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Stockholders' Equity (Details Narrative) - USD ($)
1 Months Ended 12 Months Ended
Dec. 14, 2017
Sep. 27, 2017
Sep. 25, 2017
Apr. 14, 2017
Feb. 28, 2017
Feb. 16, 2017
Jan. 19, 2017
Dec. 05, 2016
Dec. 05, 2016
Oct. 19, 2016
Aug. 01, 2016
Jun. 30, 2016
Apr. 04, 2016
Mar. 07, 2016
Feb. 03, 2016
Jan. 08, 2016
Dec. 31, 2017
Feb. 28, 2017
Jan. 31, 2017
Dec. 31, 2017
Dec. 31, 2016
Jun. 03, 2016
Proceeds from direct offering             $ 8,900,000                   $ 2,000,000 $ 4,500,000 $ 8,900,000      
Number of common stock issued             1,399,140                              
Sale of stock price per share             $ 2.01                              
Number of warrants issued for common stock             3,426,731                              
Prefunded warrants price per share             $ 2.00                              
Warrant purchase price per share             $ 0.01                              
Proceeds from common stock                                       $ 16,535,000 $ 14,472,000  
Number of common stock issued value                                       $ 15,321,000 $ 13,949,000  
Reverse stock split description                           Immediately following the close of trading on March 7, 2016, the Company effected a one-for-twelve reverse stock split of its common stock. With the reverse stock split, every twelve shares of the Company’s issued and outstanding common stock were combined into one issued and outstanding share of common stock.                
Reverse stock split number of authorized shares                                 100,000,000     100,000,000 100,000,000  
Common stock issued for extinguishment of debt, value                                       $ 325,000 $ 850,000  
Loss on extinguishment of the debt                                       $ (39,000) $ (3,322,000)  
Mesa SPA [Member]                                            
Sale of common stock, units                   100,000                        
Fair value of shares issued                   $ 100,000                        
RCF Loan [Member]                                            
Common stock issued for extinguishment of debt               2,487,562                         38,086  
Common stock issued for extinguishment of debt, value               $ 2,500,000                         $ 200,000  
Induced conversion of debt               5,800,000                            
Extinguishment of debt amount               2,500,000                            
Loss on extinguishment of the debt               $ 3,300,000                            
Esousa [Member]                                            
Common stock issued for extinguishment of debt                 44,914                          
Common stock issued for extinguishment of debt, value                 $ 2,500,000                          
Fair value of shares issued                 $ 61,981                          
Anatolia [Member]                                            
Share issued price per share                     $ 1.42 $ 1.60       $ 6.00            
Number of shares issued for fees related during the period                     50,665 47,229       117,097            
Number of shares issued for fees related during the period value                     $ 100,000 $ 100,000       $ 700,000            
Registered Direct Offerings [Member]                                            
Proceeds from direct offering                         $ 1,200,000   $ 800,000              
Sale of stock price per share                         $ 2.17                  
Number of warrants issued for common stock                         200,000                 200,000
Prefunded warrants price per share                         $ 2.16                  
Warrant purchase price per share                         $ 0.01                  
Sale of common stock, units                         375,000   296,666              
Proceeds from issuance of warrants                         $ 400,000                  
Warrant exercisable term                         3 years                  
Maximum [Member]                                            
Reverse stock split reduced number of shares                           61,800,000                
Reverse stock split number of authorized shares                           200,000,000                
Minimum [Member]                                            
Reverse stock split reduced number of shares                           5,200,000                
Reverse stock split number of authorized shares                           100,000,000                
Investor [Member]                                            
Number of common stock issued         150,000                                  
Number of common stock issued value         $ 300,000                                  
Share issued price per share         $ 2.00                         $ 2.00        
Option Agreement [Member] | Aspire Capital [Member]                                            
Sale of common stock, units                             75,000              
Proceeds from sales of common stock                             $ 300,000              
Payments to acquire common stock                             $ 10,000,000              
ATM Offering [Member]                                            
Proceeds from direct offering       $ 30,000,000                                    
Number of common stock issued       812,723                                    
Commission percentage       2.50%                                    
Proceeds from common stock       $ 120,000                                    
Available for future sales       $ 2,880,000                                    
Aspire Capital Fund LLC [Member]                                            
Proceeds from direct offering     $ 22,000,000     $ 4,500,000                                
Number of common stock issued     880,000     2,100,000                                
Sale of stock price per share           $ 1.58                                
Number of warrants issued for common stock           748,101                                
Prefunded warrants price per share           $ 1.57                                
Warrant purchase price per share           $ 0.01                                
Warrants expiration term           3 years                                
Aspire Capital Fund LLC [Member] | Common Stock Purchase Agreement [Member]                                            
Proceeds from common stock $ 200,000 $ 2,000,000                                        
Number of common stock purchased 150,000 1,428,571                                        
Aspire Capital Fund LLC [Member] | Common Stock Purchase Agreement [Member] | Maximum [Member]                                            
Sale of common stock, units     5,033,677                                      
Aspire Capital Fund LLC [Member] | Common Stock Purchase Agreement [Member] | Minimum [Member]                                            
Share issued price per share     $ 1.38                                      
Aspire Capital Fund LLC [Member] | March 01, 2018 [Member] | Common Stock Purchase Agreement [Member]                                            
Available for future sales $ 19,800,000                                          
Remained available future sales $ 22,000,000