February 17, 1994


                      DREYFUS LIFE AND ANNUITY INDEX FUND, INC.

                              Supplement to Prospectus
                                Dated April 30, 1993


      The following information supplements and should be read in
conjunction with the section of the Fund's Prospectus entitled "Management
of the Fund."

      The Dreyfus Corporation ("Dreyfus") has entered into an Agreement and
Plan of Merger providing for the merger of Dreyfus with a subsidiary of
Mellon Bank Corporation ("Mellon").

      Following the merger, it is planned that Dreyfus will be a direct
subsidiary of Mellon Bank, N.A.  Closing of this merger is subject to a
number of contingencies, including receipt of certain regulatory approvals
and approvals of the stockholders of Dreyfus and of Mellon.  The merger is
expected to occur in mid-1994, but could occur significantly later.


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      The following information supplements and should be read in
conjunction with the section of the Fund's Prospectus entitled "Condensed
Financial Information."

      Further information about the Fund's performance will be contained in
the Fund's annual report for the fiscal year ended December 31, 1993, which
will be available at approximately the end of February 1994 and may be
obtained without charge by writing to the address or calling the number
contained on the cover page of this Prospectus.