-----BEGIN PRIVACY-ENHANCED MESSAGE----- Proc-Type: 2001,MIC-CLEAR Originator-Name: webmaster@www.sec.gov Originator-Key-Asymmetric: MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB MIC-Info: RSA-MD5,RSA, Cq6uqPYNPDTz6I9d3E3I5lxOYU6l+KUnu9fKGvIZqBW3s7+qk3OV2XzEI12wzqTy 23ZZGbGx1xrL+HRozp3lSg== 0000950130-97-001600.txt : 19970409 0000950130-97-001600.hdr.sgml : 19970409 ACCESSION NUMBER: 0000950130-97-001600 CONFORMED SUBMISSION TYPE: 8-K PUBLIC DOCUMENT COUNT: 1 CONFORMED PERIOD OF REPORT: 19970402 ITEM INFORMATION: Other events FILED AS OF DATE: 19970408 SROS: NASD FILER: COMPANY DATA: COMPANY CONFORMED NAME: ROBERTS PHARMACEUTICAL CORP CENTRAL INDEX KEY: 0000853022 STANDARD INDUSTRIAL CLASSIFICATION: PHARMACEUTICAL PREPARATIONS [2834] IRS NUMBER: 222429994 STATE OF INCORPORATION: NJ FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 8-K SEC ACT: 1934 Act SEC FILE NUMBER: 000-19173 FILM NUMBER: 97576167 BUSINESS ADDRESS: STREET 1: MERIDIAN CENTRE II STREET 2: 4 INDUSTRIAL WAY W CITY: EATONTOWN STATE: NJ ZIP: 07724 BUSINESS PHONE: 9083891182 MAIL ADDRESS: STREET 1: MERIDIAN CTR II STREET 2: 4 INDUSTRIAL WAY WEST CITY: EATONTOWN STATE: NJ ZIP: 07724 8-K 1 FORM 8-K FORM 8-K SECURITIES AND EXCHANGE COMMISSION WASHINGTON, D.C. 20549 CURRENT REPORT Pursuant to Section 13 or 15(d) of the Securities Exchange Act of 1934 Date of Report (Date of earliest event reported): April 2, 1997 ROBERTS PHARMACEUTICAL CORPORATION - -------------------------------------------------------------------------------- (exact name of registrant as specified in its charter) NEW JERSEY 1-1-432 22-2429994 - ------------------- ------------- ----------------- (State or other (Commission (IRS Employer jurisdiction of File Number) Identification incorporation) Number) Meridian Center II 4 Industrial Way West Eatontown, New Jersey 07724 - -------------------------------------------------------------------------------- (Address of principal executive offices, including zip code) Registrant's telephone number, including area code: 908-389-1182 Meridian Center II 4 Industrial Way West Eatontown, New Jersey 07724 - -------------------------------------------------------------------------------- (Former name or former address, if changed from last report) - 2 - Item 5. Other Events ------------ Roberts Pharmaceutical Corporation, through its wholly owned subsidiary Roberts Laboratories Inc., has received an exclusive license from Pfizer Inc. to develop and market Sampatrilat, a novel new compound to treat essential hypertension and congestive heart failure. The agreement provides for transfer of data and assignment of patent rights to Roberts from Pfizer. Sampatrilat incorporates, in a single substance, two different but complimentary modes of activity. It is a potent inhibitor of angiotensin converting enzyme (ACE) and therefore offers benefits of ACE inhibitors such as captopril. Sampatrilat also inhibits neutral endopeptidase which, in turn results in an elevation of atrial natriuretic factor (ANF), the body's own natural diuretic. This dual mode of activity may offer patients and managed care providers the potential advantages of a treatment regime involving fewer drugs, reduced risks, and lower costs in comparison to existing therapies. Today, treatment of uncomplicated essential hypertension follows a step therapy paradigm with the initial treatment usually being an ACE inhibitor. However, normalization of blood pressure may require the addition of a second drug, generally a diuretic, in combination with the ACE inhibitor. This type of step therapy, involving two and sometimes three drugs, can have consequences in the form of side effects that include the separate and additive adverse reactions of the different products. Diuretics commonly employed with ACE inhibitors can produce side effects that include potassium depletion, gout, elevated blood lipids, and abnormalities in sugar metabolism. Because ANF is a natural diuretic that does not possess these properties, the use of Sampatrilat in hypertension or heart failure patients may confer, through the administration of a single drug, all the advantages of a pure ACE inhibitor with the addition of greater natriuresis (sparing the use of diuretics). The Company noted that this is their second strategic alliance, in the past few months, with a major pharmaceutical company for development of compounds representing significant new therapeutic potentials for very large markets. - 2 - ROBERTS PHARMACEUTICAL CORPORATION ---------------------------------- (Registrant) Date: April 8, 1997 By: /s/ Anthony A. Rascio --------------------- Anthony A. Rascio Vice President -----END PRIVACY-ENHANCED MESSAGE-----