Note 3 - Income Taxes - Income Tax Rate Reconciliation (Details)	12 Months Ended
	Dec. 31, 2021	Dec. 31, 2020
Provision at the U.S. federal statutory rate	21.00%	21.00%
State taxes, net of federal benefit	(15.50%)	1.50%
Foreign tax rate differential	(30.20%)	0.50%
Valuation allowance	(1504.60%)	(13.90%)
Chile outside basis differential	34.40%	0.00%
PPP Loan Forgiveness	(484.60%)	0.00%
Accrual to return	(329.30%)	0.00%
Research and development credit	(144.90%)	0.00%
State rate change	(124.00%)	(6.50%)
China deferred adjustment	1006.00%	0.00%
China enterprise tax	0.00%	(2.10%)
Share based compensation	1590.30%	(2.00%)
Other true up	0.00%	(2.70%)
Intangible assets impairment and other non-deductibles	0.00%	1.80%
Other	2.00%	1.00%
Income tax (expense) benefit effective rate	20.60%	(1.40%)