units issued and outstanding under the Company&#x2019;s Compensation Policy for Non-Employee Directors, compared to $118,000 in compensation expense recorded during the three months ended </font><font style="display:inline;font-size:10pt;">September&nbsp;30, 2014</font><font style="display:inline;font-size:10pt;">.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> 35104000 11609000 402000 <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Subsequent Events</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The Company has evaluated all events or transactions that occurred after September&nbsp;30, 2015 up through the date the Company issued these financial statements. </font><font style="display:inline;font-size:10pt;">In October&nbsp;2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. </font><font style="display:inline;font-size:10pt;">The Company did not have any other material recognizable or unrecognizable subsequent events during this period.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> </font></p></div><div style="margin-left:0%;margin-right:0%;"></div> </div> <div> <div style="margin-left:0%;margin-right:0%;"></div><div style="margin-left:0%;margin-right:0%;"> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-style:italic;font-size:10pt;">Unbilled Revenue</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;text-indent:36pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">The majority of the Company&#x2019;s unbilled revenue at September&nbsp;30, 2015 and June&nbsp;30, 2015 represents research funding earned prior to those dates based on actual resources utilized under the Company&#x2019;s agreements with various collaborators.</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p> <p style="margin:0pt;font-family:Times New Roman;font-size: 10pt;"> <font style="display:inline;font-size:10pt;">&nbsp;</font> </p></div><div style="margin-left:0%;margin-right:0%;"> <p><font size="1"> 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Commitments and Contingencies (Details)
1 Months Ended 3 Months Ended
Apr. 30, 2014
USD ($)
item
Apr. 30, 2013
ft²
Sep. 30, 2015
USD ($)
Dec. 31, 2013
USD ($)
ft²
Jul. 27, 2007
ft²
Minimum rental commitments under the non-cancelable operating lease agreements          
2016 (nine months remaining)     $ 5,519,000    
2017     7,147,000    
2018     7,253,000    
2019     6,441,000    
2020     6,423,000    
Thereafter     38,857,000    
Total minimum lease payments     71,640,000    
Total minimum rental payments from sublease     (340,000)    
Total minimum lease payments, net     71,300,000    
Obligations under capital leases     0    
Collaborations          
Potential milestone payable     162,000,000    
Amount reimbursable by a third party     $ 1,400,000    
830 Winter Street, Waltham, MA          
Operating leases          
Area of space leased (in square feet) | ft²         89,000
Additional area of space leased (in square feet) | ft²       19,000  
Construction allowance receivable $ 1,100,000     $ 746,000  
Number of additional terms for which lease agreement can be extended | item 2        
Additional term period for which lease agreement can be extended 5 years        
333 Providence Hwy, Norwood MA          
Operating leases          
Additional term period for which lease agreement can be extended     5 years    
100 River Ridge Drive, Norwood, MA          
Operating leases          
Area of space leased (in square feet) | ft²   7,507      
Initial lease term period   5 years 2 months      
Additional term period for which lease agreement can be extended   5 years      
XML 14 R9.htm IDEA: XBRL DOCUMENT v3.3.0.814
Capital Stock
3 Months Ended
Sep. 30, 2015
Capital Stock  
Capital Stock

D.     Capital Stock

 

2001 Non-Employee Director Stock Plan

 

During the three months ended September 30, 2015, the Company recorded approximately ($30,000) in expense reduction, respectively, related to stock units outstanding under the Company’s 2001 Non-Employee Director Stock Plan, or the 2001 Plan, compared to ($8,000) in expense reduction recorded during the three months ended September 30, 2014. The value of the stock units are classified as a liability and adjusted to market value at each reporting period as the redemption amount of stock units for this plan will be paid in cash.  No stock units have been issued under the 2001 Plan subsequent to June 30, 2004.

 

Compensation Policy for Non-Employee Directors

 

On November 12, 2013, the Board amended the Compensation Policy for Non-Employee Directors to make certain changes to the compensation of its non-employee directors, including an increase in the fees paid in cash to the non-employee directors. Under the terms of the amended policy, the redemption amount of deferred share units issued will continue to be paid in shares of common stock of the Company on the date a director ceases to be a member of the Board. Annual retainers vest quarterly over approximately one year from the date of grant, contingent upon the individual remaining a director of ImmunoGen as of each vesting date.  The number of deferred share units awarded is now fixed per the plan on the date of the award and is no longer based on the market price of the Company’s common stock on the date of the award. All unvested deferred stock awards will automatically vest immediately prior to the occurrence of a change of control.

 

In addition to the deferred share units, the Non-Employee Directors are also entitled to receive a fixed number of stock options determined using the Black-Scholes option pricing model measured on the date of grant, which would be the date of the annual meeting of shareholders.  These options vest quarterly over approximately one year from the date of grant.  Any new directors will receive a pro-rated award, depending on their date of election to the Board.  The directors received a total of 80,000 stock options in each fiscal year 2015 and 2014, and the related compensation expense for the three months ended September 30, 2015 and 2014 is included in the amounts discussed in the “Stock-Based Compensation” section of footnote A above.

 

During the three months ended September 30, 2015, the Company recorded approximately $82,000 in compensation expense, respectively, related to deferred share units issued and outstanding under the Company’s Compensation Policy for Non-Employee Directors, compared to $118,000 in compensation expense recorded during the three months ended September 30, 2014.

 

XML 15 R8.htm IDEA: XBRL DOCUMENT v3.3.0.814
Liability Related to Sale of Future Royalties
3 Months Ended
Sep. 30, 2015
Liabilities Related to Sale of Future Royalties  
Liability Related To Sale of Future Royalties

C.    Liability Related to Sale of Future Royalties

 

In April 2015, Immunity Royalty Holdings, L.P. (IRH) purchased the right to receive 100% of the royalty payments on commercial sales of Kadcyla arising under the Company’s development and commercialization license with Genentech, until IRH has received aggregate royalties equal to $235 million or $260 million, depending on when the aggregate royalties received by IRH reach a specified milestone.  Once the applicable threshold is met, if ever, the Company will thereafter receive 85% and IRH will receive 15% of the Kadcyla royalties for the remaining royalty term.  At consummation of the transaction in April 2015, the Company received cash proceeds of $200 million.  As part of this sale, the Company incurred $5.9 million of transaction costs, which are presented in the accompanying consolidated balance sheet as deferred financing costs and will be amortized to interest expense over the estimated life of the royalty purchase agreement.  Although the Company sold its rights to receive royalties from the sales of Kadcyla, as a result of its ongoing involvement in the cash flows related to these royalties, the Company will continue to account for these royalties as revenue and recorded the $200 million in proceeds from this transaction as a liability related to sale of future royalties (Royalty Obligation) that will be amortized using the interest method over the estimated life of the royalty purchase agreement.

 

The following table shows the activity within the liability account during the three-month period ended September 30, 2015 (in thousands):

 

 

 

Period from
June 30, 2015 to
September 30,
2015

 

Liability related to sale of future royalties — beginning balance

 

$

199,662

 

Non-cash Kadcyla royalty revenue

 

(5,684

)

Non-cash interest expense recognized

 

4,851

 

 

 

 

 

Liability related to sale of future royalties — ending balance

 

$

198,829

 

 

As royalties are remitted to IRH, the balance of the Royalty Obligation will be effectively repaid over the life of the agreement.  In order to determine the amortization of the Royalty Obligation, the Company is required to estimate the total amount of future royalty payments to be received and remitted to IRH as noted above over the life of the agreement. The sum of these amounts less the $200 million proceeds the Company received will be recorded as interest expense over the life of the Royalty Obligation. Since inception, the Company’s estimate of this total interest expense resulted in an effective annual interest rate of 9.8%. The Company periodically assesses the estimated royalty payments to IRH and to the extent such payments are greater or less than its initial estimates, or the timing of such payments is materially different than its original estimates, the Company will prospectively adjust the amortization of the Royalty Obligation. There are a number of factors that could materially affect the amount and timing of royalty payments from Genentech, most of which are not within the Company’s control. Such factors include, but are not limited to, changing standards of care, the introduction of competing products, manufacturing or other delays, biosimilar competition, patent protection, adverse events that result in governmental health authority imposed restrictions on the use of the drug products, significant changes in foreign exchange rates as the royalties remitted to IRH are made in U.S. dollars (USD) while significant portions of the underlying sales of Kadcyla are made in currencies other than USD, and other events or circumstances that could result in reduced royalty payments from Kadcyla, all of which would result in a reduction of non-cash royalty revenues and the non-cash interest expense over the life of the Royalty Obligation. Conversely, if sales of Kadcyla are more than expected, the non-cash royalty revenues and the non-cash interest expense recorded by the Company would be greater over the term of the Royalty Obligation.

 

In addition, the royalty purchase agreement grants IRH the right to receive certain reports and other information relating to the royalties and contains other representations and warranties, covenants and indemnification obligations that are customary for a transaction of this nature.

 

XML 16 R2.htm IDEA: XBRL DOCUMENT v3.3.0.814
CONSOLIDATED BALANCE SHEETS - USD ($)
$ in Thousands
Sep. 30, 2015
Jun. 30, 2015
ASSETS    
Cash and cash equivalents $ 247,843 $ 278,109
Accounts receivable 6,812 5,088
Unbilled revenue 899 714
Inventory 1,246 2,935
Current portion of deferred financing costs 1,136 1,159
Prepaid and other current assets 4,080 4,175
Total current assets 262,016 292,180
Property and equipment, net of accumulated depreciation 18,510 16,254
Deferred financing costs, net of current portion 4,147 4,415
Other assets 911 974
Total assets 285,584 313,823
LIABILITIES AND SHAREHOLDERS' EQUITY    
Accounts payable 9,689 8,138
Accrued compensation 3,262 8,346
Other accrued liabilities 9,631 10,441
Current portion of deferred lease incentive 646 646
Current portion of liability related to the sale of future royalties 11,862 7,906
Current portion of deferred revenue 858 333
Total current liabilities 35,948 35,810
Deferred lease incentive, net of current portion 6,139 6,301
Deferred revenue, net of current portion 40,794 40,855
Liability related to the sale of future royalties, net of current portion 186,967 191,756
Other long-term liabilities 4,127 3,997
Total liabilities $ 273,975 $ 278,719
Commitments and contingencies (Note E)
Shareholders' equity:    
Preferred stock, $0.01 par value; authorized 5,000 shares; no shares issued and outstanding
Common stock, $0.01 par value; authorized 150,000 shares; issued and outstanding 86,981 and 86,579 shares as of September 30, 2015 and June 30, 2015, respectively $ 870 $ 866
Additional paid-in capital 753,349 743,108
Accumulated deficit (742,610) (708,870)
Total shareholders' equity 11,609 35,104
Total liabilities and shareholders' equity $ 285,584 $ 313,823
XML 17 R6.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies
3 Months Ended
Sep. 30, 2015
Summary of Significant Accounting Policies  
Summary of Significant Accounting Policies

A.Summary of Significant Accounting Policies

 

Basis of Presentation

 

The accompanying unaudited consolidated financial statements at September 30, 2015 and June 30, 2015 and for the three months ended September 30, 2015 and 2014 include the accounts of ImmunoGen, Inc., or the Company, and its wholly owned subsidiaries, ImmunoGen Securities Corp., ImmunoGen Europe Limited and Hurricane, LLC. The consolidated financial statements include all of the adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation of the Company’s financial position in accordance with accounting principles generally accepted in the U.S. for interim financial information. The June 30, 2015 condensed consolidated balance sheet data presented for comparative purposes was derived from our audited financial statements but certain information and footnote disclosures normally included in the Company’s annual financial statements have been condensed or omitted. The preparation of interim financial statements requires the use of management’s estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim financial statements and the reported amounts of revenues and expenditures during the reported periods. The results of the interim periods are not necessarily indicative of the results for the entire year. Accordingly, the interim financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended June 30, 2015.

 

Subsequent Events

 

The Company has evaluated all events or transactions that occurred after September 30, 2015 up through the date the Company issued these financial statements. In October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The Company did not have any other material recognizable or unrecognizable subsequent events during this period.

 

Revenue Recognition

 

The Company enters into licensing and development agreements with collaborative partners for the development of monoclonal antibody-based anticancer therapeutics. The terms of these agreements contain multiple deliverables which may include (i) licenses, or options to obtain licenses, to the Company’s antibody-drug conjugate, or ADC, technology, (ii) rights to future technological improvements, (iii) research activities to be performed on behalf of the collaborative partner, (iv) delivery of cytotoxic agents and (v) the manufacture of preclinical or clinical materials for the collaborative partner. Payments to the Company under these agreements may include upfront fees, option fees, exercise fees, payments for research activities, payments for the manufacture of preclinical or clinical materials, payments based upon the achievement of certain milestones and royalties on product sales. The Company follows the provisions of the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 605-25, “Revenue Recognition—Multiple-Element Arrangements,” and ASC Topic 605-28, “Revenue Recognition-Milestone Method,” in accounting for these agreements. In order to account for these agreements, the Company must identify the deliverables included within the agreement and evaluate which deliverables represent separate units of accounting based on if certain criteria are met, including whether the delivered element has stand-alone value to the collaborator. The consideration received is allocated among the separate units of accounting, and the applicable revenue recognition criteria are applied to each of the separate units.

 

At September 30, 2015, the Company had the following two types of agreements with the parties identified below:

 

·

Development and commercialization licenses, which provide the party with the right to use the Company’s ADC technology and/or certain other intellectual property to develop compounds to a specified antigen target:

 

Amgen (four exclusive single-target licenses(1))

 

Bayer HealthCare (one exclusive single-target license)

 

Biotest (one exclusive single-target license)

 

Lilly (three exclusive single-target licenses)

 

 

(1)

Amgen has sublicensed one of its exclusive single-target licenses to Oxford BioTherapeutics Ltd.

 

 

 

 

Novartis (five exclusive single-target licenses and one license to two related targets: one target on an exclusive basis and the second target on a non-exclusive basis)

 

Roche, through its Genentech unit (five exclusive single-target licenses)

 

Sanofi (one exclusive single-target license and one exclusive license to multiple individual targets)

 

·

Research license/option agreement for a defined period of time to secure development and commercialization licenses to use the Company’s ADC technology to develop anticancer compounds to specified targets on established terms (referred to herein as right-to-test agreements):

 

Sanofi

 

CytomX

 

Takeda, through its wholly owned subsidiary, Millennium Pharmaceuticals, Inc.

 

There are no performance, cancellation, termination or refund provisions in any of the arrangements that contain material financial consequences to the Company.

 

Development and Commercialization Licenses

 

The deliverables under a development and commercialization license agreement generally include the license to the Company’s ADC technology with respect to a specified antigen target, and may also include deliverables related to rights to future technological improvements, research activities to be performed on behalf of the collaborative partner and the manufacture of preclinical or clinical materials for the collaborative partner.

 

Generally, development and commercialization licenses contain non-refundable terms for payments and, depending on the terms of the agreement, provide that the Company will (i) at the collaborator’s request, provide research services at negotiated prices which are generally consistent with what other third parties would charge, (ii) at the collaborator’s request, manufacture and provide to it preclinical and clinical materials or deliver cytotoxic agents at negotiated prices which are generally consistent with what other third parties would charge, (iii) earn payments upon the achievement of certain milestones and (iv) earn royalty payments, generally until the later of the last applicable patent expiration or 10 to 12 years after product launch. In the case of Kadcyla, however, the minimum royalty term is 10 years and the maximum royalty term is 12 years on a country by country basis, regardless of patent protection.  Royalty rates may vary over the royalty term depending on the Company’s intellectual property rights and/or the presence of comparable competing products. The Company may provide technical assistance and share any technology improvements with its collaborators during the term of the collaboration agreements. The Company does not directly control when or whether any collaborator will request research or manufacturing services, achieve milestones or become liable for royalty payments. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

In determining the units of accounting, management evaluates whether the license has stand-alone value from the undelivered elements to the collaborative partner based on the consideration of the relevant facts and circumstances for each arrangement. Factors considered in this determination include the research capabilities of the partner and the availability of ADC technology research expertise in the general marketplace. If the Company concludes that the license has stand-alone value and therefore will be accounted for as a separate unit of accounting, the Company then determines the estimated selling prices of the license and all other units of accounting based on market conditions, similar arrangements entered into by third parties, and entity-specific factors such as the terms of the Company’s previous collaborative agreements, recent preclinical and clinical testing results of therapeutic products that use the Company’s ADC technology, the Company’s pricing practices and pricing objectives, the likelihood that technological improvements will be made, and, if made, will be used by the Company’s collaborators and the nature of the research services to be performed on behalf of its collaborators and market rates for similar services.

 

Upfront payments on development and commercialization licenses are deferred if facts and circumstances dictate that the license does not have stand-alone value. Prior to the adoption of Accounting Standards Update (ASU) No. 2009-13, “Revenue Arrangements with Multiple Deliverables” on July 1, 2010, the Company determined that its licenses lacked stand-alone value and were combined with other elements of the arrangement and any amounts associated with the license were deferred and amortized over a certain period, which the Company refers to as the Company’s period of substantial involvement. The determination of the length of the period over which to defer revenue is subject to judgment and estimation and can have an impact on the amount of revenue recognized in a given period. Historically the Company’s involvement with the development of a collaborator’s product candidate has been significant at the early stages of development, and lessens as it progresses into clinical trials. Also, as a drug candidate gets closer to commencing pivotal testing the Company’s collaborators have sought an alternative site to manufacture their products, as the Company’s facility does not produce pivotal or commercial drug product. Accordingly, the Company generally estimates this period of substantial involvement to begin at the inception of the collaboration agreement and conclude at the end of non-pivotal Phase II testing. The Company believes this period of substantial involvement is, depending on the nature of the license, on average six and one-half years. Quarterly, the Company reassesses its periods of substantial involvement over which the Company amortizes its upfront license fees and makes adjustments as appropriate. In the event a collaborator elects to discontinue development of a specific product candidate under a development and commercialization license, but retains its right to use the Company’s technology to develop an alternative product candidate to the same target or a target substitute, the Company would cease amortization of any remaining portion of the upfront fee until there is substantial preclinical activity on another product candidate and its remaining period of substantial involvement can be estimated. In the event that a development and commercialization license were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination.

 

Subsequent to the adoption of ASU No. 2009-13, the Company determined that its research licenses lack stand-alone value and are considered for aggregation with the other elements of the arrangement and accounted for as one unit of accounting.

 

Upfront payments on development and commercialization licenses may be recognized upon delivery of the license if facts and circumstances dictate that the license has stand-alone value from the undelivered elements, which generally include rights to future technological improvements, research services, delivery of cytotoxic agents and the manufacture of preclinical and clinical materials.

 

The Company recognizes revenue related to research services that represent separate units of accounting as they are performed, as long as there is persuasive evidence of an arrangement, the fee is fixed or determinable, and collection of the related receivable is probable. The Company recognizes revenue related to the rights to future technological improvements over the estimated term of the applicable license.

 

The Company may also provide cytotoxic agents to its collaborators or produce preclinical and clinical materials at negotiated prices which are generally consistent with what other third parties would charge. The Company recognizes revenue on cytotoxic agents and on preclinical and clinical materials when the materials have passed all quality testing required for collaborator acceptance and title and risk of loss have transferred to the collaborator. Arrangement consideration allocated to the manufacture of preclinical and clinical materials in a multiple-deliverable arrangement is below the Company’s full cost, and the Company’s full cost is not expected to ever be below its contract selling prices for its existing collaborations. During the three months ended September 30, 2015 and 2014, the difference between the Company’s full cost to manufacture preclinical and clinical materials on behalf of its collaborators as compared to total amounts received from collaborators for the manufacture of preclinical and clinical materials was $7.0 million and $3.1 million, respectively. The majority of the Company’s costs to produce these preclinical and clinical materials are fixed and then allocated to each batch based on the number of batches produced during the period. Therefore, the Company’s costs to produce these materials are significantly impacted by the number of batches produced during the period. The volume of preclinical and clinical materials the Company produces is directly related to the number of clinical trials the Company and its collaborators are preparing for or currently have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period such trials last. Accordingly, the volume of preclinical and clinical materials produced, and therefore the Company’s per-batch costs to manufacture these preclinical and clinical materials, may vary significantly from period to period.

 

The Company may also produce research material for potential collaborators under material transfer agreements. Additionally, the Company performs research activities, including developing antibody specific conjugation processes, on behalf of its collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The Company records amounts received for research materials produced or services performed as a component of research and development support revenue. The Company also develops conjugation processes for materials for later-stage testing and commercialization for certain collaborators. The Company is compensated at negotiated rates and may receive milestone payments for developing these processes which are recorded as a component of research and development support revenue.

 

The Company’s development and commercialization license agreements have milestone payments which for reporting purposes are aggregated into three categories: (i) development milestones, (ii) regulatory milestones, and (iii) sales milestones. Development milestones are typically payable when a product candidate initiates or advances into different clinical trial phases. Regulatory milestones are typically payable upon submission for marketing approval with the U.S. Food and Drug Administration, or FDA, or other countries’ regulatory authorities or on receipt of actual marketing approvals for the compound or for additional indications. Sales milestones are typically payable when annual sales reach certain levels.

 

At the inception of each agreement that includes milestone payments, the Company evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a) the consideration is commensurate with either (1) the entity’s performance to achieve the milestone, or (2) the enhancement of the value of the delivered item(s) as a result of a specific outcome resulting from the entity’s performance to achieve the milestone, (b) the consideration relates solely to past performance and (c) the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. The Company evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment.

 

Non-refundable development and regulatory milestones that are expected to be achieved as a result of the Company’s efforts during the period of substantial involvement are considered substantive and are recognized as revenue upon the achievement of the milestone, assuming all other revenue recognition criteria are met. Milestones that are not considered substantive because the Company does not contribute effort to the achievement of such milestones are generally achieved after the period of substantial involvement and are recognized as revenue upon achievement of the milestone, as there are no undelivered elements remaining and no continuing performance obligations, assuming all other revenue recognition criteria are met.

 

Under the Company’s development and commercialization license agreements, the Company receives royalty payments based upon its licensees’ net sales of covered products. Generally, under these agreements the Company is to receive royalty reports and payments from its licensees approximately one quarter in arrears, that is, generally in the third month of the quarter after the licensee has sold the royalty-bearing product or products. The Company recognizes royalty revenues when it can reliably estimate such amounts and collectability is reasonably assured. As such, the Company generally recognizes royalty revenues in the quarter reported to the Company by its licensees, or one quarter following the quarter in which sales by the Company’s licensees occurred.

 

Right-to-Test Agreements

 

The Company’s right-to-test agreements provide collaborators the right to (a) test the Company’s ADC technology for a defined period of time through a research, or right-to-test, license, (b) take options, for a defined period of time, to specified targets and (c) upon exercise of those options, secure or “take” licenses to develop and commercialize products for the specified targets on established terms. Under these agreements, fees may be due to the Company (i) at the inception of the arrangement (referred to as “upfront” fees or payments), (ii) upon taking an option with respect to a specific target (referred to as option fees or payments earned, if any, when the option is “taken”), (iii) upon the exercise of a previously taken option to acquire a development and commercialization license(s) (referred to as exercise fees or payments earned, if any, when the development and commercialization license is “taken”), or (iv) some combination of all of these fees.

 

The accounting for right-to-test agreements is dependent on the nature of the options granted to the collaborative partner. Options are considered substantive if, at the inception of a right-to-test agreement, the Company is at risk as to whether the collaborative partner will choose to exercise the options to secure development and commercialization licenses. Factors that are considered in evaluating whether options are substantive include the overall objective of the arrangement, the benefit the collaborator might obtain from the agreement without exercising the options, the cost to exercise the options relative to the total upfront consideration, and the additional financial commitments or economic penalties imposed on the collaborator as a result of exercising the options.

 

For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are considered substantive, the Company does not consider the development and commercialization licenses to be a deliverable at the inception of the agreement. For those right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 where the options to secure development and commercialization licenses are considered substantive, the Company has deferred the upfront payments received and recognizes this revenue over the period during which the collaborator could elect to take options for development and commercialization licenses. These periods are specific to each collaboration agreement. If a collaborator takes an option to acquire a development and commercialization license under these agreements, any substantive option fee is deferred and recognized over the life of the option, generally 12 to 18 months. If a collaborator exercises an option and takes a development and commercialization license to a specific target, the Company attributes the exercise fee to the development and commercialization license. Upon exercise of an option to acquire a development and commercialization license, the Company would also attribute any remaining deferred option fee to the development and commercialization license and apply the multiple-element revenue recognition criteria to the development and commercialization license and any other deliverables to determine the appropriate revenue recognition, which will be consistent with the Company’s accounting policy for upfront payments on single-target licenses. In the event a right-to-test agreement were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination. None of the Company’s right-to-test agreements entered into subsequent to the adoption of ASU No. 2009-13 has been determined to contain substantive options.

 

For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are not considered substantive, the Company considers the development and commercialization licenses to be a deliverable at the inception of the agreement and applies the multiple-element revenue recognition criteria to determine the appropriate revenue recognition. None of the Company’s right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 has been determined to contain non-substantive options.

 

The Company does not directly control when or if any collaborator will exercise its options for development and commercialization licenses. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

Financial Instruments and Concentration of Credit Risk

 

Cash and cash equivalents are primarily maintained with three financial institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and, therefore, bear minimal risk. The Company’s cash equivalents consist of money market funds with underlying investments primarily being U.S. Government issued securities and high quality, short term commercial paper. Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash, cash equivalents and marketable securities. The Company held no marketable securities as of September 30, 2015 and June 30, 2015. The Company’s investment policy, approved by the Board of Directors, limits the amount it may invest in any one type of investment, thereby reducing credit risk concentrations.

 

Cash and Cash Equivalents

 

All highly liquid financial instruments with maturities of three months or less when purchased are considered cash equivalents. As of September 30, 2015 and June 30, 2015, the Company held $247.8 million and $278.1 million, respectively, in cash and money market funds consisting principally of U.S. Government-issued securities and high quality, short-term commercial paper which were classified as cash and cash equivalents.

 

Fair Value of Financial Instruments

 

Fair value is defined under ASC Topic 820, “Fair Value Measurements and Disclosures,” as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date.  Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs.  The standard describes a fair value hierarchy to measure fair value which is based on three levels of inputs, of which the first two are considered observable and the last unobservable, as follows:

 

·

Level 1 - Quoted prices in active markets for identical assets or liabilities.

 

·

Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

 

·

Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

 

As of September 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.  The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of September 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at September 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

240,643 

 

$

240,643 

 

$

 

$

 

 

As of June 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of June 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at June 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

269,304 

 

$

269,304 

 

$

 

$

 

 

The fair value of the Company’s cash equivalents is based primarily on quoted prices from active markets.

 

Unbilled Revenue

 

The majority of the Company’s unbilled revenue at September 30, 2015 and June 30, 2015 represents research funding earned prior to those dates based on actual resources utilized under the Company’s agreements with various collaborators.

 

Inventory

 

Inventory costs relate to clinical trial materials being manufactured for sale to the Company’s collaborators. Inventory is stated at the lower of cost or market as determined on a first-in, first-out (FIFO) basis.

 

Inventory at September 30, 2015 and June 30, 2015 is summarized below (in thousands):

 

 

 

September 30,
2015

 

June 30,
2015

 

 

 

 

 

 

 

Raw materials

 

$

76 

 

$

279 

 

Work in process

 

1,170 

 

2,656 

 

 

 

 

 

 

 

Total

 

$

1,246 

 

$

2,935 

 

 

Raw materials inventory consists entirely of DM1 and DM4, proprietary cell-killing agents the Company developed as part of its ADC technology. The Company considers more than a twelve month supply of raw materials that is not supported by firm, fixed orders and/or projections from its collaborators to be excess and establishes a reserve to reduce to zero the value of any such excess raw material inventory with a corresponding charge to research and development expense. In accordance with this policy, the Company recorded no expense related to excess inventory during the three-month period ended September 30, 2015 and $337,000 of expense during the three months ended September 30, 2014.

 

Work in process inventory consists of conjugate manufactured for sale to the Company’s collaborators to be used in preclinical and clinical studies.  All conjugate is made to order at the request of the collaborators and subject to the terms and conditions of respective supply agreements.  As such, no reserve for work in process inventory is required.

 

Computation of Net Loss per Common Share

 

Basic and diluted net loss per share is calculated based upon the weighted average number of common shares outstanding during the period. During periods of income, participating securities are allocated a proportional share of income determined by dividing total weighted average participating securities by the sum of the total weighted average common shares and participating securities (the “two-class method”). Shares of the Company’s restricted stock participate in any dividends declared by the Company and are therefore considered to be participating securities. Participating securities have the effect of diluting both basic and diluted earnings per share during periods of income. During periods of loss, no loss is allocated to participating securities since they have no contractual obligation to share in the losses of the Company. Diluted (loss) income per share is computed after giving consideration to the dilutive effect of stock options and restricted stock that are outstanding during the period, except where such non-participating securities would be anti-dilutive.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Options outstanding to purchase common stock and unvested restricted stock (in thousands)

 

11,494 

 

10,564 

 

 

 

 

 

 

 

Common stock equivalents under treasury stock method

 

1,296 

 

1,147 

 

 

The Company’s common stock equivalents have not been included in any net loss per share calculation because their effect is anti-dilutive due to the Company’s net loss position.

 

Stock-Based Compensation

 

As of September 30, 2015, the Company is authorized to grant future awards under one employee share-based compensation plan, which is the ImmunoGen, Inc. 2006 Employee, Director and Consultant Equity Incentive Plan, or the 2006 Plan. At the annual meeting of shareholders on November 11, 2014, an amendment to the 2006 Plan was approved and an additional 5,500,000 shares were authorized for issuance under this plan.  As amended, the 2006 Plan provides for the issuance of Stock Grants, the grant of Options and the grant of Stock-Based Awards for up to 17,500,000 shares of the Company’s common stock, as well as 1,676,599 shares of common stock which represent awards granted under the previous stock option plan, the ImmunoGen, Inc. Restated Stock Option Plan, or the Former Plan, that were forfeited, expired or were cancelled without delivery of shares of common stock or which resulted in the forfeiture of shares of common stock back to the Company between November 11, 2006 and June 30, 2014. Option awards are granted with an exercise price equal to the market price of the Company’s stock at the date of grant. Options vest at various periods of up to four years and may be exercised within ten years of the date of grant.

 

The stock-based awards are accounted for under ASC Topic 718, “Compensation—Stock Compensation.” Pursuant to Topic 718, the estimated grant date fair value of awards is charged to the statement of operations and comprehensive loss over the requisite service period, which is the vesting period. Such amounts have been reduced by an estimate of forfeitures of all unvested awards. The fair value of each stock option is estimated on the date of grant using the Black-Scholes option-pricing model with the assumptions noted in the following table. As the Company has not paid dividends since inception, nor does it expect to pay any dividends for the foreseeable future, the expected dividend yield assumption is zero. Expected volatility is based exclusively on historical volatility data of the Company’s stock. The expected term of stock options granted is based exclusively on historical data and represents the period of time that stock options granted are expected to be outstanding. The expected term is calculated for and applied to one group of stock options as the Company does not expect substantially different exercise or post-vesting termination behavior among its option recipients. The risk-free rate of the stock options is based on the U.S. Treasury rate in effect at the time of grant for the expected term of the stock options.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Dividend

 

None

 

None

 

Volatility

 

67.07 

%

60.44 

%

Risk-free interest rate

 

1.89 

%

1.88 

%

Expected life (years)

 

6.3 

 

6.3 

 

 

Using the Black-Scholes option-pricing model, the weighted average grant date fair values of options granted during the three months ended September 30, 2015 and 2014 were $10.31 and $6.27 per share, respectively.

 

Stock compensation expense related to stock options and restricted stock awards granted under the 2006 Plan was $5.7 million and $5.3 million during the three months ended September 30, 2015 and 2014, respectively. As of September 30, 2015, the estimated fair value of unvested employee awards was $35 million, net of estimated forfeitures. The weighted-average remaining vesting period for these awards is approximately two and a half years.

 

During the three months ended September 30, 2015, holders of options issued under the Company’s equity plans exercised their rights to acquire an aggregate of approximately 402,000 shares of common stock at prices ranging from $3.19 to $17.00 per share.  The total proceeds to the Company from these option exercises were approximately $4.5 million.

 

Segment Information

 

During the three months ended September 30, 2015, the Company continued to operate in one operating segment which is the business of discovery of monoclonal antibody-based anticancer therapeutics.

 

The percentages of revenues recognized from significant customers of the Company in the three months ended September 30, 2015 and 2014 are included in the following table:

 

 

 

Three Months Ended
September 30,

 

Collaborative Partner:

 

2015

 

2014

 

Biotest

 

16 

%

11 

%

Lilly

 

35 

%

%

Sanofi

 

 

45 

%

Roche

 

38 

%

32 

%

 

There were no other customers of the Company with significant revenues in the three months ended September 30, 2015 and 2014.

 

Recent Accounting Pronouncements

 

In May 2014, the FASB issued Accounting Standards Update 2014-9, Revenue from Contracts with Customers (Topic 606) (“ASU 2014-09”), to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required the Company to adopt beginning in its first quarter of fiscal 2018. In July 2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.  Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. The Company is currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on its consolidated financial statements and related disclosures.

 

In August 2014, the FASB issued Accounting Standards Update 2014-15, Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern. This new standard gives a company’s management the final responsibilities to decide whether there’s substantial doubt about the company’s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company’s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

In April 2015, the FASB issued Accounting Standards Update 2015-03, Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs. To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.  The recognition and measurement guidance for debt issuance costs are not affected by this update.  This guidance is effective for annual reporting beginning after December 15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2016. The Company’s consolidated balance sheet as of September 30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.

 

In July 2015, the FASB issued Accounting Standards Update 2015-11, Simplifying the Measurement of Inventory (Topic 330). To simplify the principles for subsequent measurement of inventory, this new standard requires inventory measured using any method other than LIFO or the retail method shall be measured at the lower of cost and net realizable value, rather than lower of cost or market. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, and calls for prospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

XML 18 R22.htm IDEA: XBRL DOCUMENT v3.3.0.814
Collaborative Agreements (Details 3)
$ in Thousands
1 Months Ended 3 Months Ended 147 Months Ended
Oct. 31, 2015
USD ($)
Dec. 31, 2013
USD ($)
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
Sep. 30, 2015
USD ($)
Dec. 31, 2006
USD ($)
Jul. 31, 2003
USD ($)
Collaborative Agreements disclosures              
License and milestone fees     $ 6,070 $ 6,234      
Sanofi | Development and Commercialization License              
Collaborative Agreements disclosures              
Number of undisclosed targets with exclusive licenses | item     1        
Potential milestone payments           $ 30,000 $ 21,500
Payments received under collaboration agreement         $ 20,500    
License exercise fee, per license           2,000  
Fee received per license   $ 2,000          
License and milestone fees       1,700      
Sanofi | Development and Commercialization License | Phase I clinical trial | Subsequent event              
Collaborative Agreements disclosures              
License and milestone fees $ 2,000            
Sanofi | Development and Commercialization License | Phase IIb clinical trial              
Collaborative Agreements disclosures              
Potential milestone payments     $ 4,000   $ 4,000    
Sanofi | Development and Commercialization License | Development milestones              
Collaborative Agreements disclosures              
Potential milestone payments           10,000 7,500
Sanofi | Development and Commercialization License | Regulatory milestones              
Collaborative Agreements disclosures              
Potential milestone payments           $ 20,000 $ 14,000
Sanofi | Development and Commercialization License | SAR650984 | Phase IIb clinical trial              
Collaborative Agreements disclosures              
Payments received under collaboration agreement       3,000      
Sanofi | Development and Commercialization License | SAR408701 | Phase I clinical trial              
Collaborative Agreements disclosures              
Payments received under collaboration agreement       $ 1,000      
XML 19 R24.htm IDEA: XBRL DOCUMENT v3.3.0.814
Capital Stock (Details) - USD ($)
3 Months Ended 12 Months Ended 135 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Jun. 30, 2015
Jun. 30, 2014
Sep. 30, 2015
Stock-Based Compensation          
Compensation expense (expense reduction) $ 5,783,000 $ 5,410,000      
Stock options granted to directors (in shares) 1,676,599        
2001 Director Plan | Stock options          
Stock-Based Compensation          
Compensation expense (expense reduction) $ (30,000) (8,000)      
Stock units issued (in shares)         0
Compensation Policy for Non-Employee Directors | Stock options          
Stock-Based Compensation          
Vesting period 1 year        
Stock options granted to directors (in shares)     80,000 80,000  
Compensation Policy for Non-Employee Directors | Deferred share units          
Stock-Based Compensation          
Stock compensation expense $ 82,000 $ 118,000      
Vesting period 1 year        
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Collaborative Agreements
3 Months Ended
Sep. 30, 2015
Collaborative Agreements  
Collaborative Agreements

B.Collaborative Agreements

 

Lilly

 

Eli Lilly and Company (Lilly) had the right to take three exclusive development and commercialization licenses under a right-to-test agreement established in December 2011, and took these licenses prior to the expiration of the agreement in December 2014. The Company received a $20 million upfront payment in connection with the execution of the right-to-test agreement in 2011.  Under the terms of this right-to-test agreement, the first license had no associated exercise fee, and the second and third licenses each had a $2 million exercise fee. The first development and commercialization license was taken in August 2013 and the agreement was amended in December 2013 to provide Lilly with an extension provision and retrospectively include a $2 million exercise fee for the first license in lieu of the fee due for either the second or third license. The second and third licenses were taken in December 2014, with one including the $2 million exercise fee and the other not. Under the two licenses with the $2 million exercise fee, the Company is entitled to receive up to a total of $199 million in milestone payments, plus royalties on the commercial sales of any resulting products.  Under the license taken in December 2014 without the exercise fee, the Company is entitled to receive up to a total of $200.5 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$29 million for the two development and commercialization licenses with the $2 million exercise fee, and $30.5 million for the one development and commercialization license with no exercise fee; regulatory milestones—$70 million in all cases; and sales milestones—$100 million in all cases.

 

In September 2015, Lilly initiated Phase I, first-in-human clinical testing of its ADC product candidate, LY3076226, triggering a $5 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September 30, 2015.  The next payment the Company could receive would be either a $9 million milestone for commencement of a Phase II clinical trial under this license or a $5 million development milestone payment with the commencement of a Phase I clinical trial under either of its other two licenses.  At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s expected involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive. The Company also is entitled to receive payments for delivery of cytotoxic agents to Lilly and research and development activities performed on behalf of Lilly. Lilly is responsible for the manufacturing, product development and marketing of any products resulting from this collaboration.

 

Amgen

 

Under a now-expired right-to-test agreement, in September 2009, November 2009 and December 2012, Amgen took three exclusive development and commercialization licenses, for which the Company received an exercise fee of $1 million for each license taken. In May 2013, Amgen took one non-exclusive development and commercialization license, for which the Company received an exercise fee of $500,000. In October 2013, the non-exclusive license was amended and converted to an exclusive license, for which Amgen paid an additional $500,000 fee to the Company. Amgen has sublicensed its rights under this license to Oxford BioTherapeutics Ltd. For each development and commercialization license taken, the Company is entitled to receive up to a total of $34 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones per license are categorized as follows: development milestones—$9 million; regulatory milestones—$20 million; and sales milestones—$5 million. Amgen (or its sublicensee(s)) is responsible for the manufacturing, product development and marketing of any products resulting from these development and commercialization licenses.

 

In September 2015, the IND application for its third ADC product candidate became effective, triggering a $1 million milestone payment to the Company which is included in license and milestone fee revenue for the three months ended September 30, 2015. In November 2011, the IND applications to the FDA for its product candidates AMG 595 and AMG 172 became effective, which triggered two $1 million milestone payments to the Company. The next potential milestone the Company will be entitled to receive under these three licenses will be a development milestone for the first dosing of a patient in a Phase II clinical trial, which will result in a $3 million payment being due. The next potential milestone the Company will be entitled to receive under the May 2013 license will be a $1 million development milestone for an IND becoming effective. At the time of execution of each of these development and commercialization licenses, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s past involvement in the research and manufacturing of these product candidates, these milestones were deemed substantive.

 

Sanofi

 

In July 2003, the Company entered into a broad collaboration agreement with Sanofi (formerly Aventis) to discover, develop and commercialize antibody-based products. The collaboration agreement provides Sanofi with worldwide development and commercialization rights to new antibody-based products directed to targets that are included in the collaboration, including the exclusive right to use the Company’s maytansinoid ADC technology in the creation of products developed to these targets. The product candidates (targets) as of September 30, 2015 in the collaboration include SAR650984 (CD38), SAR566658 (CA6), SAR408701 (CEACAM5) and one earlier-stage compound that has yet to be disclosed.

 

We are entitled to receive milestone payments potentially totaling $21.5 million, per target, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$7.5 million; and regulatory milestones—$14 million. Through September 30, 2015, the Company has received and recognized an aggregate of $20.5 million in milestone payments for compounds covered under this agreement now or in the past, including a $3 million development milestone related to initiation of a Phase IIb clinical trial (as defined in the agreement) for SAR650984 and a $1 million development milestone related to initiation of a Phase I clinical trial for SAR408701 which are included in license and milestone fee revenue for the three months ended September 30, 2014.

 

In December 2006, we entered into a right-to-test agreement with Sanofi. The agreement provides Sanofi with the right to (a) test the Company’s maytansinoid ADC technology with Sanofi’s antibodies to targets under a right-to-test, or research, license, (b) take exclusive options, with certain restrictions, to specified targets for specified option periods and (c) upon exercise of those options, take exclusive licenses to use the Company’s maytansinoid ADC technology to develop and commercialize products directed to the specified targets on terms agreed upon at the inception of the right-to-test agreement. Sanofi no longer has the right to take additional options under the agreement, although multiple outstanding options remain in effect for the remainder of their respective option periods. For each development and commercialization license taken, the Company is entitled to receive an exercise fee of $2 million and up to a total of $30 million in milestone payments, plus royalties on the commercial sales of any resulting products. The total milestones are categorized as follows: development milestones—$10 million; and regulatory milestones—$20 million.

 

In December 2013, Sanofi took its first exclusive development and commercialization license under the right-to-test agreement, for which the Company received an exercise fee of $2 million and was recognizing this amount as revenue ratably over the Company’s estimated period of its substantial involvement. The Company had previously estimated this development period would conclude at the end of non-pivotal Phase II testing.  During the first quarter of fiscal 2015, the Company determined it will not be substantially involved in the development and commercialization of the product based on Sanofi’s current plans to develop and manufacture the product without the Company’s assistance. As a result of this determination, we recognized the balance of the upfront exercise fee during the prior period.  This change in estimate resulted in an increase to license and milestone fees of $1.7 million for the three months ended September 30, 2014 compared to amounts that would have been recognized pursuant to the Company’s previous estimate.

 

Pursuant to the license agreement noted above, in October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The next milestone payment the Company could receive would be a $4 million development milestone for commencement of a Phase IIb clinical trial (as defined in the agreement) under this license. At the time of execution of this agreement, there was significant uncertainty as to whether these milestones would be achieved. In consideration of this, as well as the Company’s past involvement in the research and manufacturing of Sanofi’s product candidates, these milestones were deemed substantive.

 

For additional information related to these agreements, as well as the Company’s other significant collaborative agreements, please read Note C, Agreements to our consolidated financial statements included within the Company’s 2015 Form 10-K.

 

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CONSOLIDATED BALANCE SHEETS (Parenthetical) - $ / shares
shares in Thousands
Sep. 30, 2015
Jun. 30, 2015
CONSOLIDATED BALANCE SHEETS    
Preferred stock, par value (in dollars per share) $ 0.01 $ 0.01
Preferred stock, authorized shares 5,000 5,000
Preferred stock, shares issued 0 0
Preferred stock, shares outstanding 0 0
Common stock, par value (in dollars per share) $ 0.01 $ 0.01
Common stock, authorized shares 150,000 150,000
Common stock, issued shares 86,981 86,579
Common stock, outstanding shares 86,981 86,579
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Summary of Significant Accounting Policies (Details 3) - USD ($)
shares in Thousands
3 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Jun. 30, 2015
Inventory      
Raw materials $ 76,000   $ 279,000
Work in process 1,170,000   2,656,000
Total $ 1,246,000   $ 2,935,000
Minimum supply period of raw materials that is not supported by firm, fixed orders and/or projections from collaborators considered to expense inventory 12 months    
Charges to research and development expense related to raw material inventory identified as excess $ 0 $ 337,000  
Reserve for work in process $ 0    
Computation of Net Income (Loss) per Common Share      
Options outstanding to purchase common stock and unvested restricted stock (in shares) 11,494 10,564  
Common stock equivalents under treasury stock method (in shares) 1,296 1,147  

XML 25 R1.htm IDEA: XBRL DOCUMENT v3.3.0.814
Document and Entity Information - shares
3 Months Ended
Sep. 30, 2015
Oct. 27, 2015
Document and Entity Information    
Entity Registrant Name IMMUNOGEN INC  
Entity Central Index Key 0000855654  
Document Type 10-Q  
Document Period End Date Sep. 30, 2015  
Amendment Flag false  
Current Fiscal Year End Date --06-30  
Entity Current Reporting Status Yes  
Entity Filer Category Large Accelerated Filer  
Entity Common Stock, Shares Outstanding   86,984,630
Document Fiscal Year Focus 2016  
Document Fiscal Period Focus Q1  
XML 26 R18.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Details 4)
$ / shares in Units, $ in Thousands
3 Months Ended
Nov. 11, 2014
shares
Sep. 30, 2015
USD ($)
item
$ / shares
shares
Sep. 30, 2014
USD ($)
$ / shares
Additional disclosure for options      
Cash received for exercise of stock options | $   $ 4,462 $ 144
Number of Stock Options      
Granted (in shares)   1,676,599  
2006 Plan      
Stock-Based Compensation      
Number of employee share-based compensation plans | item   1  
Additional number of shares authorized for issuance 5,500,000    
Common stock authorized for issuance (in shares) 17,500,000    
Additional disclosure for options      
Stock compensation expense | $   $ 5,700 $ 5,300
Estimated fair value of unvested employee awards, net of estimated forfeitures | $   $ 35,000  
Weighted average vesting period of unvested employee awards   2 years 6 months  
2006 Plan | Stock options      
Weighted-average assumptions used to estimate the fair value of each stock option      
Number of group of awards for which expected term is calculated for and applied | item   1  
Dividend (as a percent)   0.00% 0.00%
Volatility (as a percent)   67.07% 60.44%
Risk-free interest rate (as a percent)   1.89% 1.88%
Expected life   6 years 3 months 18 days 6 years 3 months 18 days
Weighted-average grant date fair values of options granted (in dollars per share) | $ / shares   $ 10.31 $ 6.27
Additional disclosure for options      
Stock options exercised (in shares)   402,000  
Cash received for exercise of stock options | $   $ 4,500  
2006 Plan | Stock options | Maximum      
Stock-Based Compensation      
Vesting period   4 years  
Exercise period   10 years  
Additional disclosure for options      
Exercised (in dollars per share) | $ / shares   $ 17.00  
2006 Plan | Stock options | Minimum      
Additional disclosure for options      
Exercised (in dollars per share) | $ / shares   $ 3.19  
XML 27 R4.htm IDEA: XBRL DOCUMENT v3.3.0.814
CONSOLIDATED STATEMENTS OF OPERATIONS AND COMPREHENSIVE LOSS - USD ($)
shares in Thousands, $ in Thousands
3 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Revenues:    
License and milestone fees $ 6,070 $ 6,234
Royalty revenue   4,166
Non-cash royalty revenue related to the sale of future royalties 5,684  
Research and development support 772 776
Clinical materials revenue 2,325 2,027
Total revenues 14,851 13,203
Operating Expenses:    
Research and development 35,132 28,018
General and administrative 8,329 7,095
Total operating expenses 43,461 35,113
Loss from operations (28,610) (21,910)
Investment income, net 51 8
Non-cash interest expense on liability related to the sale of future royalties (5,143)  
Other expense, net (38) (380)
Net loss $ (33,740) $ (22,282)
Basic and diluted net loss per common share (in dollars per share) $ (0.39) $ (0.26)
Basic and diluted weighted average common shares outstanding (in shares) 86,838 85,872
Total comprehensive loss $ (33,740) $ (22,282)
XML 28 R12.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Tables)
3 Months Ended
Sep. 30, 2015
Summary of Significant Accounting Policies  
Schedule of assets that are required to be measured at fair value on a recurring basis

 

As of September 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.  The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of September 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at September 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

240,643 

 

$

240,643 

 

$

 

$

 

 

As of June 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of June 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at June 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

269,304 

 

$

269,304 

 

$

 

$

 

 

Schedule of inventory

 

Inventory at September 30, 2015 and June 30, 2015 is summarized below (in thousands):

 

 

 

September 30,
2015

 

June 30,
2015

 

 

 

 

 

 

 

Raw materials

 

$

76 

 

$

279 

 

Work in process

 

1,170 

 

2,656 

 

 

 

 

 

 

 

Total

 

$

1,246 

 

$

2,935 

 

 

 

 

Schedule of common stock equivalents, as calculated in accordance with the treasury-stock method

 

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Options outstanding to purchase common stock and unvested restricted stock (in thousands)

 

11,494 

 

10,564 

 

 

 

 

 

 

 

Common stock equivalents under treasury stock method

 

1,296 

 

1,147 

 

 

Schedule of weighted-average assumptions used to estimate the fair value of each stock option

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Dividend

 

None

 

None

 

Volatility

 

67.07 

%

60.44 

%

Risk-free interest rate

 

1.89 

%

1.88 

%

Expected life (years)

 

6.3 

 

6.3 

 

 

Schedule of percentage of total revenues recognized from each significant customer

 

 

 

Three Months Ended
September 30,

 

Collaborative Partner:

 

2015

 

2014

 

Biotest

 

16 

%

11 

%

Lilly

 

35 

%

%

Sanofi

 

 

45 

%

Roche

 

38 

%

32 

%

 

 

XML 29 R11.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Policies)
3 Months Ended
Sep. 30, 2015
Summary of Significant Accounting Policies  
Basis of Presentation

Basis of Presentation

 

The accompanying unaudited consolidated financial statements at September 30, 2015 and June 30, 2015 and for the three months ended September 30, 2015 and 2014 include the accounts of ImmunoGen, Inc., or the Company, and its wholly owned subsidiaries, ImmunoGen Securities Corp., ImmunoGen Europe Limited and Hurricane, LLC. The consolidated financial statements include all of the adjustments, consisting only of normal recurring adjustments, which management considers necessary for a fair presentation of the Company’s financial position in accordance with accounting principles generally accepted in the U.S. for interim financial information. The June 30, 2015 condensed consolidated balance sheet data presented for comparative purposes was derived from our audited financial statements but certain information and footnote disclosures normally included in the Company’s annual financial statements have been condensed or omitted. The preparation of interim financial statements requires the use of management’s estimates and assumptions that affect the reported amounts of assets and liabilities and disclosure of contingent assets and liabilities at the date of the interim financial statements and the reported amounts of revenues and expenditures during the reported periods. The results of the interim periods are not necessarily indicative of the results for the entire year. Accordingly, the interim financial statements should be read in conjunction with the audited financial statements and notes thereto included in the Company’s Annual Report on Form 10-K for the year ended June 30, 2015.

 

 

Subsequent Events

Subsequent Events

 

The Company has evaluated all events or transactions that occurred after September 30, 2015 up through the date the Company issued these financial statements. In October 2015, Sanofi initiated Phase I, first-in-human clinical testing of its ADC product candidate, SAR428926, triggering a $2 million development milestone payment to the Company. The Company did not have any other material recognizable or unrecognizable subsequent events during this period.

 

Revenue Recognition

Revenue Recognition

 

The Company enters into licensing and development agreements with collaborative partners for the development of monoclonal antibody-based anticancer therapeutics. The terms of these agreements contain multiple deliverables which may include (i) licenses, or options to obtain licenses, to the Company’s antibody-drug conjugate, or ADC, technology, (ii) rights to future technological improvements, (iii) research activities to be performed on behalf of the collaborative partner, (iv) delivery of cytotoxic agents and (v) the manufacture of preclinical or clinical materials for the collaborative partner. Payments to the Company under these agreements may include upfront fees, option fees, exercise fees, payments for research activities, payments for the manufacture of preclinical or clinical materials, payments based upon the achievement of certain milestones and royalties on product sales. The Company follows the provisions of the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) Topic 605-25, “Revenue Recognition—Multiple-Element Arrangements,” and ASC Topic 605-28, “Revenue Recognition-Milestone Method,” in accounting for these agreements. In order to account for these agreements, the Company must identify the deliverables included within the agreement and evaluate which deliverables represent separate units of accounting based on if certain criteria are met, including whether the delivered element has stand-alone value to the collaborator. The consideration received is allocated among the separate units of accounting, and the applicable revenue recognition criteria are applied to each of the separate units.

 

At September 30, 2015, the Company had the following two types of agreements with the parties identified below:

 

·

Development and commercialization licenses, which provide the party with the right to use the Company’s ADC technology and/or certain other intellectual property to develop compounds to a specified antigen target:

 

Amgen (four exclusive single-target licenses(1))

 

Bayer HealthCare (one exclusive single-target license)

 

Biotest (one exclusive single-target license)

 

Lilly (three exclusive single-target licenses)

 

 

(1)

Amgen has sublicensed one of its exclusive single-target licenses to Oxford BioTherapeutics Ltd.

 

 

 

Novartis (five exclusive single-target licenses and one license to two related targets: one target on an exclusive basis and the second target on a non-exclusive basis)

 

Roche, through its Genentech unit (five exclusive single-target licenses)

 

Sanofi (one exclusive single-target license and one exclusive license to multiple individual targets)

 

·

Research license/option agreement for a defined period of time to secure development and commercialization licenses to use the Company’s ADC technology to develop anticancer compounds to specified targets on established terms (referred to herein as right-to-test agreements):

 

Sanofi

 

CytomX

 

Takeda, through its wholly owned subsidiary, Millennium Pharmaceuticals, Inc.

 

There are no performance, cancellation, termination or refund provisions in any of the arrangements that contain material financial consequences to the Company.

 

Development and Commercialization Licenses

 

The deliverables under a development and commercialization license agreement generally include the license to the Company’s ADC technology with respect to a specified antigen target, and may also include deliverables related to rights to future technological improvements, research activities to be performed on behalf of the collaborative partner and the manufacture of preclinical or clinical materials for the collaborative partner.

 

Generally, development and commercialization licenses contain non-refundable terms for payments and, depending on the terms of the agreement, provide that the Company will (i) at the collaborator’s request, provide research services at negotiated prices which are generally consistent with what other third parties would charge, (ii) at the collaborator’s request, manufacture and provide to it preclinical and clinical materials or deliver cytotoxic agents at negotiated prices which are generally consistent with what other third parties would charge, (iii) earn payments upon the achievement of certain milestones and (iv) earn royalty payments, generally until the later of the last applicable patent expiration or 10 to 12 years after product launch. In the case of Kadcyla, however, the minimum royalty term is 10 years and the maximum royalty term is 12 years on a country by country basis, regardless of patent protection.  Royalty rates may vary over the royalty term depending on the Company’s intellectual property rights and/or the presence of comparable competing products. The Company may provide technical assistance and share any technology improvements with its collaborators during the term of the collaboration agreements. The Company does not directly control when or whether any collaborator will request research or manufacturing services, achieve milestones or become liable for royalty payments. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

In determining the units of accounting, management evaluates whether the license has stand-alone value from the undelivered elements to the collaborative partner based on the consideration of the relevant facts and circumstances for each arrangement. Factors considered in this determination include the research capabilities of the partner and the availability of ADC technology research expertise in the general marketplace. If the Company concludes that the license has stand-alone value and therefore will be accounted for as a separate unit of accounting, the Company then determines the estimated selling prices of the license and all other units of accounting based on market conditions, similar arrangements entered into by third parties, and entity-specific factors such as the terms of the Company’s previous collaborative agreements, recent preclinical and clinical testing results of therapeutic products that use the Company’s ADC technology, the Company’s pricing practices and pricing objectives, the likelihood that technological improvements will be made, and, if made, will be used by the Company’s collaborators and the nature of the research services to be performed on behalf of its collaborators and market rates for similar services.

 

Upfront payments on development and commercialization licenses are deferred if facts and circumstances dictate that the license does not have stand-alone value. Prior to the adoption of Accounting Standards Update (ASU) No. 2009-13, “Revenue Arrangements with Multiple Deliverables” on July 1, 2010, the Company determined that its licenses lacked stand-alone value and were combined with other elements of the arrangement and any amounts associated with the license were deferred and amortized over a certain period, which the Company refers to as the Company’s period of substantial involvement. The determination of the length of the period over which to defer revenue is subject to judgment and estimation and can have an impact on the amount of revenue recognized in a given period. Historically the Company’s involvement with the development of a collaborator’s product candidate has been significant at the early stages of development, and lessens as it progresses into clinical trials. Also, as a drug candidate gets closer to commencing pivotal testing the Company’s collaborators have sought an alternative site to manufacture their products, as the Company’s facility does not produce pivotal or commercial drug product. Accordingly, the Company generally estimates this period of substantial involvement to begin at the inception of the collaboration agreement and conclude at the end of non-pivotal Phase II testing. The Company believes this period of substantial involvement is, depending on the nature of the license, on average six and one-half years. Quarterly, the Company reassesses its periods of substantial involvement over which the Company amortizes its upfront license fees and makes adjustments as appropriate. In the event a collaborator elects to discontinue development of a specific product candidate under a development and commercialization license, but retains its right to use the Company’s technology to develop an alternative product candidate to the same target or a target substitute, the Company would cease amortization of any remaining portion of the upfront fee until there is substantial preclinical activity on another product candidate and its remaining period of substantial involvement can be estimated. In the event that a development and commercialization license were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination.

 

Subsequent to the adoption of ASU No. 2009-13, the Company determined that its research licenses lack stand-alone value and are considered for aggregation with the other elements of the arrangement and accounted for as one unit of accounting.

 

Upfront payments on development and commercialization licenses may be recognized upon delivery of the license if facts and circumstances dictate that the license has stand-alone value from the undelivered elements, which generally include rights to future technological improvements, research services, delivery of cytotoxic agents and the manufacture of preclinical and clinical materials.

 

The Company recognizes revenue related to research services that represent separate units of accounting as they are performed, as long as there is persuasive evidence of an arrangement, the fee is fixed or determinable, and collection of the related receivable is probable. The Company recognizes revenue related to the rights to future technological improvements over the estimated term of the applicable license.

 

The Company may also provide cytotoxic agents to its collaborators or produce preclinical and clinical materials at negotiated prices which are generally consistent with what other third parties would charge. The Company recognizes revenue on cytotoxic agents and on preclinical and clinical materials when the materials have passed all quality testing required for collaborator acceptance and title and risk of loss have transferred to the collaborator. Arrangement consideration allocated to the manufacture of preclinical and clinical materials in a multiple-deliverable arrangement is below the Company’s full cost, and the Company’s full cost is not expected to ever be below its contract selling prices for its existing collaborations. During the three months ended September 30, 2015 and 2014, the difference between the Company’s full cost to manufacture preclinical and clinical materials on behalf of its collaborators as compared to total amounts received from collaborators for the manufacture of preclinical and clinical materials was $7.0 million and $3.1 million, respectively. The majority of the Company’s costs to produce these preclinical and clinical materials are fixed and then allocated to each batch based on the number of batches produced during the period. Therefore, the Company’s costs to produce these materials are significantly impacted by the number of batches produced during the period. The volume of preclinical and clinical materials the Company produces is directly related to the number of clinical trials the Company and its collaborators are preparing for or currently have underway, the speed of enrollment in those trials, the dosage schedule of each clinical trial and the time period such trials last. Accordingly, the volume of preclinical and clinical materials produced, and therefore the Company’s per-batch costs to manufacture these preclinical and clinical materials, may vary significantly from period to period.

 

The Company may also produce research material for potential collaborators under material transfer agreements. Additionally, the Company performs research activities, including developing antibody specific conjugation processes, on behalf of its collaborators and potential collaborators during the early evaluation and preclinical testing stages of drug development. The Company records amounts received for research materials produced or services performed as a component of research and development support revenue. The Company also develops conjugation processes for materials for later-stage testing and commercialization for certain collaborators. The Company is compensated at negotiated rates and may receive milestone payments for developing these processes which are recorded as a component of research and development support revenue.

 

The Company’s development and commercialization license agreements have milestone payments which for reporting purposes are aggregated into three categories: (i) development milestones, (ii) regulatory milestones, and (iii) sales milestones. Development milestones are typically payable when a product candidate initiates or advances into different clinical trial phases. Regulatory milestones are typically payable upon submission for marketing approval with the U.S. Food and Drug Administration, or FDA, or other countries’ regulatory authorities or on receipt of actual marketing approvals for the compound or for additional indications. Sales milestones are typically payable when annual sales reach certain levels.

 

At the inception of each agreement that includes milestone payments, the Company evaluates whether each milestone is substantive and at risk to both parties on the basis of the contingent nature of the milestone. This evaluation includes an assessment of whether (a) the consideration is commensurate with either (1) the entity’s performance to achieve the milestone, or (2) the enhancement of the value of the delivered item(s) as a result of a specific outcome resulting from the entity’s performance to achieve the milestone, (b) the consideration relates solely to past performance and (c) the consideration is reasonable relative to all of the deliverables and payment terms within the arrangement. The Company evaluates factors such as the scientific, regulatory, commercial and other risks that must be overcome to achieve the respective milestone, the level of effort and investment required to achieve the respective milestone and whether the milestone consideration is reasonable relative to all deliverables and payment terms in the arrangement in making this assessment.

 

Non-refundable development and regulatory milestones that are expected to be achieved as a result of the Company’s efforts during the period of substantial involvement are considered substantive and are recognized as revenue upon the achievement of the milestone, assuming all other revenue recognition criteria are met. Milestones that are not considered substantive because the Company does not contribute effort to the achievement of such milestones are generally achieved after the period of substantial involvement and are recognized as revenue upon achievement of the milestone, as there are no undelivered elements remaining and no continuing performance obligations, assuming all other revenue recognition criteria are met.

 

Under the Company’s development and commercialization license agreements, the Company receives royalty payments based upon its licensees’ net sales of covered products. Generally, under these agreements the Company is to receive royalty reports and payments from its licensees approximately one quarter in arrears, that is, generally in the third month of the quarter after the licensee has sold the royalty-bearing product or products. The Company recognizes royalty revenues when it can reliably estimate such amounts and collectability is reasonably assured. As such, the Company generally recognizes royalty revenues in the quarter reported to the Company by its licensees, or one quarter following the quarter in which sales by the Company’s licensees occurred.

 

Right-to-Test Agreements

 

The Company’s right-to-test agreements provide collaborators the right to (a) test the Company’s ADC technology for a defined period of time through a research, or right-to-test, license, (b) take options, for a defined period of time, to specified targets and (c) upon exercise of those options, secure or “take” licenses to develop and commercialize products for the specified targets on established terms. Under these agreements, fees may be due to the Company (i) at the inception of the arrangement (referred to as “upfront” fees or payments), (ii) upon taking an option with respect to a specific target (referred to as option fees or payments earned, if any, when the option is “taken”), (iii) upon the exercise of a previously taken option to acquire a development and commercialization license(s) (referred to as exercise fees or payments earned, if any, when the development and commercialization license is “taken”), or (iv) some combination of all of these fees.

 

The accounting for right-to-test agreements is dependent on the nature of the options granted to the collaborative partner. Options are considered substantive if, at the inception of a right-to-test agreement, the Company is at risk as to whether the collaborative partner will choose to exercise the options to secure development and commercialization licenses. Factors that are considered in evaluating whether options are substantive include the overall objective of the arrangement, the benefit the collaborator might obtain from the agreement without exercising the options, the cost to exercise the options relative to the total upfront consideration, and the additional financial commitments or economic penalties imposed on the collaborator as a result of exercising the options.

 

For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are considered substantive, the Company does not consider the development and commercialization licenses to be a deliverable at the inception of the agreement. For those right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 where the options to secure development and commercialization licenses are considered substantive, the Company has deferred the upfront payments received and recognizes this revenue over the period during which the collaborator could elect to take options for development and commercialization licenses. These periods are specific to each collaboration agreement. If a collaborator takes an option to acquire a development and commercialization license under these agreements, any substantive option fee is deferred and recognized over the life of the option, generally 12 to 18 months. If a collaborator exercises an option and takes a development and commercialization license to a specific target, the Company attributes the exercise fee to the development and commercialization license. Upon exercise of an option to acquire a development and commercialization license, the Company would also attribute any remaining deferred option fee to the development and commercialization license and apply the multiple-element revenue recognition criteria to the development and commercialization license and any other deliverables to determine the appropriate revenue recognition, which will be consistent with the Company’s accounting policy for upfront payments on single-target licenses. In the event a right-to-test agreement were to be terminated, the Company would recognize as revenue any portion of the upfront fee that had not previously been recorded as revenue, but was classified as deferred revenue, at the date of such termination. None of the Company’s right-to-test agreements entered into subsequent to the adoption of ASU No. 2009-13 has been determined to contain substantive options.

 

For right-to-test agreements where the options to secure development and commercialization licenses to the Company’s ADC technology are not considered substantive, the Company considers the development and commercialization licenses to be a deliverable at the inception of the agreement and applies the multiple-element revenue recognition criteria to determine the appropriate revenue recognition. None of the Company’s right-to-test agreements entered into prior to the adoption of ASU No. 2009-13 has been determined to contain non-substantive options.

 

The Company does not directly control when or if any collaborator will exercise its options for development and commercialization licenses. As a result, the Company cannot predict when or if it will recognize revenues in connection with any of the foregoing.

 

 

Financial Instruments and Concentration of Credit Risk

Financial Instruments and Concentration of Credit Risk

 

Cash and cash equivalents are primarily maintained with three financial institutions in the U.S. Deposits with banks may exceed the amount of insurance provided on such deposits. Generally, these deposits may be redeemed upon demand and, therefore, bear minimal risk. The Company’s cash equivalents consist of money market funds with underlying investments primarily being U.S. Government issued securities and high quality, short term commercial paper. Financial instruments that potentially subject the Company to concentrations of credit risk consist principally of cash, cash equivalents and marketable securities. The Company held no marketable securities as of September 30, 2015 and June 30, 2015. The Company’s investment policy, approved by the Board of Directors, limits the amount it may invest in any one type of investment, thereby reducing credit risk concentrations.

 

Cash and Cash Equivalents

Cash and Cash Equivalents

 

All highly liquid financial instruments with maturities of three months or less when purchased are considered cash equivalents. As of September 30, 2015 and June 30, 2015, the Company held $247.8 million and $278.1 million, respectively, in cash and money market funds consisting principally of U.S. Government-issued securities and high quality, short-term commercial paper which were classified as cash and cash equivalents.

 

Fair Value of Financial Instruments

Fair Value of Financial Instruments

 

Fair value is defined under ASC Topic 820, “Fair Value Measurements and Disclosures,” as the exchange price that would be received for an asset or paid to transfer a liability (an exit price) in the principal or most advantageous market for the asset or liability in an orderly transaction between market participants on the measurement date.  Valuation techniques used to measure fair value must maximize the use of observable inputs and minimize the use of unobservable inputs.  The standard describes a fair value hierarchy to measure fair value which is based on three levels of inputs, of which the first two are considered observable and the last unobservable, as follows:

 

·

Level 1 - Quoted prices in active markets for identical assets or liabilities.

 

·

Level 2 - Inputs other than Level 1 that are observable, either directly or indirectly, such as quoted prices for similar assets or liabilities; quoted prices in markets that are not active; or other inputs that are observable or can be corroborated by observable market data for substantially the full term of the assets or liabilities.

 

·

Level 3 - Unobservable inputs that are supported by little or no market activity and that are significant to the fair value of the assets or liabilities.

 

As of September 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis.  The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of September 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at September 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

240,643 

 

$

240,643 

 

$

 

$

 

 

As of June 30, 2015, the Company held certain assets that are required to be measured at fair value on a recurring basis. The following table represents the fair value hierarchy for the Company’s financial assets measured at fair value on a recurring basis as of June 30, 2015 (in thousands):

 

 

 

Fair Value Measurements at June 30, 2015 Using

 

 

 

 

 

Quoted Prices in
Active Markets for
Identical Assets

 

Significant Other
Observable Inputs

 

Significant
Unobservable
Inputs

 

 

 

Total

 

(Level 1)

 

(Level 2)

 

(Level 3)

 

Cash equivalents

 

$

269,304 

 

$

269,304 

 

$

 

$

 

 

The fair value of the Company’s cash equivalents is based primarily on quoted prices from active markets.

 

Unbilled Revenue

Unbilled Revenue

 

The majority of the Company’s unbilled revenue at September 30, 2015 and June 30, 2015 represents research funding earned prior to those dates based on actual resources utilized under the Company’s agreements with various collaborators.

 

 

Inventory

Inventory

 

Inventory costs relate to clinical trial materials being manufactured for sale to the Company’s collaborators. Inventory is stated at the lower of cost or market as determined on a first-in, first-out (FIFO) basis.

 

Inventory at September 30, 2015 and June 30, 2015 is summarized below (in thousands):

 

 

 

September 30,
2015

 

June 30,
2015

 

 

 

 

 

 

 

Raw materials

 

$

76 

 

$

279 

 

Work in process

 

1,170 

 

2,656 

 

 

 

 

 

 

 

Total

 

$

1,246 

 

$

2,935 

 

 

Raw materials inventory consists entirely of DM1 and DM4, proprietary cell-killing agents the Company developed as part of its ADC technology. The Company considers more than a twelve month supply of raw materials that is not supported by firm, fixed orders and/or projections from its collaborators to be excess and establishes a reserve to reduce to zero the value of any such excess raw material inventory with a corresponding charge to research and development expense. In accordance with this policy, the Company recorded no expense related to excess inventory during the three-month period ended September 30, 2015 and $337,000 of expense during the three months ended September 30, 2014.

 

Work in process inventory consists of conjugate manufactured for sale to the Company’s collaborators to be used in preclinical and clinical studies.  All conjugate is made to order at the request of the collaborators and subject to the terms and conditions of respective supply agreements.  As such, no reserve for work in process inventory is required.

 

Computation of Net Loss per Common Share

Computation of Net Loss per Common Share

 

Basic and diluted net loss per share is calculated based upon the weighted average number of common shares outstanding during the period. During periods of income, participating securities are allocated a proportional share of income determined by dividing total weighted average participating securities by the sum of the total weighted average common shares and participating securities (the “two-class method”). Shares of the Company’s restricted stock participate in any dividends declared by the Company and are therefore considered to be participating securities. Participating securities have the effect of diluting both basic and diluted earnings per share during periods of income. During periods of loss, no loss is allocated to participating securities since they have no contractual obligation to share in the losses of the Company. Diluted (loss) income per share is computed after giving consideration to the dilutive effect of stock options and restricted stock that are outstanding during the period, except where such non-participating securities would be anti-dilutive.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Options outstanding to purchase common stock and unvested restricted stock (in thousands)

 

11,494 

 

10,564 

 

 

 

 

 

 

 

Common stock equivalents under treasury stock method

 

1,296 

 

1,147 

 

 

The Company’s common stock equivalents have not been included in any net loss per share calculation because their effect is anti-dilutive due to the Company’s net loss position.

 

 

Stock-based Compensation

Stock-Based Compensation

 

As of September 30, 2015, the Company is authorized to grant future awards under one employee share-based compensation plan, which is the ImmunoGen, Inc. 2006 Employee, Director and Consultant Equity Incentive Plan, or the 2006 Plan. At the annual meeting of shareholders on November 11, 2014, an amendment to the 2006 Plan was approved and an additional 5,500,000 shares were authorized for issuance under this plan.  As amended, the 2006 Plan provides for the issuance of Stock Grants, the grant of Options and the grant of Stock-Based Awards for up to 17,500,000 shares of the Company’s common stock, as well as 1,676,599 shares of common stock which represent awards granted under the previous stock option plan, the ImmunoGen, Inc. Restated Stock Option Plan, or the Former Plan, that were forfeited, expired or were cancelled without delivery of shares of common stock or which resulted in the forfeiture of shares of common stock back to the Company between November 11, 2006 and June 30, 2014. Option awards are granted with an exercise price equal to the market price of the Company’s stock at the date of grant. Options vest at various periods of up to four years and may be exercised within ten years of the date of grant.

 

The stock-based awards are accounted for under ASC Topic 718, “Compensation—Stock Compensation.” Pursuant to Topic 718, the estimated grant date fair value of awards is charged to the statement of operations and comprehensive loss over the requisite service period, which is the vesting period. Such amounts have been reduced by an estimate of forfeitures of all unvested awards. The fair value of each stock option is estimated on the date of grant using the Black-Scholes option-pricing model with the assumptions noted in the following table. As the Company has not paid dividends since inception, nor does it expect to pay any dividends for the foreseeable future, the expected dividend yield assumption is zero. Expected volatility is based exclusively on historical volatility data of the Company’s stock. The expected term of stock options granted is based exclusively on historical data and represents the period of time that stock options granted are expected to be outstanding. The expected term is calculated for and applied to one group of stock options as the Company does not expect substantially different exercise or post-vesting termination behavior among its option recipients. The risk-free rate of the stock options is based on the U.S. Treasury rate in effect at the time of grant for the expected term of the stock options.

 

 

 

Three Months Ended
September 30,

 

 

 

2015

 

2014

 

Dividend

 

None

 

None

 

Volatility

 

67.07 

%

60.44 

%

Risk-free interest rate

 

1.89 

%

1.88 

%

Expected life (years)

 

6.3 

 

6.3 

 

 

Using the Black-Scholes option-pricing model, the weighted average grant date fair values of options granted during the three months ended September 30, 2015 and 2014 were $10.31 and $6.27 per share, respectively.

 

Stock compensation expense related to stock options and restricted stock awards granted under the 2006 Plan was $5.7 million and $5.3 million during the three months ended September 30, 2015 and 2014, respectively. As of September 30, 2015, the estimated fair value of unvested employee awards was $35 million, net of estimated forfeitures. The weighted-average remaining vesting period for these awards is approximately two and a half years.

 

During the three months ended September 30, 2015, holders of options issued under the Company’s equity plans exercised their rights to acquire an aggregate of approximately 402,000 shares of common stock at prices ranging from $3.19 to $17.00 per share.  The total proceeds to the Company from these option exercises were approximately $4.5 million.

 

Segment Information

Segment Information

 

During the three months ended September 30, 2015, the Company continued to operate in one operating segment which is the business of discovery of monoclonal antibody-based anticancer therapeutics.

 

The percentages of revenues recognized from significant customers of the Company in the three months ended September 30, 2015 and 2014 are included in the following table:

 

 

 

Three Months Ended
September 30,

 

Collaborative Partner:

 

2015

 

2014

 

Biotest

 

16 

%

11 

%

Lilly

 

35 

%

%

Sanofi

 

 

45 

%

Roche

 

38 

%

32 

%

 

There were no other customers of the Company with significant revenues in the three months ended September 30, 2015 and 2014.

 

Recent Accounting Pronouncements

Recent Accounting Pronouncements

 

In May 2014, the FASB issued Accounting Standards Update 2014-9, Revenue from Contracts with Customers (Topic 606) (“ASU 2014-09”), to clarify the principles for recognizing revenue. This update provides a comprehensive new revenue recognition model that requires revenue to be recognized in a manner to depict the transfer of goods or services to a customer at an amount that reflects the consideration expected to be received in exchange for those goods or services. The original effective date would have required the Company to adopt beginning in its first quarter of fiscal 2018. In July 2015, the FASB voted to amend ASU 2014-09 by approving a one-year deferral of the effective date as well as providing the option to early adopt the standard on the original effective date.  Accordingly, the Company may adopt the standard in either its first quarter of fiscal 2018 or 2019. The new revenue standard allows for either full retrospective or modified retrospective application. The Company is currently evaluating the timing of its adoption, the transition method to apply and the impact that this guidance will have on its consolidated financial statements and related disclosures.

 

In August 2014, the FASB issued Accounting Standards Update 2014-15, Presentation of Financial Statements-Going Concern (Subtopic 205-40): Disclosure of Uncertainties about an Entity’s Ability to Continue as a Going Concern. This new standard gives a company’s management the final responsibilities to decide whether there’s substantial doubt about the company’s ability to continue as a going concern and to provide related footnote disclosures. The standard provides guidance to management, with principles and definitions that are intended to reduce diversity in the timing and content of disclosures that companies commonly provide in their footnotes. Under the new standard, management must decide whether there are conditions or events, considered in the aggregate, that raise substantial doubt about the company’s ability to continue as a going concern within one year after the date that the financial statements are issued, or within one year after the date that the financial statements are available to be issued when applicable. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

In April 2015, the FASB issued Accounting Standards Update 2015-03, Interest-Imputation of Interest (Subtopic 835-30): Simplifying the Presentation of Debt Issuance Costs. To simplify presentation of debt issuance costs, this new standard requires that debt issuance costs related to a recognized debt liability be presented in the balance sheet as a direct deduction from the carrying amount of that debt liability, consistent with debt discounts.  The recognition and measurement guidance for debt issuance costs are not affected by this update.  This guidance is effective for annual reporting beginning after December 15, 2015, including interim periods within the year of adoption, and calls for retrospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2016. The Company’s consolidated balance sheet as of September 30, 2015 includes in assets $5.3 million of debt issuance costs classified as deferred financing costs.

 

In July 2015, the FASB issued Accounting Standards Update 2015-11, Simplifying the Measurement of Inventory (Topic 330). To simplify the principles for subsequent measurement of inventory, this new standard requires inventory measured using any method other than LIFO or the retail method shall be measured at the lower of cost and net realizable value, rather than lower of cost or market. This guidance is effective for annual reporting beginning after December 15, 2016, including interim periods within the year of adoption, and calls for prospective application, with early application permitted. Accordingly, the standard is effective for the Company on July 1, 2017. The adoption of this guidance is not expected to have a material impact on the Company’s consolidated financial statements.

 

XML 30 R23.htm IDEA: XBRL DOCUMENT v3.3.0.814
Liability Related to Sale of Future Royalties (Details)
$ in Thousands
1 Months Ended 3 Months Ended 4 Months Ended
Apr. 30, 2015
USD ($)
Sep. 30, 2015
USD ($)
Sep. 30, 2014
USD ($)
Jun. 30, 2015
USD ($)
Liability Related to Sale of Future Royalties        
Royalties on net sales of Kadcyla     $ 4,166  
Percentage of royalty payments if applicable threshold is met 85.00%      
Immunity Royalty Holdings, L.P        
Liability Related to Sale of Future Royalties        
Percentage of royalty payments 100.00%      
Royalties on net sales of Kadcyla $ 235,000      
Royalties on net sales of Kadcyla when royalties to the purchaser reach a specified milestone $ 260,000      
Percentage of royalty payments if applicable threshold is met 15.00%      
Proceeds from sale of future royalties $ 200,000      
Transaction costs incurred during royalty purchase agreement $ 5,900      
Movement in Deferred Revenue [Roll Forward]        
Liability related to sale of future royalties - beginning balance   $ 199,662    
Non cash Kadcyla royalty revenue   (5,684)    
Non cash interest expense recognized   4,851    
Liability related to sale of future royalties - ending balance   $ 198,829   $ 199,662
Effective annual interest rate       9.8
XML 31 R19.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Details 5)
$ in Millions
3 Months Ended
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
Segment Information    
Number of operating segments 1  
Recent Accounting Pronouncements    
Deferred financing costs | $ $ 5.3  
Biotest | Revenues Percentage    
Collaborative Partner:    
Percentages of revenue recognized 16.00% 11.00%
Lilly | Revenues Percentage    
Collaborative Partner:    
Percentages of revenue recognized 35.00% 3.00%
Sanofi | Revenues Percentage    
Collaborative Partner:    
Percentages of revenue recognized 0.00% 45.00%
Roche | Revenues Percentage    
Collaborative Partner:    
Percentages of revenue recognized 38.00% 32.00%
XML 32 R15.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Details)
1 Months Ended 3 Months Ended
Oct. 31, 2015
USD ($)
Dec. 31, 2013
USD ($)
May. 31, 2013
USD ($)
item
Dec. 31, 2012
USD ($)
item
Dec. 31, 2011
item
Nov. 30, 2011
item
Nov. 30, 2009
USD ($)
item
Sep. 30, 2009
USD ($)
item
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
item
Jun. 30, 2015
USD ($)
Jun. 30, 2014
USD ($)
Summary of Significant Accounting Policies                        
Number of types of licensing and development agreements with collaborative partners                 2      
License and milestone fees | $                 $ 6,070,000 $ 6,234,000    
Financial Instruments and Concentration of Credit Risk                        
Number of financial institutions in the U.S. in which cash and cash equivalents are primarily maintained                 3      
Number of marketable securities held by entity | $                 $ 0   $ 0  
Cash and cash equivalents | $                 $ 247,843,000 121,798,000 $ 278,109,000 $ 142,261,000
Development and Commercialization License                        
Summary of Significant Accounting Policies                        
Average involvement period over which the upfront payments on single-target licenses are amortized                 6 years 6 months      
Difference between the full cost to manufacture and amounts received from collaborators for preclinical and clinical materials | $                 $ 7,000,000 3,100,000    
Number of types of milestone payments under collaborative arrangements                 3      
Number of quarters in arrear for revenue recognition                 1      
Development and Commercialization License | Minimum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 10 years      
Development and Commercialization License | Maximum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 12 years      
Development and Commercialization License | Kadcyla | Minimum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 10 years      
Development and Commercialization License | Kadcyla | Maximum                        
Summary of Significant Accounting Policies                        
Period to earn royalty payments                 12 years      
Right-to-test agreement | Minimum                        
Summary of Significant Accounting Policies                        
Average period over which upfront payments are deferred and recognized                 12 months      
Right-to-test agreement | Maximum                        
Summary of Significant Accounting Policies                        
Average period over which upfront payments are deferred and recognized                 18 months      
Amgen | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses           3     4      
License exercise fee | $       $ 1,000,000     $ 1,000,000 $ 1,000,000        
Amgen | Development and Commercialization License | Non-exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses     1                  
License exercise fee | $     $ 500,000                  
Amgen | Right-to-test agreement | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses       3     3 3        
Bayer HealthCare | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Biotest | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Lilly | Development and Commercialization License | Phase I clinical trial                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 2      
Lilly | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 3      
Lilly | Right-to-test agreement                        
Summary of Significant Accounting Policies                        
Number of single-target licenses         3              
Novartis | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 5      
Number of licenses to two related targets                 1      
Number of related targets                 2      
Roche | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 5      
Sanofi | Development and Commercialization License                        
Summary of Significant Accounting Policies                        
Number of related targets                 1      
License exercise fee | $   $ 2,000,000                    
License and milestone fees | $                   $ 1,700,000    
Sanofi | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                 1      
Number of licenses to multiple individual targets                 1      
Oxford BioTherapeutics Ltd Member | Amgen | Development and Commercialization License | Exclusive license                        
Summary of Significant Accounting Policies                        
Number of single-target licenses                   1    
Subsequent event | Sanofi | Development and Commercialization License | Phase I clinical trial                        
Summary of Significant Accounting Policies                        
License and milestone fees | $ $ 2,000,000                      
XML 33 R13.htm IDEA: XBRL DOCUMENT v3.3.0.814
Liability Related to Sale of Future Royalties (Tables)
3 Months Ended
Sep. 30, 2015
Liabilities Related to Sale of Future Royalties  
Schedule of Liability account during the period from the inception of the royalty transaction

 

The following table shows the activity within the liability account during the three-month period ended September 30, 2015 (in thousands):

 

 

 

Period from
June 30, 2015 to
September 30,
2015

 

Liability related to sale of future royalties — beginning balance

 

$

199,662

 

Non-cash Kadcyla royalty revenue

 

(5,684

)

Non-cash interest expense recognized

 

4,851

 

 

 

 

 

Liability related to sale of future royalties — ending balance

 

$

198,829

 

 

XML 34 R14.htm IDEA: XBRL DOCUMENT v3.3.0.814
Commitments and Contingencies (Tables)
3 Months Ended
Sep. 30, 2015
Commitments and Contingencies  
Minimum rental commitments for the next five fiscal years and thereafter under the non-cancelable operating lease agreements

 

The minimum rental commitments for the Company’s facilities, including real estate taxes and other expenses, for the next five fiscal years and thereafter under the non-cancelable operating lease agreements discussed above are as follows (in thousands):

 

2016 (nine months remaining)

 

$

5,519

 

2017

 

7,147

 

2018

 

7,253

 

2019

 

6,441

 

2020

 

6,423

 

Thereafter

 

38,857

 

Total minimum lease payments

 

$

71,640

 

Total minimum rental payments from sublease

 

(340

)

Total minimum lease payments, net

 

$

71,300

 

 

 

XML 35 R16.htm IDEA: XBRL DOCUMENT v3.3.0.814
Summary of Significant Accounting Policies (Details 2) - Recurring basis - USD ($)
$ in Thousands
Sep. 30, 2015
Jun. 30, 2015
Fair value hierarchy for the Company's financial assets measured at fair value    
Cash equivalents $ 240,643 $ 269,304
Quoted Prices in Active Markets for Identical Assets (Level 1)    
Fair value hierarchy for the Company's financial assets measured at fair value    
Cash equivalents $ 240,643 $ 269,304
XML 36 R21.htm IDEA: XBRL DOCUMENT v3.3.0.814
Collaborative Agreements (Details 2)
1 Months Ended 3 Months Ended
Oct. 31, 2013
USD ($)
May. 31, 2013
USD ($)
item
Dec. 31, 2012
USD ($)
item
Nov. 30, 2011
USD ($)
item
Nov. 30, 2009
USD ($)
item
Sep. 30, 2009
USD ($)
item
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
Collaborative Agreements disclosures                
Amount of arrangement consideration included in license and milestone fees             $ 6,070,000 $ 6,234,000
Costs related to the research and development services             35,132,000 $ 28,018,000
Amgen | Development milestones | Phase II clinical trial                
Collaborative Agreements disclosures                
Potential milestone payments             3,000,000  
Amgen | Development and Commercialization License                
Collaborative Agreements disclosures                
Potential milestone payments $ 34,000,000              
Amgen | Development and Commercialization License | IND application effective                
Collaborative Agreements disclosures                
Potential milestone payments   $ 1,000,000            
Amount of arrangement consideration included in license and milestone fees             $ 1,000,000  
Number of milestone payments received | item       2        
Fee received per license       $ 1,000,000        
Amgen | Development and Commercialization License | Development milestones                
Collaborative Agreements disclosures                
Potential milestone payments 9,000,000              
Amgen | Development and Commercialization License | Regulatory milestones                
Collaborative Agreements disclosures                
Potential milestone payments 20,000,000              
Amgen | Development and Commercialization License | Sales milestones                
Collaborative Agreements disclosures                
Potential milestone payments 5,000,000              
Amgen | Development and Commercialization License | Exclusive license                
Collaborative Agreements disclosures                
Number of single-target licenses | item       3     4  
Fee received per license     $ 1,000,000   $ 1,000,000 $ 1,000,000    
Fee received on conversion of non-exclusive license agreement to an exclusive license $ 500,000              
Amgen | Development and Commercialization License | Non-exclusive license                
Collaborative Agreements disclosures                
Number of single-target licenses | item   1            
Fee received per license   $ 500,000            
Amgen | Right-to-test agreement | Exclusive license                
Collaborative Agreements disclosures                
Number of single-target licenses | item     3   3 3    
XML 37 R5.htm IDEA: XBRL DOCUMENT v3.3.0.814
CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Thousands
3 Months Ended
Sep. 30, 2015
Sep. 30, 2014
Cash flows from operating activities:    
Net loss $ (33,740) $ (22,282)
Adjustments to reconcile net loss to net cash used for operating activities:    
Non-cash royalty revenue related to sale of future royalties (5,684)  
Non-cash interest expense on liability related to sale of future royalties 5,143  
Depreciation and amortization 1,127 1,389
Gain on sale/disposal of fixed assets (6)  
Stock and deferred share unit compensation 5,783 5,410
Deferred rent 29 92
Change in operating assets and liabilities:    
Accounts receivable (1,724) 58
Unbilled revenue (185) 545
Inventory 1,689 835
Prepaid and other current assets 95 525
Other assets 62 105
Accounts payable 1,551 138
Accrued compensation (5,084) (3,153)
Other accrued liabilities (871) 29
Deferred revenue 464 (2,983)
Proceeds from landlord for tenant improvements   393
Net cash used for operating activities (31,351) (18,899)
Cash flows from investing activities:    
Purchases of property and equipment (3,377) (1,708)
Net cash used for investing activities (3,377) (1,708)
Cash flows from financing activities:    
Proceeds from stock options exercised 4,462 144
Net cash provided by financing activities 4,462 144
Net change in cash and cash equivalents (30,266) (20,463)
Cash and cash equivalents, beginning balance 278,109 142,261
Cash and cash equivalents, ending balance $ 247,843 $ 121,798
XML 38 R10.htm IDEA: XBRL DOCUMENT v3.3.0.814
Commitments and Contingencies
3 Months Ended
Sep. 30, 2015
Commitments and Contingencies  
Commitments and Contingencies

E.     Commitments and Contingencies

 

Leases

 

Effective July 27, 2007, the Company entered into a lease agreement with Intercontinental Fund III for the rental of approximately 89,000 square feet of laboratory and office space at 830 Winter Street, Waltham, MA through March 2020. The Company uses this space for its corporate headquarters and other operations. In December 2013, the Company modified its lease agreement at 830 Winter Street, Waltham, MA to include approximately 19,000 square feet of additional office space through 2020, concurrent with the remainder of the original lease term. As part of the lease amendment, the Company received a construction allowance of approximately $746,000 to build out office space to the Company’s specifications. The Company obtained physical control of the additional space to begin construction in January 2014. In April, 2014, the Company again modified its lease agreement at this site to extend the lease to 2026. The Company may extend the lease for two additional terms of five years. As part of this lease amendment, the Company received a construction allowance of approximately $1.1 million to build out office space to the Company’s specifications. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.

 

The Company also leases manufacturing and office space at 333 Providence Highway, Norwood, MA under an agreement through 2018 with an option to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount.

 

Effective April 2013, the Company entered into a lease agreement with River Ridge Limited Partnership for the rental of 7,507 square feet of additional office space at 100 River Ridge Drive, Norwood, MA. The initial term of the lease is for five years and two months commencing in July 2013 with an option for the Company to extend the lease for an additional term of five years. The Company is required to pay certain operating expenses for the leased premises subject to escalation charges for certain expense increases over a base amount. The Company entered into a sublease in December 2014 for this space, effective January 2015 through July 2018.

 

The minimum rental commitments for the Company’s facilities, including real estate taxes and other expenses, for the next five fiscal years and thereafter under the non-cancelable operating lease agreements discussed above are as follows (in thousands):

 

2016 (nine months remaining)

 

$

5,519

 

2017

 

7,147

 

2018

 

7,253

 

2019

 

6,441

 

2020

 

6,423

 

Thereafter

 

38,857

 

Total minimum lease payments

 

$

71,640

 

Total minimum rental payments from sublease

 

(340

)

Total minimum lease payments, net

 

$

71,300

 

 

There are no obligations under capital leases as of September 30, 2015, as all of the capital leases were single payment obligations which have all been made.

 

Collaborations

 

The Company is contractually obligated to make potential future success-based development, regulatory or sales milestone payments in conjunction with certain collaborative agreements. These payments are contingent upon the occurrence of certain future events and, given the nature of these events, it is unclear when, if ever, the Company may be required to pay such amounts. Further, the timing of any future payment is not reasonably estimable. As of September 30, 2015, the maximum amount that may be payable in the future under the Company’s current collaborative agreements is $162 million, $1.4 million of which is reimbursable by a third party under a separate agreement.

 

 

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Collaborative Agreements (Details)
$ in Thousands
1 Months Ended 3 Months Ended
Sep. 30, 2015
USD ($)
Dec. 31, 2011
USD ($)
item
Sep. 30, 2015
USD ($)
item
Sep. 30, 2014
USD ($)
Dec. 31, 2014
USD ($)
Dec. 31, 2013
USD ($)
Collaborative Agreements disclosures            
Amount of arrangement consideration included in license and milestone fees     $ 6,070 $ 6,234    
Costs related to the research and development services     $ 35,132 $ 28,018    
Lilly | Right-to-test agreement            
Collaborative Agreements disclosures            
Payments received under collaboration agreement   $ 20,000        
Number of development and commercialization licenses taken | item   3        
Lilly | Right-to-test agreement | No exercise fee            
Collaborative Agreements disclosures            
License exercise fee, per subsequent license   $ 0        
Lilly | Right-to-test agreement | Exercise fee of $2 million            
Collaborative Agreements disclosures            
License exercise fee, per subsequent license   $ 2,000       $ 2,000
Lilly | Development and Commercialization License | Exclusive license            
Collaborative Agreements disclosures            
Number of development and commercialization licenses taken | item     3      
Lilly | Development and Commercialization License | No exercise fee            
Collaborative Agreements disclosures            
Number of development and commercialization licenses taken | item     1      
Lilly | Development and Commercialization License | No exercise fee | Maximum            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         $ 200,500  
Lilly | Development and Commercialization License | Exercise fee of $2 million            
Collaborative Agreements disclosures            
Number of development and commercialization licenses taken | item   2 2      
License exercise fee, per subsequent license         2,000  
Lilly | Development and Commercialization License | Exercise fee of $2 million | Maximum            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         199,000  
Lilly | Development and Commercialization License | Phase I clinical trial            
Collaborative Agreements disclosures            
Number of development and commercialization licenses taken | item     2      
Lilly | Development and Commercialization License | Development milestones | No exercise fee            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         30,500  
Lilly | Development and Commercialization License | Development milestones | Exercise fee of $2 million            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         29,000  
Lilly | Development and Commercialization License | Development milestones | Phase I clinical trial            
Collaborative Agreements disclosures            
Payments received under collaboration agreement $ 5,000          
Potential milestone payments for each subsequent license 5,000   $ 5,000      
Lilly | Development and Commercialization License | Development milestones | Phase II clinical trial            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license $ 9,000   $ 9,000      
Lilly | Development and Commercialization License | Regulatory milestones            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         70,000  
Lilly | Development and Commercialization License | Sales milestones            
Collaborative Agreements disclosures            
Potential milestone payments for each subsequent license         $ 100,000