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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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<SEC-DOCUMENT>0000000000-06-001726.txt : 20060831
<SEC-HEADER>0000000000-06-001726.hdr.sgml : 20060831
<ACCEPTANCE-DATETIME>20060111162255
<PRIVATE-TO-PUBLIC>
ACCESSION NUMBER:		0000000000-06-001726
CONFORMED SUBMISSION TYPE:	UPLOAD
PUBLIC DOCUMENT COUNT:		1
FILED AS OF DATE:		20060111

FILED FOR:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			CYTYC CORP
		CENTRAL INDEX KEY:			0000849778
		STANDARD INDUSTRIAL CLASSIFICATION:	LABORATORY ANALYTICAL INSTRUMENTS [3826]
		IRS NUMBER:				020407755
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		UPLOAD

	BUSINESS ADDRESS:	
		STREET 1:		250 CAMPUS DRIVE
		CITY:			MALBOROUGH
		STATE:			MA
		ZIP:			01752
		BUSINESS PHONE:		5082638495

	MAIL ADDRESS:	
		STREET 1:		250 CAMPUS DRIVE
		CITY:			MALBOROUGH
		STATE:			MA
		ZIP:			01752
PUBLIC REFERENCE ACCESSION NUMBER:		0001047469-05-004050
</SEC-HEADER>
<DOCUMENT>
<TYPE>LETTER
<SEQUENCE>1
<FILENAME>filename1.txt
<TEXT>


Mail Stop 6010

      	January 11, 2006

Mr. Timothy M. Adams
Vice President, Chief Financial Officer and Treasuer
Cytyc Corporation
250 Campus Drive
Marlborough, MA 01752

      Re:	Cytyc Corporation
      Form 10-K for the fiscal year ended December 31, 2004
      Filed February 26, 2005
      File No. 000-27558

Dear Mr. Adams:

	We have completed our review of your Form 10-K and related
filings and do not, at this time, have any further comments.


							Sincerely,


							Martin F. James
							Senior Assistant Chief
Accountant


</TEXT>
</DOCUMENT>
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