Stock-Based Compensation - Summary of Stock Options Outstanding (Details) - $ / shares	9 Months Ended
Sep. 30, 2018	Sep. 30, 2017
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]
Number of stock options outstanding, Beginning of period	286,174	110,828
Number of stock options outstanding, Granted	812,689	189,164
Number of stock options outstanding, Expired	(80,412)	(6,001)
Number of stock options outstanding, End of period	1,018,451	293,991
Number of stock options Exercisable, End of period	1,018,451	104,722
Weighted average exercise price, Beginning of period	$ 5.53	$ 18.24
Weighted average exercise price, Granted	0.98	1.40
Weighted average exercise price, Expired	5.24	104.67
Weighted average exercise price, End of period	1.91	5.64
Weighted average exercise price Exercisable, End of period	$ 1.91	$ 13.26

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The number of shares into which fully or partially vested stock options outstanding as of the balance sheet date can be currently converted under the option plan.

+ References

Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (c)(1)(iii)
-URI http://asc.fasb.org/extlink&oid=109197908&loc=d3e5070-113901

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The weighted-average price as of the balance sheet date at which grantees can acquire the shares reserved for issuance on vested portions of options outstanding and currently exercisable under the stock option plan.

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Number of options or other stock instruments for which the right to exercise has lapsed under the terms of the plan agreements.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
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Gross number of share options (or share units) granted during the period.

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Number of options outstanding, including both vested and non-vested options.

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Weighted average price at which grantees can acquire the shares reserved for issuance under the stock option plan.

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Reference 1: http://fasb.org/us-gaap/role/ref/legacyRef
-Publisher FASB
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Weighted average price at which grantees could have acquired the underlying shares with respect to stock options of the plan that expired.

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Weighted average per share amount at which grantees can acquire shares of common stock by exercise of options.

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