Stockholders' Equity and Share-Based Compensation (Details - Share Based Compensation) - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Share-based compensation expense	$ 295,123	$ 1,308,008
Research and Development Expense [Member]
Share-based compensation expense	123,652	498,913
General and Administrative Expense [Member]
Share-based compensation expense	$ 171,471	$ 809,095