Exhibit 23

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We hereby consent to incorporation by reference in the previously filed Registration Statement on Form S-8 File No. 333-65432 and Form S-3D File No. 333-96579 of Middlefield Banc Corp. of our report dated February 10, 2006, which report appears in the December 31, 2005, Annual Report on Form 10-K of Middlefield Banc Corp.

/s/ S.R. Snodgrass, A.C.

Wexford, PA
March 24, 2006