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Note 8 - Commitments and Contingencies (Tables)
12 Months Ended
Dec. 31, 2019
Notes Tables  
Lease, Cost [Table Text Block]
Operating leases
 
December 31, 2019
 
Operating ROU lease assets, noncurrent
  $
13,493
 
Operating lease liabilities, current
   
599
 
Operating lease liabilities, noncurrent
   
15,005
 
Lessee, Operating Lease, Liability, Maturity [Table Text Block]
Years ending December 31,
 
Minimum Annual Payments
 
2020
  $
2,040
 
2021
   
2,076
 
2022
   
2,213
 
2023
   
2,255
 
2024
   
2,297
 
Thereafter
   
14,510
 
Total future minimum lease payments
 
 
25,391
 
Less imputed interest
   
(9,787
)
Total lease liabilities
 
$
15,604
 
Licensing Service and Supply Agreements [Table Text Block]
   
Paid from
inception/acquisition to
December 31, 2019
 
Future
Commitments
(1)
 
Terms
                 
Amgen Fremont, Inc. (formerly Abgenix)
  $
1,350
  $
5,750
 
Milestones and royalties to use XenoMouse
®
technology for generating fully human antibodies to PSMA LLC’s PSMA antigen.
                 
Former member of PSMA LLC
  $
504
  $
52,188
 
Annual minimum royalty payments and milestones to use technology related to PSMA.
                 
Selexis Commercial License Agreement
  $
124
  $
1,824
 
Milestones and royalties to use Selexis technology related to PSMA Antibodies.
                 
University of Zurich and the Paul Scherrer Institute
  $
590
  $
925
 
Annual maintenance and license fee payments, milestones and royalties in respect of licensed technology related to 1404.
                 
University of Western Ontario 2003 Agreement
  $
41
  $
151
 
Annual minimum royalty, administration and milestone payments in respect of licensed technology related to AZEDRA.
                 
Johns Hopkins University Technology
  $
435
  $
2,500
 
Annual minimum royalty payments and milestones to use technology related to PyL.