Note 3 - Somerset Acquisition, Goodwill, In-Process Research and Development and Other Intangible Assets - Summary of Goodwill and Intangible Assets (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2019	Dec. 31, 2018	Dec. 31, 2017
Balance, Goodwill	$ 13,074	$ 13,074
Reclassification of AZEDRA IPR&D
Goodwill, Impairment Loss	0	0
Amortization expense, Finite-lived Intangible Assets	(1,100)	(500)	$ (200)
Increase related to Somerset acquisition	4,773
Balance, Goodwill	17,847	13,074	13,074
Balance, Finite-lived Intangible Assets	6,223
In Process Research and Development [Member]
Balance, Finite-lived Intangible Assets	600	28,700
Reclassification of AZEDRA IPR&D		(4,900)
Impairment of 1404 IPR&D		(23,200)
Amortization expense, Finite-lived Intangible Assets
Increase related to Somerset acquisition
Balance, Finite-lived Intangible Assets	600	600	28,700
Other Intangible Assets [Member]
Balance, Finite-lived Intangible Assets	6,066	1,669
Reclassification of AZEDRA IPR&D		4,900
Impairment of 1404 IPR&D
Amortization expense, Finite-lived Intangible Assets	(1,088)	(503)
Increase related to Somerset acquisition	1,245
Balance, Finite-lived Intangible Assets	$ 6,223	$ 6,066	$ 1,669